The 24-hr urine was collected for five days from five adult men working in the laboratories of School of Health Sciences, University of Tokyo. The urine volume and contents of creatinine (CN), lead (Pb), cadmium (Cd), delta-aminolevulinic acid (ALA) and coproporphyrin (CP) were measured daily.
(1) The inter-individual variation was statistically significant in the daily amounts of CN, CP and ALA, the urinary concentration of Pb, and the corrected concentra-tions with CN for CP and ALA by the analysis of variance.
(2) In the daily amount of excretion, the metals and the urine volume were statisti-cally significantly correlated each other, but ALA is significantly correlated to CN and CP, and CP is only to ALA.
(3) The individual average of the number of cigarettes per day had the significant values in the rank correlation coefficients to the urine volume, the corrected concen-tration of ALA, the corrected concentration of Pb, the daily amount of Pb per unit of body weight, the daily amount of Cd, the corrected concentration of Cd, and the daily amount of Cd per unit of body weight.
By the results, the role of cigarettes smoking was discussed in relation to the urinary excretion of the metals.
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