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Volume 23 (1983)
- Issue 5 Pages 563-
- Issue 4 Pages 449-
- Issue 3 Pages 231-
- Issue 2 Pages 115-
- Issue 1 Pages 1-
Volume 23, Issue 5
Displaying 1-14 of 14 articles from this issue
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A Comparison of Ultrasonograms with Resected SpecimensKen Kodama, Takeo Sakurai, Hideki Yokoi, Shigetaka Tsuchihashi, Nobuyu ...1983 Volume 23 Issue 5 Pages 563-571
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSFifty-four patients with thoracic lesions underwent ultrasound examinations during the period April 1981-May 1982. Of 54 patients, 25 patients with tumorous lesions underwent operation, and all specimens were investigated in detail in comparison with the respective preoperative ultrasonographic patterns.
Pulmonary and mediastinal tumors just beneath the pleura or chest wall tumors were clearly described on echograms. Characteristics of the macroscopic findings of the inner structure of these tumors were well reflected on ultrasonograms. A majority of homogenous parenchymal pulmonary tumors showed a low level solid pattern. It was possible to confirm pleural indentation ultrasonographically.
Infiltration of peripheral lung cancer to the chest wall was demonstrated as an interruption of pleural high echo before clinical symptoms appeared.
The inner structures of mediastinal tumors were clearly described and distinguished by ultrasonograms preoperatively.
We conclude from these studies that ultrasonography is a useful new non-invasive diagnostic approach for demonstrating the inner structure of peripheral pulmonary tumors or mediastinal tumors and that it can clarify whether or not cancerous infiltration extends to the chest wall.View full abstractDownload PDF (17191K) -
Shimao Fukai, Tsuneo Ishihara, Shiro Yamazaki, Koichi Kobayashi, Iwao ...1983 Volume 23 Issue 5 Pages 573-581
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSFrom 1962 to April, 1980, a total of 491 patients with primary carcinoma of the lung were seen and treated in our department. One hundred and seventy-three (35.2%) of these patients had a histological diagnosis of adenocarcinoma. Resection was performed in 93 of these 173 patients.
The postoperative three-year survival rate was 50.0% in clinical stage I patients, 56.6% in the post-surgical histopathological stage I patients and 60.0% in patients who underwent curative resection of their primary tumor plus complete mediastinal lymph node dissection. On the contrary, the postoperative three-year survival rate was 7.1% in clinical stage III patients, 15.4% in the post-surgical histopathological stage III patients and none of 17 patients who underwent palliative resection survived three years. The postoperative three-year survival rate of females with adenocarcinoma of the lung was better than that of male.
Patients with radiological evidence of convergence in the pulmonary tissue adjoining the tumor and histological evidence of central fibrosis in the tumor tended to have a poor postoperative prognosis.View full abstractDownload PDF (944K) -
Iwao Takanami, Hideo Nakayama, Tsuneo Ishihara, Noboru Yanai1983 Volume 23 Issue 5 Pages 583-588
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSThe question of whether or not costus root oil (CRO) could be used clinically to evaluate immunological status in lung cancer patients was studied. After preliminary test I of sensitization and challenge conditions of CRO, 20% CRO mixed with linear alkylbenzene sulfonate (LAS) at 3% in petrolatum proved an adequate concentration and conditions for sensitization. Also 3% CRO in petrolatum proved an adequate concentration for challenge. In preliminany test II, 20% CRO + 3% LAS in petrolatum and 5%DNCB + 3% LAS in petrolatum were simultaneously patch tested in 155 chest diseasepatients. Two weeks later they were challenged with 3% CRO in petrolatum and 0.1% DNCB in ethanol. Reactions to CRO and DNCB were consistent in 145 of 155 patients (94%).
The sensitizing ability of CRO was judged almost equal to DNCB, when the above mentioned patch test conditions were adopted. After these preliminary tests, 81 lung cancer patients were tested for reaction to CRO. Reactions to the CRO skin test were positive in 68% of lung cancer patients.
The incidence of CRO reactions decreased with the advance of the disease lung cancer. CRO can be used as well as DNCB in diagnosing immunological -states in lung cancer. CRO may be useful to determing serial changes of the sensitizing ability in lung cancer patients who have already sensitized to DNCB.View full abstractDownload PDF (639K) -
Kazuo Kunishima, Kazuo Karasawa, Iwao Takagi, Motokazu Suyama1983 Volume 23 Issue 5 Pages 589-594
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSFifty-seven patients with lung cancer were surgically treated and their pre-and postoperative CEA levels of serum were measured at the Aichi Cancer Center Hospital from 1978 to 1980. The serum CEA was determined using a RIA kit (Dainabot). Positive cases were designated as those containing over 2.6 ng/ml CEA.
Twenty-five of a total of 57 cases (43.9%) were positive for CEA. On the basis of histologic types, 15 of 26 cases of adenocarcinoma (57.7%), 7 of 21 cases of squamous cell carcinoma (33.3%), 3 of 9 cases of large cell carcinoma (33.3%) were CEA-positive. The single case of small cell carcinoma was not positive. When the cases of lung cancer were classified according to pTNM stages, 16 of 37 cases in stage I (43.2%) showed a positive CEA value, as did 1 of 2 cases in stage II (50%), 5 of 14 cases in stage III (35.7%) and 3 of 4 cases in stage IV (75%). Regarding the size of the primary tumor of 47 resected cases, 1 of 6 cases with a tumor less than 2.0 cm in diameter (16.7%) was CEApositive, 5 of 15 cases with a tumor between 2.1 and 3.0 cm (33.3%), 8 of 18 cases with a tumor between 3.1 and 5.0 cm (44.4%) and 6 of 8 cases with a tumor over 5.1 cm (75%). Thirty-two cases whose CEA values declined after resection of tumor had no recurrent tumor and their postoperative courses were uneventful. On the other hand, in 8 cases postoperative CEA values were higher than preoperative ones. Of these 8 cases, 3 died 6, 8 and 14 months after the operation.
The percentage of CEA positive cases was high in the categories of adenocarcinoma, stage IV and large tumor size. Repeated measurements of serum CEA level was of value in the management of patients with lung cancer.View full abstractDownload PDF (550K) -
Nobuyuki Hara, Mitsuo Ohta, Takero Yoshida, Tsugio Furukawa, Kiyoshi I ...1983 Volume 23 Issue 5 Pages 595-604
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSWe carried out ventilation and perfusion scans in 52 patients with bronchogenic carcinoma and studied in detail (1) the relationship between regional pulmonary func-tion and regional ventilation-perfusion scans, (2) whether a corresponding correlation exists between ventilation-perfusion scans and the anatomic spread of the tumor and (3) whether ventilation-perfusion scans can predict anatomical resectability.
1) The correlation between oxygen uptake of each lung obtained from broncho-spirometry and ventilation-perfusion obtained from radioscan was excellent, the correlation being better for perfusion (r=0.95) than for ventilation (r=0.87).
2) The correlation between overall lung function, represented by FVC and FEV 1.0% and the ventilation-perfusion of the affected lung was poor.
3) Ventilation and perfusion scanning were useful in prediction of the overall lung function after pulmonary resection. The correlation coefficient between the predicted values calculated from ventilation-perfusion, and observed values postoperatively was between 0.85 and 0.89.
4) The relative ventilation and perfusion of the affected lung was changed in relation to the extent of tumor, indicating significantly lower values for stage III group than for stage I and stage II groups. The degree of reduction in ventilation-perfusion was closely related to the extent of compression and invasion of pulmonary vessels and bronchi by tumor in the hilum.
5) Evaluation of the regional ventilation and perfusion in the affected lung could provide preoperative information concerning resectability. When the relative ventilationperfusion of the affected lung was less than one third of the total, the tumor was found to be unresectable. When the relative ventilation-perfusion was 35-40% of the total, pneumonectomy was usually necessary and when the relative ventilation-perfusion was greater than 40%, a lobectomy was usually possible.View full abstractDownload PDF (5254K) -
Harubumi Kato, Chimori Konaka, Jutaro Ono, Norihiko Kawate, Kazuo Yone ...1983 Volume 23 Issue 5 Pages 605-613
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSSputum cytology can play an important role in the detection of central type early stage lung cancer. In this paper the results of sputum mass surveys in a new trial conducted through an educational TV program was described. The authors organized educational material concerning the role of sputum cytology for afternoon TV talk shows in 1980 and 1981. On the TV shows the importance of sputum cytology in high risk groups such as smokers, the frightening aspect of the disease and the possibility of cure in cases detected at an early stage were described. The programs were broadcasted throughout almost all Japan.
Sputum collection boxes were sent to those requesting them for an examination fee of $10. Sputum boxes were sent directly from candiates to the laboratory. The total number of candidates was 6, 820. The 4 cases of lung cancer detected were all males over 50 years old and heavy smokers. Sixteen other suspicious cases were finally diagnosed by fiberoptic bronchoscopy as severely atypical squamous metaplasia, bronchitis and other non-malignant diseases. Two of the cancer cases were radiographically occult cancers which were finally diagnosed as early stage central type lung cancer on the basis of fiberoptic bronchoscopy. The diagnosis was confirmed by examination of the resected specimen. The detection rate per 100, 000 examinees was 58.7. as compared to 10.3 per 100, 000 examinations in regular surveys of Tokyo Metropolitan Government employees and an overall incidence of 16 per 100, 000 examinees in the general population.
TV education is therefore an effective method to increase public knowledge concerning lung cancer. Sputum mass surveys promoted on TV are effective to detect earlystage central type lung cancer.View full abstractDownload PDF (6113K) -
The Possibilities and Limitations of PA AngiographyHiroshi Niwa, Takeo Mizuno, Shunzo Kobayashi, Hideki Ichimura, Kazuo S ...1983 Volume 23 Issue 5 Pages 615-626
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSEight cases of lung cancer involving the pulmonary venous root and left atrium were investigated. All cases received selective pulmonary artery angiography. The cases were divided into 2 groups according to the affected site of the pulmonary artery. Group A consists of cases with abnormalities in the segmental artery and group B consists of cases with abnormalities in the central portion such as the superior and inferior trunk. The findings of pulmonary artery angiogram consist of direct and indirect signs. Direct signs are stenosis and abnormalities of the distribution of the pulmonary vein opacified by contrast medium. Indirect signs include intact pulmonary artery in which involvement of the pulmonary vein is indicated, while the pulmonary vein is not opacified because of occlusion.
In group A (cases 1, 2, 6), 3 pulmonary veins were involved and all had direct signs. In group B (cases 3, 4, 5, 7, 8), 8 pulmonary veins were involved and 1 had direct signs and 3 had indirect signs.
Two cases received selective pulmonary artery angiography by inserting the catheter into the contralateral side pulmonary artery (contralateral side pulmonary artery angiography). In both cases tumor invasion and compression of the left atrium were shown by the contrast medium filled in the left atrium, because both superior and inferior pulmonary veins were occluded.View full abstractDownload PDF (17926K) -
Samon Miyata1983 Volume 23 Issue 5 Pages 627-635
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSEighty-three cases with small cell carcinoma of the lung were analyzed concerning tumor extent and effects of radiotherapy, chemotherapy from the point of view of survival and cause of death.
1) Limited type cases consisted of 53 cases (63.9%). and the extensive type 30 cases (36.1%).
2) One-year survival was 16/83 (19.3%), 2-year 5/68 (7.4%) and the median survival was 5.5 months.
3) Sensitivity to radiation was high and tumor regression was apparently obtained withdoses over 3000-rad.
4) The survival rate of 44 limited type cases receiving over 3000rad was 1 year in 15/44 (34.1%), 2 years 5/37 (13.5%) and the median survival months was 8.5 months. The one-year survival in 18 extensive type cases receiving over 3000rad was 5.6%, there was no two year survival, and median survival was 5.5 months.
5) Slight improvement was noticed with combined chemotherapy.
6) Distant metastasis caused death in 50% of cases and progressive chest tumor in 39%.View full abstractDownload PDF (916K) -
Koichiro Tatsumi, [in Japanese], [in Japanese], [in Japanese]1983 Volume 23 Issue 5 Pages 637-642
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSA 35-year-old asymptomatic male was admitted because of abnormal chest roentgenogram findings. Chest X-ray film showed a tumor shadow in the right lower lung field. Right lower lobectomy was carried out. The tumor in the right lower lobe (S10) was 4×3×3cm in size. Histologically, the tumor was oncocytomatous carcinoid.Electron microscopic findings showed oncocytoma cells packed with cytoplasmic secretion vesicles showing dense cores of varying size.
So far, very few bronchial oncocytoma have been reported. The clinicopathological features of oncocytoma are discussed.
So far, very few bronchial oncocytoma have been reported. The clinicopathological features of oncocytoma are discussed.View full abstractDownload PDF (6143K) -
Soji Ishikawa, Keizo Tomiki, Shigeki Ishihara, Keiko Inatomi, Hiomi Ho ...1983 Volume 23 Issue 5 Pages 643-649
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSA patient underwent segmentectomy of the superior portion of the right lower lobe after upper lobectomy of the same lung for primary bronchogenic carcinoma. This patient is disease-free 7 years after the limited operation.
We considered this case as a reasonable indication for curable limited operation because he had good immunocompetence, a solitary nodular lesion with no regional lymph node metastasis or distant metastasis.View full abstractDownload PDF (7890K) -
[in Japanese]1983 Volume 23 Issue 5 Pages 651
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSDownload PDF (87K) -
[in Japanese], [in Japanese], [in Japanese], [in Japanese], [in Japane ...1983 Volume 23 Issue 5 Pages 653-657
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSDownload PDF (7019K) -
1983 Volume 23 Issue 5 Pages 659-662
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSDownload PDF (426K) -
1983 Volume 23 Issue 5 Pages 663-678
Published: December 25, 1983
Released on J-STAGE: August 10, 2011
JOURNAL FREE ACCESSDownload PDF (2193K)
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