We assessed endoscopic mucosal resection (EMR) for superficial type early colorectal carcinoma (CRC), especially regarding its indication, choice of resection methods, and outcome. It was indicated that CRC even with submucosal massive invasion can be cured by complete EMR on conditions that the depth of sm invasion is within 1, 500, um and histologic grade at the deepest invasive portion is W or Mw, if there are no vessel involvement. However, cases with Mp or Por grade can never be curative by EMR, even if they showed a sm scanty invasion.
Limit of size in en block EMR using snare with one-channel colonoscope was considered 20 mm in average diameter. However, intentional piecemeal EMR for large colorectal intramucosal tumor, such as laterally spreading tumor (LST) is useful for curative EMR. Recently submucosal dissection EMR method using Hook knife, IT knife or Flex knife has enabled to perform endoscopic en block resection for large colorectal tumor as well as gastric carcinoma. However, it is needed to improve present procedure/device to easier one and standardize this technique to every general colonoscopist.
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