Ireviewed the recent papers on conscious sedation for gastrointestinal endoscopy, espe-dally the present state in Japan increasing in this decade. In 2000, the working group of JapanGastroenterological Endoscopy Society(JGES)reported that the incidence of adverse reactionof conscious sedation for gastrointestinal endoscopy was O.0006%(73/12, 043, 781)and 2 patientswere died caused by sedation between 1993 alld 1997. Compared with the report of the workinggroup in 1995, the incidence was decreased. One of the reasons why the incidence decreased wasconsidered that the guidelines and issues for conscious sedation from JGES enlightened theendoscopists. The drugs most often used in Japan were diazepam and midazolam(benzodiaze-pine), and the others were pethidine hydrochloricde (narcotic) and flunitrazepam(benzodiaze-pine). Recently, propofol, which has many merits besides quicker recovery time than mid-azolam, becomes popular in Western countries, and it will be popular in Japan in the nearfuture. To perform endoscopy in safety and painless, endoscopist should have correct knowl-edge for sedation and perform adequate monitoring during endoscopic procedures.
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