日本ハンセン病学会雑誌
Online ISSN : 1884-314X
Print ISSN : 1342-3681
ISSN-L : 1342-3681
67 巻 , 3 号
選択された号の論文の2件中1~2を表示しています
  • 石田 裕, Ajoy Kumar BISWAS, Sr. Elena Guglielmelli
    1998 年 67 巻 3 号 p. 391-400
    発行日: 1998年
    公開日: 2007/11/30
    ジャーナル フリー
    The early case detection followed by WHO/MDT is the most important in leprosy control program not only for the destruction of linkage of infection but also the prevention of disability in leprosy. PIME Sisters leprosy program has been carrying out active case detection for leprosy since 1986 in Khulna, the third biggest metropolitan city in Bangladesh.
    The relation between several detection modes and their associated disability grading was analyzed in order to see the contribution of each detection mode to disability grading.
    The disability grading of new registered patients from 1995 to 1997, 1, 115 cases in total was analyzed according to its detection mode.
    Voluntary reporting patients from “out of control area” had both high disability grading of G=2 (38.0%)and high MB rate (39.3%). On the other hand voluntary reporting paticnts in control area had less disability grading of G=2 (12.2%)and less MB rate (25.3%). The number of patients referred by local doctors was still small and had both high disability grading of G=2 (27.0%)and high MB rate (51.4%). Children detected under school surveillance did not have any marked disability of G=2 (0%)and were almost PB patients (88.6%). (Prevalence rate of school surveillance was low.) Patients detected under general surveillance had low disability grading of G=2 (2.6%). The disability grading (G=2) of voluntary patients from control area (12.2%) was three times as much as that of patients from general surveillance (2.6%). Lastly patients of family contacts who were aware of the first symptoms had relatively less disability grading (5.9%).
    The small number of patients referred by local doctors (3.3% of total number) with high disability grading meant that there would be still great need of information programs on leprosy for local medical professions to think about leprosy. The high disability grading of patients from “out of control area” meant that the more effective leprosy control program should be done in “out of control area”.
  • 和泉 眞藏, Teky Budiawan, 松岡 正典, 佐伯 圭介, 川津 邦雄
    1998 年 67 巻 3 号 p. 401-408
    発行日: 1998年
    公開日: 2007/11/30
    ジャーナル フリー
    ハンセン病の疫学に関する研究における最も重要な未解決課題の1つは、病気の不均一な地理的分布である。流行国には“pocket”と呼ばれる濃厚流行地域があるが、なぜその地域でハンセン病が多発するのかはほとんど解明されていない。われわれは、血清学的手法と分子生物学的技術を用いて、pocketにおける一般住民のらい菌感染状況と生活環境中のらい菌の分布に関する疫学調査を行い、地理的不均一分布の原因の解明と、ハンセン病の予防対策に必要な基礎資料の収集を試みた。その結果、濃厚流行地においては、生活環境中にらい菌が存在し、多数の一般住民がらい菌の感染を受けている事実を発見した。これらの事実は、地球的規模でハンセン病を制圧するためには、患者のみを対象とした多剤併用療法の普及では不十分で、発病危険感染者に対する予防投薬などの新しい原理に基づく予防対策が不可欠であることを示唆している。
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