Embryonic stem (ES)cells are pluripotential cells, and enable us to study mechanisms of cell differentiation. Gene disruption of ES cells by homologous recombination is to be clear the function of targeted genes. Recently, it has been reported that bone marrow hematopoietic stem cells have a potential to differentiate into neuronal cell, muscle cell, liver cell, epidermal cell, and also epithelial cell lineages. Moreover, cloned animals from somatic cell nuclei were produced. Here, we show osteoclastogenesis, and endothelial cell-genesis from single ES cell, and discuss the possibility for organogenesis in vitro. Furthermore, we would like to summon to understand usefulness and dangerousness of the regenerative medicine.
The Leprosy Prevention Law was abolished at the end of March, 1996. Since medical insurance for leprosy started in April, 1996, dermatologists in clinics have to take care of leprosy patients. However, dermatologists have not learned enough about leprosy, and only a few of them are familiar with it. Japanese patients newly diagnosed with leprosy in Japan have decreasing, and patients who come from foreign countries to work in Japan have more important in leprosy control. Therefore, it is important to educate dermatologists about leprosy. Recently, diagnostic guides including information about network systems have become available in book stores. It is possible to obtain all kinds of information about leprosy from the network systems.