Haigan
Online ISSN : 1348-9992
Print ISSN : 0386-9628
ISSN-L : 0386-9628
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Volume 15, Issue 3
Displaying 1-4 of 4 articles from this issue
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  • The Application of Tumor Scintigraphy with 197HgCl2 to the Diagnosis of Lung Cancer
    Tadashige FUJII, Hisakata KANAI, Kenfiro HANDA, Shozo KUSAMA
    1975 Volume 15 Issue 3 Pages 159-169
    Published: September 15, 1975
    Released on J-STAGE: October 22, 2010
    DOIhttps://doi.org/10.2482/haigan.15.159
    JOURNAL FREE ACCESS
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    Lung Scintigraphy with 197HgCl2 was studied in 241 patients. Positive results were obtained in 76 cases (90.4%) out of 84 primary lung cancers. But in the benign conditions such as pulmonary tuberculosis, lung abscess and so on, positive results obtained also. This method seemed to be applicable as the screening and supplementary method for diagnosis of the intrathoracic lesions. The dual radionuclide subtraction techniques with 197HgCl2 and 131I-RISA were performed for diagnosis of lung cancer, using whole body scanner or scinticamera with a digital processor. Because parts of non-specific accumulation of 197HgCl2 was erased, so that hyperfixation of 197HgCl2 in the metastatic foci of the mediastinum and hilar region was more clarified. The degree of accumulation of 197HgCl2 was expressed as the radioactivity of 197HgCl2 to that of 131I-RISA ratio. The distribution ratio of this value in the lesion to the various organs was discussed.
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  • Improvement of Transbronchial Biopsy for Peripheral Lung Cancer
    Motor Drilling Method
    Junichi Yukutake
    1975 Volume 15 Issue 3 Pages 171-180
    Published: September 15, 1975
    Released on J-STAGE: October 22, 2010
    DOIhttps://doi.org/10.2482/haigan.15.171
    JOURNAL FREE ACCESS
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    The cytology is one of the most valuable diagnostic methods for pulmonary carcinomas. The author and his colleagues have been using the transbronchial biopsy for the peripherally located pulmonary carcinomas. However, it is of the utmost exhaustive efforts to establish the diagnosis for the peripherally located small tumors by the transbrachial biopsy. The author and his colleagues exaniined the relationships between the bronchi and the tumors in the above negative cases and obtained the following results, the bronchus was compressed by the tumor and its lumen, was narrowed, the bronchus was curved and obstructed, the wall of the tumor was thick or the bronchus was narrowed by the enlarged lympho nodes.
    A motor drilling method was developed for solving the problem.
    Among 118 cases of primary lung cancer, a positive rate was 81.9% by bronchial catheter and 84.9% by bronchial fibrescope: the motor drilling method was applied to the 15 negative cases and the positive rate of 86% was obtained. The result proves usefulness of the motor drilling method, and its safety, the variety of its application and the reliability were discussed.
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  • A model for tumor growth curve of human malignant tumor.
    YUKIMITSU TASEI
    1975 Volume 15 Issue 3 Pages 181-187
    Published: September 15, 1975
    Released on J-STAGE: October 22, 2010
    DOIhttps://doi.org/10.2482/haigan.15.181
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    Many analyses of tumor growth have been studied mathematically by other in vestigators in experimental animals and human tumors, and several models of tumor growth curve have been demonstrated.
    Usually, exponential or logistic growth curve is used as a well-fitting growth model for human tumors, especially primary and metastatic lung cancers. And it is not so difficult to make human tumors to fit on these growth curves. However, it is not seemed that these growth curves are enough to explane any biological and clinical validity.
    Generally, solid tumors are said to contain both proliferating and non-proliferating fractions. Therefore, in this paper, a new growth curve model taking 2 parameters of r and p into consideration is shown. These new parameters of r and p are as follows; r is dependent on the frequency or ability of cell divisions and the least number of cell division to grow as a tumor, if these tumor cells could have more than the least number, p is division probability during time interval t.
    As a result, a new model of tumor growth curve corresponds to the Gamma distribution, and the values of tumor volume measurement on the roentgenograms existsuccesively on this growth curve.
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  • [title in Japanese]
    1975 Volume 15 Issue 3 Pages 189-275
    Published: September 15, 1975
    Released on J-STAGE: October 22, 2010
    DOIhttps://doi.org/10.2482/haigan.15.189
    JOURNAL FREE ACCESS
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