This was subjected on mothers and their babies who had been admitted to the 2nd Tokyo National Hospital during the period of 1957 through 1962.
All mothers had full term of pregnancy without any complication. Among the newborn infants, prematurity, postmaturity, twin and deformity are excluded. At the time of birth, O₂ and CO₂ content in the blood of navel cord were estimated. Those infants and children had been observed by measuring of weight, height, time of eruption of tooth and mental test periodically for four years after birth.
As the conclusion:
1) The main suppressive factor to the physical development of the newborn infant was hypoxia at the ante partum, partum and post partum. The narcosis and caesarean section were found to be the suppressive factor to some extent.
2) The main suppressive factor to mental development of the newborn infant was hypoxia at the antepartum, partum and postpartum, but the narcosis and caesarean section were not to be suppressive factor.
3) Either to the narcotic and non-narcotic delivery, it is important to give oxygen inhalation to mother at birth and then to newborn to avoid hypoxia.

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It is considered that N₂O-anesthesia with Thiamylal and S. C. C. is safe for both mother and baby in cesarean section, while Fluothane anesthesia is contra in dicated because of the matter of sleeping baby and disturbance of uterin contraction.
However, we have obtained the following good results that G. O. F.-anesthesia makes no side effect for both of them.
It is the most important point in G. O. F.-anesthesia that after induction Fluothane is not to be used before expulsion but after birth to be used in 0, 5-1.0 per cent.
General anesthesia was employed for 42 cesarean section, in which N₂O-anesthesia 28 and G. O. F.-14. The average Apgar's score is 6.3 in the former case and 8.1 in the latter. These results suggest that G. O.F.-anesthesia may be more valuable than N₂O.
In our case, G. O. F, -anesthesia has brought as good uterine contraction without atonic hemorrhage as N₂O. It is the best method that we can find for cesarean section.

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In order to investigate the transition of plasma histamin in tuberculous rabbits, cortison only and cortison in combination with streptomycin or isoniazid were administered.
The results obtained are as follows;
1. By the administration of cortison to tuberculous rabbits, amount of plasma histamin were decreased and tuberculous lesions were worsend with decrease of tuberculin reaction.
2. By the administration of cortison in combination with streptmycin or isoniazid to tuberculous rabbits, amount of plasma histamin were decreased and tuberculous lesions were improved with decrease of tuberculin reaction.

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1. From 1959 through 1963, 97 patients were seen at our hospital because of elbow fracture and/or dislocation. Seventy (72 percent) of these were seen at follow-up.
The age of patients ranged from 1 to 15 years. Male left elbow are predisposed. Most common causes are a fall from bicycle (10 cases), from tree (10 cases), during gymnastic on the bar (16 cases) and fall down while playing (15 cases).
2. Seventy patients are as follows:
There are 31 fresh (15 closed treat. & 16op. treat.) & one old op. treated supracondylar fr., 14 fresh (7 closed treat. & 7op. treat.) and 4 old (2 closed treat. & 2op. treat.) lat. cond, fr., 4 fresh (3 closed treat. & 1op. treat.) and 2 old closed treated med. cond. fr., 3 fresh (2 closed treat. & 1op. treat.) & 2 old op. treated dislocation and/or fr. and 9 fresh (6 closed treat. & 3 op, treat.) other type of fractures.
(Fresh: treated with in 2 weeks after injury. Old: treated after 2 weeks after inyury.)
3. one to seven years follow-up after injury are as follows:
(1) In five of thirty two patients of supracondylar fracture and two of eighteen patients of lateral condylar fracture the range of flexion motion were not complete with restriction ranged from 60 to 90 degrees.
(2) The incidence of changes in carrying-angle after supracondylar fracture are 58 per cent. Of thirty-one patients (fresh fracture), sixteen (52 per cent) showed decreasing in carrying-angle. of these sixteen patients, seven (23 percent) were enough to be called Gunstock deformities (8 to 27 degrees). Of thirty-one patients, two (6 per cent) showed increasing (5 degrees) in carrying angel. The incidence of that changes after lateral condylar fracture are 50 percent. of fourteen patients (fresh fracture), four (28 percent) showed decreasing in carrying-angle. Of these four patients, two (14 per cent) showed Gunstock deformities (6 to 27 degrees). Of fourteen patients, three (21 per cent) increased in carrying-angle (5 to 12 degrees).
Such a changes, decreasing and increasing, in carrying-angle after the other type of fractures were noted one patient respectively.
(3) The elongation of condylar line with enlarged lower end of humerus ranged from 2 to 10 milimeters with the average of 4 milimeters.
(4) Two of eighteen. patients of the lateral condylar fracture and two of eighteen patients of the medial condylar fracture were showed non-union respectively.
(5) Only one patient of supracondylar fracture had nerve damage; This patient showed signs of claw hand on admission. Recovery had not occurred when he was seen for follow up one year later. The other one patient of supracondylar fracture was noted miositis ossificans with restriction of motion.

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Anabolic steroids were given to the far advanced pulmonary tuberculous patients with multiple cavities and positive tubercle bacilli in sputa. Daily dosis of 20mg of oxymetholone (HMD) were given to one female and 9 male patients, 6mg of 17α-ethylestrenol (EHE) to one female and 9 male patients and the placebo to 5 male patients for 18 weeks. They were all given the antituberculous drugs and aminoacid preparation.
Nitrogen balance (Fig. 1) showed positive results in both HMD and EHE group after the administration. Body weight was increased at 4 weeks after the administration (Fig. 2, Table 1) and thereafter the increasing rate was lower (wearing off phenomenon). Erythrocyte sedimentation rate was much improved after a month (Fig. 3), and after the cessation of steroids it became faster again.
Serum cholesterol level was lowered markedly in both groups (Fig. 4, Table 2). BSP retention after 30 min (Fig. 5, Table 3) was increased during the treatment and recovered to normal value 2 weeks after the cessation. Serum GOT and GPT activities were increased in 4 patients in HMD group and 4 patients in EHE group, but none in the placebo group (Table 4). PZM or 1314TH which might induce the liver damage did not show such a high frequency of liver damage in tuberculous patients. HMD and EHE increased slightly the basal metabolic rate (Fig. 6).
In the present series of experiments there were no definite tendency in the balance of Ca and P, hemoglobin content, RBC, WBC, serum and urinary Na, K, Cl, creatine and creatinine, urinary 17-KS and 17-OHCS, and the blood sugar level.
Roentogenographic examination of the chest showed the slight improvement in one patient and the aggravation in one patient of HMD group, and two improved cases and one aggravated case in EHE group, but no change was seen in the placebo group. In both HMD and EHE group the tuberclebacilli in sputa disappeared in each two patients, but were always positive in control group.
As the sids effects the liver damage, headache, abnormal taste in the mouth, gynecomastia, acne, hoarseness, hirsutism, etc. were noticed (Table 5). Number of the side actions was more in HMD group than EHE group, because the dosis were greater in HMD group. Appetite and weakness were improved.

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This subject was experimented with H₃₇Rv strain and Inouestrain isorated from sputum of pulmonary tuberculosis patient treated with Cycloserine (CS) previously. Strains were cultured on 1% Ogawa's egg slaut for 3 weeks. Following results were obtained.
1) The minimal inhibitory concentration of CS to H₃₇Rv strain on the resistance media used immediately after adjustment was 10 mcg/ml when it was cultured for 3 weeks on 1% Ogawa's egg slaut. And it was also 10mcg/ml when it was cultured for 2 weeks on Kirchber's semi-liquid agar media. It was 20mcg/ml when it was cultured for 4 weeks on 1% Ogawa's egg slaut as well as when it was cultured for 3 weeks on Kirchner's semi-liquid agar media.
2) Both the case when the media was preserved in a refrigerator at 5°C and the case when it was incubated at 20°C, the anti-tuberculous strength of CS was inclined to fall according to the postponement of preservative period on both media.
3) When they are preserved in a refrigerator at 5°C; The inhibitory power of CS to mycobacterium tuberculosis was equal to the biginning with in 4 weeks after adjustment on 1% Ogawa's egg slaut and within 2 weeks on Kirchner's semi-liquid agar media.
When they are incubated at 20°C; It was equal to the beginning with in 1 week on 1% Ogawa's egg Slaut. and with in 2 weeks on Kirchner's semi-liquid agar media.

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We studied the results of 3, 126 pulmomry tuberculous cases surgically treated in 24 national sanatoriums. 93.2% of the total cases were treated by lung resection of thoracoplasty. The younger a patient was the more resection was performed, and thoracoplasty was prefered for rather older patients. Resection was performed as many as thoracoplasty in patients of 50 to 55 years of age in this study, but this zone of age tends upwards. Average life after surgery of patients over 60 years of age was remarkably shorter compared with that of younger patients. It is emphasized that various factors should be collected and judged comprehensively in order to decide surgical indication for aged patients.
The utmost care must be taken in surgery of aged patients for safety and secure post operative treatment. We should recognize that apresent aim of surgery for pulmonary tuberculosis has been changed from life saving to rehabilitation, and we must perform surgical treatment with consideration for patients' individual and social conditions.

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This survey was conducted in April 1965 by home-visit interviews on prognostic conditions of twenty-two schizophrenic patients who now live in Ichikawa City and had been discharged from Jan., 61 to Dec., 61.
The prognosis of these patients is unfavorable: Out of twenty two cases, ten are now hospitalized, five are mal-adlusted and seven patients are well-adjusted.
Althogh the degree of progress of schizophrenic process should be regarded as one of the causes of this result, the following factors were assumed to be effective conditions for prognosis of schizophrenia. That is, the age at the onset of schizophrenia, the time of starting psychiatric treatment, the recurrent conditions, sub-type of schizophrenia, ways of having contact with hospital and understanding of closed others, which were infered as factors that effect the prognosis of schizophrenia.
Treatment planning fo rschizophrenia must be based on consideration with the complicated interaction of these factors.

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The following are the present results as to Gnathostoma doloresi Tubangui, 1925, which is parasiticon Sus scrofa leucomystax.
1) 3 _??_ found out of 1, captured in Gunlyo-gun, were the first finding in Gifu-ken.
2) 1_??_ was found out of 1 in Naka-gun, Tokushima-ken.
3) Parasites were found in 61 out of 66 in Kikuchi-shi, Hitoyoshi-shi, Minamata-shi, Kikuchi-gun, Aso-gun, Kamimashiki-gun, Shimomashiki-gun, Yatsushiro-gun, Kuma-gun and Ashikita-gun, Kumamoto-ken. Maximum finding out of 1 was 66 in Aso-gun.
4) 3 were found out of 1 among 2, captured in Nishiusuki-gun, Miyazaki-ken. 6 out of 1 captured in Koyu-gun.
5) 1 and 20 were found out of 2 among 2, captured in Oguchi-shi, Kagoshima-ken.

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1) This special Skin Clinic in Nagoya, Aichi, has been held by the authors for the past two years.
2) The purpose of this Clinic is to follow up discharged patients from the leprosarium and to take care of those coming from the sanatorium when the time of returning home has expired.
3) This clnic is opened every three months and the officer of the Prefectual office announces the date and time of the patients arrival. 4) This clinic is not recognised yet officially, but the patients are increasing at each opening. This proved that they feel actually the need of such a clinic.

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