Japanese Journal of Medicine

Japanese Journal of Medicine

Online ISSN : 1881-123X
Print ISSN : 0021-5120

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Volume 18, Issue 4

Displaying 1-12 of 12 articles from this issue

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Calcium Metabolism during Corticosteroid Therapy

Takuo FUJITA, Masashi MORIYAMA, Asami UEZU, Kiichiro Ota, Masahiko OHA ...

1979 Volume 18 Issue 4 Pages 285-289
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.285

JOURNAL FREE ACCESS

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In order to elucidate the mechanism of derangement of calcium metabolism in patients under corticosteroid therapy, serum calcium, inorganic phosphorus, creatinine, alkaline phosphatase and parathyroid hormone (PTH) and urinary calcium, phosphorus and creatinine were measured and tubular reabsorption of phosphorus (%TRP) calculated in 20 patients before and during corticosteroid therapy up to 6 months. Serum calcium was significantly lower and serum PTH significantly higher in patients under corticosteroid therapy than those without it. During the course of corticosteroid treatment, serum calcium was significantly below the control level after 2 months of treatment, while urinary phosphorus excretion rose and %TRP fell significantlp after 6 months. These data would indicate a tendency of corticosteroid-induced hypocalcemia and secondary hyperparathyroidism with hyperphosphaturia in patients under corticosteroid therapy.

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Serum and Hepatic Alpha-1 Antitrypsin in Adult Liver Cirrhosis

MA SIDDIQUI, AM Kazim KAZA, KN AHMAD, AK ABDULLAH, Ch RU KHAN

1979 Volume 18 Issue 4 Pages 290-294
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.290

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Serum Trypsin Inhibitory Capacity (STIC) was measured in 50 healthy subjects and 50 adult cases of biopsy proved cirrhosis of the liver. Liver biopsy of all the 50 cirrhosis cases were examined for intracellular deposits of alpha-1 antitrypsin (AAT) in the form of intracytoplasmic PAS-positive diastase resistant globules. STIC was found normal in all the controls and 37 cirrhotics. Eight cirrhosis cases had intermediate (heterozygous) deficiency and five had severe (homozygous) deficiency. PAS-positive globules were found in all the five cases with homozygous AAT deficiency but in none of the others. There appears to be a strong association of cirrhosis with both heterozygous and homozygous AAT deficiency, although AAT deposits in the liver may not be present in heterozygous cases. The possible mechanism of the association of cirrhosis with AAT deficiency has been discussed.

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Respiratory Care

Hitoshi NAGANO, Hajime YAMABAYASHI, Shinichi TANIMOTO, Kazushige FUJIT ...

1979 Volume 18 Issue 4 Pages 295-315
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.295

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Review on Internal Medicine, 1978

Cerebrovascular Diseases

Tadao Tsubaki

1979 Volume 18 Issue 4 Pages 316a
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.316a

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Introductory Remarks

Yasushi Ueda

1979 Volume 18 Issue 4 Pages 316b
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.316b

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(1) Pathogenesis of Cerebral Infarction - A Clinical and Pathological Study

Masakuni Kameyama

1979 Volume 18 Issue 4 Pages 316c-319
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.316c

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(2) Cerebral Circulation and Autonomic Nervous Function in Cerebrovascular Disease

Fumio Gotoh

1979 Volume 18 Issue 4 Pages 319-320
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.319

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Supplimentary : Thrombolytic therapy using urokinase on cerebral thrombosis

Nobuo SAKURAGAWA

1979 Volume 18 Issue 4 Pages 321-322
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.321

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(3) Cerebrovascular Diseases in Young Adults

Sadatomo SHIMOJO

1979 Volume 18 Issue 4 Pages 322-323
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.322

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(4) Diagnostic Problems of Acute Cerebrovascular Stroke

Yoshiaki TAZAKI

1979 Volume 18 Issue 4 Pages 323-325
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.323

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(5) Correlation of Computed Tomography and Autopsy Findings of Cerebrovascular Diseases

Hitoshi FUKASAWA

1979 Volume 18 Issue 4 Pages 325-328
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.325

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Closing Remarks

Tadao TSUBAKI

1979 Volume 18 Issue 4 Pages 329-330
Published: 1979
Released on J-STAGE: March 27, 2006

DOIhttps://doi.org/10.2169/internalmedicine1962.18.329

JOURNAL FREE ACCESS

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