On 170 cases of chronic gastritis in total, gastric analysis was performed by the intubation method with caffeine in 80 cases and by the intubation method with histamine (0.5mg) in the other 90 cases. All the 170 cases were subjected to examination by tubeless method of gastric analysis using Kirex (Azure A-Resin Complex) and examination with gastrocamera. A comparative study of the results of the above examination led to the following conclusions:1. In the majority of achlorhydric cases who excreted less than 0.3 mg/300 cc of azure A in the two-hour urine, gastric analysis revealed less than 30 degrees of free hydrochloric acid after administration of caffeine or histamine and the total quantity of gastric juice was less than 100cc for two hours after histamine, even if the total quantity of gastric juice was less than 100cc for two hours after histamine. The gastric output of hydrochloric acid was less than 149 mg. within two hours after histamine, even if the total quantity of gastric juice was more than 100cc.2. In the majority of the cases with gastric acid who excreted more than 0.6mg/300cc of azure A in the two-hour urine, gastric analysis revealed more than 31 degrees of free hydrochloric acid, the total quantity of gastric juice was more than 100cc and the gastric output of hydrochloric acid was more than 150mg. within two hours after histamine.3. In about one-half of borderline cases in whom the excretion of azure A varied from 0.3 to 0.6 mg/300cc in the two-hour urine, gastric analysis revealed more than 31 degrees of free hydrochloric acid and the gastric output of hydrochloric acid was more than 150 mg. for two hours after histamine. In the other half of borderline cases, gastric analysis revealed less than 30 degrees of free hydrochloric acid, and the gastric output of hydrochloric acid was less than 149 mg for two hours after histamine.4. No significant relationship could be established between the results by the tubeless method with Kirex and the gastric acidity by the intubation method with caffeine.5. The tubeless gastric analysis with Kirex is not suitable for the quantitative measurement of hydrochloric acid secretion.6. A certain relationship was established among the results by the tubeless method with Kirex and by the intubation method with histamine and findings obtained with the gastrocamera.

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There is no radical therapy of stomach cancer except by surgical operations. It is most important to detct stomach cancer in the early stage. The author has studied on the diagnosis of stomach cancer using Gastrocamera in a man and an experimental applicatcion of ultraviolet photography on gastric mucosa in human resected stomachs, dogs, and mice in order to improve the diagnostic ability of gastrocamera.The results are as follows :A. Clinical Studies. One hundred and fifty-nine patients (male 112, female 47) were operated in the Tokyo University Hospital from Jun. 1955 to May. 1960, because of stomach cancer.1) Among them, 121 patients received either palliative or curative resection. 2) The Types of stomach cancer were divided into 4 groups by gastrocamera : ulcerating form (32.0% of the patients who received gastrocamera examinations), cancerous ulcer form (54.1%), tumor form (4.7%), and infiltrating form (10.2%). 3) The ratio of male to female was 5 : 2. The incidence of stomach cancer between 20 to 40 years of age was higher in women. 4) Patients who had ulcerating form tended to have complaints for long periods. 5) Three main symptoms of stomach cancer were epigastralgia, epigastric fullness and the loss of weight. 6) It was relatively easy to diagnose gastric cancer except ulcerating form with gastro camera. There exists many problems to differentiate ulcerating form from benign ulcers. The main diagnostic points were as follows : irregularity and bleeding of the floor of ulcer, vagueness and bleeding of the edge, broad spread of rednness into the surroundings, uneveness, irregularity and concurvature of the ridge, cessation of folds, and deformity of the arch.B. In earhy stomach cancer. 1) 17.3% among the resected cases were found to be stomach cancer in the early stage. 2) Predisposing position was the anterior wall of the body. 3) Most of the patients had complaints, such as epigastric pain, fullness, and distress, for a long time. 4) Characteristic f eaturers of early stomach cancer were i) relatively large and shallow ulcer with whity coats, ii) irregular margin which was invaded by cancer cells, iii) the cessation of folds. 5) Most of them were classified as the ulcerating form 6) Good results were obtained using gastrocamera.C. Experimental studies on the ultraviolet photography of stomach mucosa. 1) In mice ultraviolet photography revealed more precisely details of experimentally produced malignant ulcer by means of the inplantation of Ehrlich's cancer cell into the stomach mucosa than that of experimentally produced benign ulcer by means of the injection of Lantan-gel into stomach mucosa. 2) In the resected stomachs, ultraviolet photography revealed many characteristic featurers of malignant ulcer, 3) In the resected stomach of cancer in early stage, ultra-violet photography had many advantages. Above all, it revealed very clearly the form of ulcer, the extend of invasion of cancer cells, and the cessation of folds.

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