This report is concerned with contents of sodium and potassium in the various tissues removed from 48 dissected elderly patients with mean age of 78 years, and the relation between potassium concentrations in serum and in various tissues have been investigated.
Pieces of skeletal muscle, cardiac muscle, aorta, brain, spinal cord, kidney, lung, liver, pancreas, stomach, intestine, spleen, thyroid, adrenal, skin and adipose were ashed, and a flame photometer was used to determine the contents of sodium and potassium in the tissues.
The electrolytes contents of samples were expressed as amounts per kg wet weight.
Potassium and sodium contents were correlated negatively in skeletal muscles, but positively in intestines.
Potassium content of serum was correlated with those of skeletal muscle and intestine, but not correlated with kidney, liver and other various tissues.
In the emaciated group with hypoproteinemia and hypokalemia, the means for tissue potassium in skeletal muscle, heart muscle, lung, liver, intestine and spleen were lower significantly than those in the control elderly.
There were no statistical difference between these two groups for potassium contents in kidney, brain, thyroid, adrenal, skin and adipose.
As potassium has been considered an index of catabolism in tissue, these results may suggest the difference in the grade of catabolism in the various tissues.
In the disabled elderly, the enhanced catabolism and decreased potassium intake might cause tissue potassium depletion, which might be reflected in hypokalemia.
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