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Volume 17, Issue 2
Displaying 1-9 of 9 articles from this issue
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Fumitaka Tanaka, Itsuro Ishida, Yasuo Seki, Kinya Sawada, Seigo Fukuma ...1977 Volume 17 Issue 2 Pages 91-101
Published: June 25, 1977
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSThin-walled cavity which was roentogenologically seen in the metastatic lung tumors from renal carcinoma, carcinoma of the pancreas and carcinoma of the larynx was presented and the morphological examination was performed on the surgical specimen and the necropsy material. Clinical and pathological evaluation on the thin walled cavity elucidated the developing mechanism of the cavity formation caused by the metastatic lung tumors. The cavity is thought to be due to the specific growth pattern of the metastasized malignant cells along the wall of the pre-existing pulmonary emphysematous or emphysematous cystic structure. And the ischemic necrosis or inherent properties of the tumor in the lung seem to be little contributory to the formation of the thin-walled cavity in the metastatic lung tumors.View full abstractDownload PDF (14657K) -
Hiroyuki SHIMIZU, Kunio AOKI, Tetsuo KUROISHI1977 Volume 17 Issue 2 Pages 103-112
Published: June 25, 1977
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSThe causal association between exposure to exhaust gas from cars and incidence of lung cancer was examined. Traffic volume was taken as an indicator of degree of exposure to exhaust gas. Subjects investigated were 732, 896 inhabitants living in the areas within 100 meters from the street and intersection in Nagoya city, 1969-1974, where more than 1, 000 cars pass through for 12 hours from 7 a.m. to 7 p.m. a day. During these six years there were 1, 182 deaths from lung cancer in Nagoya city, among them 476 deaths occurred in the studied areas.
Mortality rate of lung cancer increased in parallel with traffic volume, but no significant difference between them was observed. There is no difference of mortality rate from lung cancer between the four areas within 25m., 25-50m., 50-75m. and 75-100m. from the edge of the street or intersection.
Average age at death for lung cancer patients in each area by traffic volume was about the same. The area with high traffic volume is located on the central par of the city where other socio-environmental factors may give the Influence on incidence of lung cancer.View full abstractDownload PDF (1070K) -
Report from the 6 thoracic surgical units in Osaka district from 1966 to 1975Akira Masaoka, [in Japanese], [in Japanese], [in Japanese], [in Japane ...1977 Volume 17 Issue 2 Pages 113-118
Published: June 25, 1977
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSThe yearly transition of the patients of lung cancer. was investigated. 1024 cases at the 6 thoracic surgical units from 1966 to 1975 were analysed.
The results were as follows:
1) The number of patients and resected cases increased.
2) The number of over 70 year old patients increased, compared with the other age groups.
3) The parcentage of the squamous cell carcinoma and the small cell carcinoma increased.
4) The parcentage of the exploratory thoracotomies and the pneumonectomies in operative procedures decreased. On the contrary, the lobectomies increased steadily.
5) The number of cases in tuberculosis sanatoriums obviously increased.View full abstractDownload PDF (583K) -
Changes in cellular immune responses of patients in cancer therapyMasafumi Fujii, Taisuke Onoshi, Motoharu Sugiyama, Yasuo Urabe, Kenta ...1977 Volume 17 Issue 2 Pages 119-126
Published: June 25, 1977
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSCellular immunity in lung cancer was studied by means of lymphocyte transformation by phytohemagglutinin (PHA), purified protein derivative (PPD) skin test, absolute counts of peripheral lymphocytes and leucocyte migration inhibition test, The lymphocyte transformation by PHA was reduced in lung cancer patients in comparison with healthy controls, and correlated with the disease stage, but not with the histology type. The lymphocyte transformation became further depressed by cancer chemotherapy.
PPD skin reaction or absolute counts of peripheral lymphocytes did not correlate with the disease stage. However, all the three tests correlated with the disease stage. Therefore, these tests appeared to be general indices of the immunologic status. Inhibition of leucocyte migration was demonstrated in 35% of the patients with lung cancer, but not in patients with other cancers or infectious lung diseases or in healthy controls. These findings suggest the presence of tumor-associated antigens in lung cancer.
Concerning the effect of the streptococcal agent, OK-432, enhancement of the function of lymphocytes was observed in the parameters such as lymphocyte trans formation by PHA, PPD skin test and leucocyte migration inhibition test.View full abstractDownload PDF (797K) -
Tsutomu Yarita, [in Japanese], [in Japanese], [in Japanese], [in Japan ...1977 Volume 17 Issue 2 Pages 127-138
Published: June 25, 1977
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSAngiological and histopathological analysis of bronchopulmonary anastomosis for primary lung cancers were made.
The results obtained were as follows.
As the causes of broncho-pulmonary anastomosis (BPA), following 4 patterns were classified.
a) Bronchial arterial recanalization associated with tumor infiltration to pulmonary vessels
b) Anastomosis via vasa vasorum of pulmonary arteries in which tumor thrombosis was formed
c) Bronchial arterial recanalization via vasa vasorum due to occulsion of pulmonary artery by tumor invasion
d) Bronchial arterial recanalization by other pathogenesis prior to cancer development
The prognosis of all the patients showed BPA, especially in oat cell carcinoma, was extremely poor because of subsequent wide spread metastasis.View full abstractDownload PDF (12313K) -
Akio Koga, Takashi Nakamura, Takehiko Okuno, Satoru Matsuura, Terumasa ...1977 Volume 17 Issue 2 Pages 139-145
Published: June 25, 1977
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSA 50-year-old woman with adenoid cystic carcinoma in the origin of the left main bronchus was presented. The patient had been done total gastrectomy for stomach reticulosarcoma threee years previously.
Linac 6120 rads irradiation with Bleomycin 105mg administration was performed during one and a half months instead of excision because the surgical procedure of carcinal resection was seemed too heavy for the patient. After 3000 rads irradiation she had no dyspnea, and 4500 rads no hemosputum. But even after the total dosis of 6120 rads irradiation there was about one third amount of the tumor still remained in the anterior wall of the origin of the left main bronchus. Chemotherapies using Mitomycin C 40mg per os, MFC combination (Mitomycin C 40mg, 5-Fluorouracil 2500mg and Cytosine arabinoside 200mg I.V.), and 5-Fluorouracil 1500mg I. V. were done respectively during. the following one and a half years.
One year and four months after these therapies bronchofiberscopy revealed the tumor disappeared and there was just a slightly elevated area in the anterior wall of the origin of the left main bronchus. Punch biopsy showed basal cell hyperplasia histologically. The patient is now being well and having no sign of recurrence of the tumor two years after therapy. Both radiation and chemotherapy may have been effective for this patient with adenoid cystic carcinoma.View full abstractDownload PDF (5154K) -
Satoshi OKADA, Tomotoshi AKEMATSU, Zenju TAKEDA, Kentaro HASHIMOTO1977 Volume 17 Issue 2 Pages 147-152
Published: June 25, 1977
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSA 72-year-old female was admitted for the evaluation of cough and sputum. Bronchographic and broncoscopic examinations revealed a polypoid tumor in the right bronchus. The tumor was successfully removed. Microscopically, the tumor was composed of well-differentiated adipose tissue growing in the bronchial submucosa diagnosed as bronchial lipoma. The histogenesis of bronchial lipoma was discussed.View full abstractDownload PDF (5001K) -
1977 Volume 17 Issue 2 Pages 154-155
Published: June 25, 1977
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSDownload PDF (153K) -
1977 Volume 17 Issue 2 Pages 157-168
Published: June 25, 1977
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSDownload PDF (1652K)
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