This study was carried out to clarify the inhibiroty effects of the powdered semiconductor TiO
2 with a photocatalytic reaction on oral cariogenic streptococci by cyclic voltammetry. Three bacterial strains (Streptococcus mutans NCTC 10449, S. mutans NCTC 10449, S. cricetus HS-6, S. sobrinus AHT) were suspended in phosphorous buffer solution (pH 7.0) containing TiO
2 (0.1% W/V) powder. Oxidation peak current (Ipa) and potential (Epa) of the anodic peak in TiO
2-bacterial solutions were measured by cyclic voltammetry. Strains of streptococci showed different Ipa but there was no marked difference in the Epa. Cyclic votlammograms of TiO
2-bacterial solutions were different from those of control samples without TiO
2; Ipa decreased markedly, while Epa showed no marked change. Specific adsorption behavior of these bacteria to TiO
2 was observed by scannning electron miroscopy.
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