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Volume 10 (1970)
- Issue 4 Pages 135-
- Issue 3 Pages 133-
- Issue 2 Pages 63-
- Issue 1 Pages 1-
Volume 10, Issue 1
Displaying 1-7 of 7 articles from this issue
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EARLY LUNG CANCER AND BLEOMYCIN[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1970 Volume 10 Issue 1 Pages 1-7
Published: June 01, 1970
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSBleomycin was administered to 21 patients with lung cancer (primary lung cancer in 18 cases, metastatic lung cancer in 3 cases), and produced following results.Fibroblast-inhibiting agents were simultaneously administered as multiple combination therapy, “CPBP”, with chloroquine, phytona-Bleomycin and prednisolone.
Bleomycin therapy was performed in 21 cases of primary or metastatic lung cancer.In consequence, beneficial effect was seen in a fairly large number of cases including small sized lung cancer and terminal cancer cases. In comparison with other antineoplastic agents, Bleomycin had the advantage of not causing disturbances in host. It was slightly effective against pulmonary metastasis of osteosarcoma.
Side effects in 23 cases consisted in pneumonia-like symptoms in 2 cases, fever in 1 case, depilation in 1 case, neuralgia in 1 case, phlebitis in 1 case, anorexia in 1 case. No hematopoietic side effect appeared, nor was there any case in which distinct pulmonary fibrosis was observed.Pneumonialike symptoms disappeared on drug-withdrawal in our cases, and fibrosis was hardly seen.It was experimentally confirmed that changs in the lungs could be prevented by the use of fibroblast-inhibiting agent.
The fact that Bleomycin causes not much disturbances of host makes Bleomycin an extremely advantageous drug for chemotherapy of cancer. Its effect is especially remarkable, if used against early-stage lung cancer.View full abstractDownload PDF (9646K) -
Shitoo Yamada, Susumu Shimizu1970 Volume 10 Issue 1 Pages 9-14
Published: June 01, 1970
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSFor improving the cytological diagnosis of pulmonary cancer, there were investigated a method preparing a specimen of cancer cells alone by a multiple layer centrifugation method, a method deriving cancer cells by X ray irradiation and administration of anticancer agents and expectorants, and a pulmonary puncture with a needle of lmm.thick.
As to cases of the hilar type and the filtration type, a positive result is frequently obtained with a simple smear of sputum;however, as to cases of the atelectasis type, the tumor type, the pleura type, and the miliary type, the examination with a simple smear of sputum shows negative, and consequently, there is needed to employ the cancer-cell collecting method or the cancer-cell deriving method.In metastatic pulmonary tumor, the specimen should be collected by the pulmonary puncture, since cancer cells are not recognized in the sputum.View full abstractDownload PDF (1990K) -
Yoshio Okada, Sadao Ikeda, Motohiko Ito, Shintaro Sato, Hisanori Yukim ...1970 Volume 10 Issue 1 Pages 15-20
Published: June 01, 1970
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSThe prognosis from surgical treatment of small cell carcinoma is the poorest of all cell types of lung cancer. Nine of the40patients of small cell carcinoma underwent pulmonary resection is an attempt at cure. Of9patients undergoing resection, one lived for a period of 10 years, and one is alive and apparently well3years later.
As might be expected, the survivors had1) smaller tumor than3cm in diameter, 2) no involvement of the hilar lymph nodes, 3) distaler origination thean in segment bronchi, and 4) less degrees of invasion.View full abstractDownload PDF (6455K) -
Kinya Sawada, [in Japanese], [in Japanese], [in Japanese], [in Japanes ...1970 Volume 10 Issue 1 Pages 21-26
Published: June 01, 1970
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSBronchoscopy and cytology are important measures in diagnosis of lung cancer as well as radio graphy. At Aichi Cancer Hospital, all cases suspicious for lung cancer on x-ray study are examined with bronchoscopy under general anesthesia and also scratch cytology utilizing a small brush. One hundred ninety four cases of lung cancer were studied with bronchoscopy under general enesthesia.It was found that a controlled ventilation was most suitable for the anesthesia
A correct diagnosis was obtained in 72.9%of the case by the scrach cytology. If those cases were divoided by the “Bronchoscopic type”, “Radiographic type” or “Localization of origination”, the best diagnostic resslts wera obtained at solid tumor type, hilar type and at tumor originated from the stem of bronchus.
A satisfactory result was not obtained in cases located at periphery of the lung on radiogram.
A positive diagnosis, however, was obtained in 97.1%of the cases of tumor in the stem of bronchus, 80.0% in the periphery of bronchus and 88.6%in total cases by cytogy associated with exforiative and transthoracic cytology as scratch methode.
False negative cases should be carefully to elucidate the cases of error. A combined use of flexible fiberbronchoscopy, transthoracic cytology, thoraco scopy and mediastinoscopy should be con sidered to obtained better diagnostic result.View full abstractDownload PDF (990K) -
[in Japanese]1970 Volume 10 Issue 1 Pages 27-35
Published: June 01, 1970
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSThis paper reports the concenrations of urinary estrogen fractions excreted by 29 male patients with lung cancer including 12 cases of adenocarcinoma, 9 of squamous cell carcinoma 8 of anaplastic carcinoma.
Patients with lung cancer of the squamous type, excrete significantly more estrogen than healthy subjects. There were, however, no significant differences from the patients with adenocarcinoma, anaplastic carcinoma and healthy subjects.
Estrogen/17ks ratio is significantly higher in patients with lung cancer of the squamous type than patients with adenocarcinoma, the laters are presumed to excrete relatively less estrogen in urine.
Estradiol/estrone+estriol ratio is, however, higher in patients with adenocarcinoma than other histologic types of the lung cancer and healthy subject.
In patients with lung cancer and gynecomastia, the estrogen excretion is not always high, but the estradiol/estrone+estriol ratio is elevated in most of the cases.
The shift of estrogen fractions in the male patients with adenocarcinoma of the lung is related with the clinical fact that the incidence of gynecomastia is relatively high in the patient with adenocarcinoma of the lung. But, from this finding, the cause of the fact that the incidence of adenocarcinoma of the lung is higher in female than male is unknown.View full abstractDownload PDF (1372K) -
[in Japanese]1970 Volume 10 Issue 1 Pages 37-43
Published: June 01, 1970
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSDownload PDF (546K) -
[in Japanese]1970 Volume 10 Issue 1 Pages 44-51
Published: June 01, 1970
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSDownload PDF (1524K)
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