In conjunction with our study concerning time-course analysis of language function in aphasics, we made a broad examination of the following existing reports..
We investigated long-term follow-up data for lesions of 270 right-handed aphasics with left lateral damage. We also studied 37 aphasics whose language functions declined in their general scores on the Standard Language Test of Aphasia (SLTA), examining functional change in the various factors affecting those scores. We then compared the function maintenance group with the functional decline group. Function maintenance was seen in 36 cases showing no decline in language function over the long term. We exam ined the progress of lower items irrelevant to SLTA general scores of both groups. Furthermore, in 248 aphasics we investigated factors that have an influence on the general scores of SLTA, which serves as an indicator of function recovery.
The results were as follows.
1) Depending on the lesion site and age at onset, recovery of aphasia symptoms varies in course greatly; however, many aphasic cases show recovery over long terms of at least six months or more.
2) Functional restoration of language by therapy is not stable but rather fragile.
3) Some lower items that are not related to general scores on SLTA supplement general scores on SLTA. We postulate that these can serve as indicators of changes in the aphasia symptoms. The items are “following oral commands,” “sentence repetition,” “word finding” and “kanji writing.”
4) The lesions that influenced prognosis were as follows: insula, postcentral gyrus, middle temporal gyrus and inferior temporal gyrus. The presence or absence of the following diffuse lesions was related also: cortex atrophy and lacunar infarction.
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