医療
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
18 巻, 7 号
選択された号の論文の14件中1~14を表示しています
  • 布施 信良, 長田 博之, 大岡 譲
    1964 年 18 巻 7 号 p. 417-422
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
  • 加藤 明, 浅子 由己, 佐藤 宏, 迎 巌, 堀部 寿雄
    1964 年 18 巻 7 号 p. 423-429
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
    In Narashino National Hospital the occurrence of hepatitis after blood transfusion has been increasing from 3.1% (1962) to 10.4% (1963), and these cases required much longer period of medical care for hepatitis than the original disease, so that the early discovery of the illness, keeping rest and immediate treatment are very important, and follow-up study of GPT or BSP test for the patients are desirable.
    In 1963, we experienced 3 cases of hepatitis by only “one bottle blood transfusion.” This “one bottle blood transfusion” occupies 19.1% of all cases administered blood transfusion in our hospital. Therefore a small amount of blood transfusion should be evaluated for it's necessity before administration.
    There are reports to prevent hepatitis by means of exclusion of higher titer one by measuring GPT of blood before it's transfusion. Follow up study of this method at our hospital showed high titer in 28.5% of blood.
    Because of no specific simple test is available to detect viral hepatitis at present, it is practical method to measure GPT of preserved blood to exclude the higher titer one and to prevent hepatitis.
    To supply the blood to blood bank, the donor on commercial base as at present in Japan is not desirable and establishment of the system to supply blood by healthy person is urgent problem.
  • 天羽 道男, 菊地 敬一, 島田 敏雄, 浜野 三吾, 加納 保之
    1964 年 18 巻 7 号 p. 430-434
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
    Analysis of cases with postoperative liver dysfunction encountered in 320 cases of chest surgery during January, 1961 through May, 1963, revealed as follows:
    1) Incidence of postoperative liver dysfunction was found to be ca. 40% during this period.
    2) Every year the incidence increased slightly and reached 56.3% in 1963.
    3) Jaundice was found to develop in about 10% of the postoperative cases in each year.
    4) Higher incidence was found in patients with advancing severity according to N. T. A. classification of Tbc.
    5) Amount of blood transfusion could also be related with higher incidence.
    6) The liver dysfunction was detected in ca. 90% of the cases within 3 months after the surgery.
  • 小嶋 紀, 長野 英世, 中村 博, 鈴木 司
    1964 年 18 巻 7 号 p. 435-438
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
    In the liver biopsy the Vim-Silverman needle has been widely used in this country. In 1958 a new biopsy instrument was introduced by G. Menghini in Italy, Twenty-four biopsies were performed by means of this needle and were compared with that of the Vim-Silverman.
    The Menghini needle is recommended by the reason of the simplicity of instrument, easy procedure, efficiency of success and reducing accidents.
    Some disadvantages were discussed.
  • 園田 憲章
    1964 年 18 巻 7 号 p. 439-444
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
    For discerning the abnormal coagulability related to abnormal bleeding or thrombosis, 1) tourniquet test (Rumpel-Leede phenomenon), 2) thrombotest (Owren), 3) one-stage prothrombin time (Quick) and 4) measurement of the plasma fibrinogen level were performed. 29 cases of liver disease, 19 cases of diabetes mellitus, 12 cases of chronic nephritis and 13 cases of biliary tract disease were subjected to the above examinations.
    Then the above tests were performed before and after administration of ε-aminocaproic acid which is an anti-fibrinolytic agent. The results obtained are as follows:
    1) Although tourniquet tests were positive in most cases of each group, liver disease and diabetes mellitus were moderately to highly positive.
    2) Blood coagulation tested by thrombotest and prothrombin time diminished in most cases of liver disease, and few cases of which diminished markedly.
    Although some cases of chronic nephritis and biliary tract disease slightly decreased in coagulability, in most cases, especially of diabetes mellitus were normal or perhaps increased.
    3) Plasma fibrinogen level decreased in some cases of liver diseae, wherease in others increased. In the other groups of disease, however, it showed almost exclusively increased tendcrcy.
    4) As to the effect of ε-amino-caproic acid on liver disease and the others,
    i) negativation of positive tourniquet test, ii) increased value of thrombotest, iii) decreased prothrombin time associated with decreased Plasma fibrinogen level were observed.
    Conclusion:
    1) Hypocoagulability associated with the damage of small vessels as seen in liver disease may induce abnormal bleeding, whereas hypercoagulability as seen in diabetes mellitus would produce thrombosis.
    2) As shown by the effect of ε-amino-caproic acid, hypocoagulability in liver disease would be based on accentuation of fibrinolysis (proteolysis).
  • 菊地 金男
    1964 年 18 巻 7 号 p. 445
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
  • 出野 秀
    1964 年 18 巻 7 号 p. 446-449
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
    Up to date the cases of serum hepatitis are remarkably increasing and its outbreak rate amounts to over 30 per cent including the non-icteric cases.
    The incubation period is shown from 30 to 180 days in most reports. It has been considered that the prognosis in this disease was regarded as favourable, however, one could not be so optimistic because the serum hepatitis could be predisposed to the chronic hepatitis and cirrhosis of the liver.
    The indication of the blood transfusion has to be scrutinized because of following-up the donors who make apparently the recipient to fall ill is usually in vain so as to point out the infectious sources.
  • 橋上 保二, 木野 喜郎
    1964 年 18 巻 7 号 p. 450-454
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
  • 太田 藤市郎, 崎田 文寿, 高橋 達男, 市原 靖, 三田 盛一, 橋本 敏夫
    1964 年 18 巻 7 号 p. 455-460
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
    We experienced 34 cases of serum hepatitis in recent 5 years and 36 cases of epidemic hepatitis in 3 years, and compared the 2 types mainly from clinical standpoit.
    1) Among serum hepatitis, 27 cases (79.5%) were accompanied with jaundice (21 surgical cases and 6 non-surgical) and 7 cases (20.5%) were not accompanied with jaundice. In epidemic hepatitis 21 cases were male, 15 cases were female and the predilection age was between 2 to 4 decades.
    2) As the initial cardinal symptoms, fever, nausea and vomiting were few in serum hepatitis, hepatomegaly and itching were equal in each groups, but splenomegaly was rare in either one.
    3) The incubation period was 26 to 100 days but the majority was in 90 days and somewhat longer in epidemic hepatitis.
    4) The amount of blood transfusion was 200 to 9, 600cc, the number of transfusion was 1 to 24 times, and the majority was 1, 000 to 1, 500cc (5 to 7 times), All cases received preserved blood, except one case who received preserved blood and dried plasma.
    5) As to the liver function test, on initial examination no difference was found in both hepatitis, but on follow-up study of the cases the serum treansaminase and alkaline phosphatase were somewhat higher in serum hepatitis.
    6) Prolonged impairement of liver function was found in 29.4% of epidemic hepatitis and in 46.4% of serum hepatitis.
  • 檜山 輝男
    1964 年 18 巻 7 号 p. 461-469
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
    The liver function test, urinalysis and C. B. C. were carried out before and after blood transfusion, with respect to occurrence of posttransfusion hepatitis. The next our study aimed that the posttransfusion hepatitis might be related to infection of B-Virus on the bases of allergic reaction of liver, so that this hepatitis could be prevented by administration of anti-allergic agents (antihistamines) into stored blood before starting transfusion.
    The laboratory findings of the cases of hepatitis were as follows;
    1) Positive Kunkel's reactions were much observed before administration of blood transfusion, 2) many cases showed elevated icteric index 3 weeks after transfusion, 3) many cases presented increased value in S-GOT, and B. S. P. 1 and 3 weeks after transfusion, 4) C. C. F. reaction became abnormal 3 weeks after transfusion in a majority of cases, 5) there was a tendency of leucopenia and eosinopenia 3 weeks after transfusion, 6) many cases showed positive urine urobilinogen reaction before transfusion and 7) the histological findings of the liver, which were partly removed during operation, disclosed fibrosis, dilatation of the biliary duct and thickness of capsule in many cases.
    Strong minophagen C and chlortrimeton were used as anti-allergic agents in order to prevent the recipient from getting the posttransfusion hepatitis. The study has been done in the following groups; a) the control, b) the group received strong minophagen C (M. C.); c) the group received chlortrimeton (Cl-T). d the group received both M. C. and Cl-T. (G). In the ratio of occurrence of posttransfusion hepatitis, Cl-T, group was the least of all, As to the liver function test, Cl-T group was much effective to prevent C. C. F. value abnormality, but G. group was more effective to minimize S-GOT and S-GPT elevation than the others.
  • 中野 昭二, 鳥居 有人, 宮里 良康, 木下 広明, 千島 雅太郎
    1964 年 18 巻 7 号 p. 470-475
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
  • 原 健夫, 味木 稔, 原田 信徳, 大田 暁
    1964 年 18 巻 7 号 p. 476-479
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
    With the wide application of liver biopsy, laparoscopy and liver function tests, the attention is being focused on the presence of congenital jaundice defined as Gilbert's Disease or Dubin-Johnson's Syndrome, which heretofore have been treated as chronic hepatitis. A number of case reports are being presented on this subject recently. As this author and his associates have recently observed 2 cases which were believed to be Gilbert's Diseae from their peculiar clinical course, they will be introduced hereunder.
    Case 1 was a 37-year-old female who complained of general malaise, exertional fatigability and dull aching in the right upper quadrant. She had received treatment under the diagnosis of chronic hepatitis or gall bladder disease. Her findings at the time of examination were not remarkable with the exception of slight yellowing of the conjunctiva and palpable liver and right kidney, the former at 2 finger breadths.
    During the course of treatment, it was found that on exertion liver function tests fluctuated and degree of jaundice became severe. From these findings Gilbert's Disease was suspected, but the final conclusion was reached after liver biopsy and laparoscopy.
    Case 2 was a 16-year-old boy whose complaint was severe yellowing of the conjunctiva. As there was evidence of a familial history, examination of as many family members as possible was performed. Jaundice was noted and the values of indirect bilirubin were elevated in all family members seen.
    On the other hand, BSP values of 7% and 9% were demonstrated and findings which resemble Dubin-Johnson's Syndrome were observed, such as poor visualization on cholecystography, but due to circumstances on the side of the patient, liver biopsy and laparoscopy could not be performed. The finding that the values of direct bilirubin were not elevated led us to believe that it would be rea sonable to conclude this to be a case of Gilbert's disease.
  • 伊藤 典夫
    1964 年 18 巻 7 号 p. 480-486
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
    K, Mg-Aspartate (Aspara-Tanabe) was administered to 10 cases of liver disease at the dosage of 9-21 tablets daily for 24-176 days, combined with other liver protecting agents and the following results were obtained:
    1) Out of 10cases, the effects were excellent in 3cases, good in 4cases and fair in 3cases.
    2) It is noteworthy that the 2 patients of chronic hepatitis, in whom prolonged administration of other liver protecting agents gave only slight effects, were improved after the combined treatment with Aspara.
    3) In no cases any side effects of Aspara were observed.
  • 寺畑 喜朔
    1964 年 18 巻 7 号 p. 487-488
    発行日: 1964/07/20
    公開日: 2011/10/19
    ジャーナル フリー
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