近年，骨髄非破壊的移植の開発により，高齢患者の移植が増加している。2事例の高齢患者の看護を振り返り，今後の課題について検討した。その結果，高齢患者が移植を受ける際は，患者の価値観や希望を尊重しつつ様々なリスクを予測したうえで，多職種の医療チームにより移植適応の可否を適正に評価する必要があり，看護師は患者や家族の理解度を把握した上で意思決定支援を行っていかなければならないことが明らかとなった。今後は，看護師は移植前から多職種との連携や調整におけるリーダーシップをとり，患者や家族の価値観や希望を医療チームで支えていく体制を整える必要がある。

 Our policy has been to administer granulocyte colony-stimulating factors (G-CSF) for the mobilization of peripheral blood stem cells (PBSC) on an outpatient basis. We evaluated the safety of G-CSF-administered PBSC donation in outpatients and inpatients. Subjects : PBSC donations from 86 healthy donors (78 related, 8 unrelated) between January 2011 and December 2019 were included; 74 donors were administered G-CSF as outpatients, and 12 while under hospitalization. Evaluation of the length of hospital stay (LOHS) : LOHS of the donors who were administered G-CSF as outpatients (median, 2 days; range, 1 to 4 days) was significantly shorter than that of the inpatient donors (median, 4.5; range, 4 to 5) (P<0.0001). Adverse events of G-CSF administration : There was no significant difference in the incidence of adverse events related to G-CSF administration between the donors who were administered G-CSF as outpatients and those as inpatients (P=0.1786). Efficacy of PBSC mobilization : Most donors donated sufficient PBSC (median CD34⁺×10⁶ cells/kg recipient body weight, 5.65). There was no significant difference in the number of collected CD34⁺ cells between the two groups (P=0.6671). Conclusion : Outpatient-based administration of G-CSF for PBSC mobilization was feasible without compromising donor safety or PBSC donation efficacy.