During 17 years from 1950 through 1966 we have experienced 22 cases of multiple myeloma which were confirmed by post mortem examination, tumor biopsy, bone marrow puncture and serum protein fraction by electrophoresis. Among them male cases were 14 and female were 8. They were all above fourth decade except one 29-year-old male and mostly between sixth and seventh decade.
Initial symtoms and signs were mostly lumbago, backache and headache, then general malaise, palpitation and tinnitis etc. due to anemia. Some cases had had chief complaints of nausea, blurred vision and hemorrhagic tendency.
R. B. C. were 2 to 3 million/ccm in male and 1 to 2 million/ccm in female. W. B. C. ware 2, 000 to 6, 000/ccm, in which lymphopenia, granulocytosis and below 1 to 2% of plasma cells in peripheral blood, , except of one case who had 12%, whereas plasma cells in bone marrow varied between 3 to 98%. Serum protein were 5.0 to 14.0g% with 7.3 to 84.0% of γ-globulin.
E. S. R. were usually accelerated over 100mm in one hour.
Albuminuria were found in 16 cases with 7 cases of positive Bence-Jones protein.
E. K. G. revealed non-specific ST, T change generally, but few cases showed A-V conduction defect and arrhythmia, which would be caused by “Myocardose” due to abnormal protein.
Chest X-ray findings frequently showed increased bronchial trees and pneumonia, that reflect decreased resistance against infection. In addition, X-ray examination revealed masses from ribs, sternum or other bones in 4 cases. Skull X-ray showed punched-out in 17 cases.
Ten cases had been treated by adrenocortico-steroid hormones that was apparently effective in life extension, as compared with the other 12 cases who did not received steroids and died within 60 days of admission, while the group received steroids lived more than 100 days with tendency of longer life as much as the amount of steroids. At present one case has been living over 700 days.
We experienced 22 cases of multiple myeloma and described their clinical findings.

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The author conceived that an early discovery has great significance not only in congenital dislocation of hip but also in other orthopedic diseases involving congenital torticollis and congenital club foot, and examined all the newborns and immature babies within one week after birth. These babies had been hospitalized to the obstetric and pediatric departments of Matsumoto National Hospital. In the present study, mobility and relaxation of joints, presence of muscular hardening, contracture and click signs were examined at the newborns' room; but an x-ray examination was limited to the cases in which any of the conditions could be clinically suspected of. Besides, in order to prevent a possible oversight during these examinations, all the newborns were instructed to undergo radiography and a check-up at age of 3 months old. Since 1962, 1, 463 cases have been examined up to now. Among them we found 46 cases of congenital torticollis, 16 cases of congenital dislocation of hip and its suspected type, 1 case of birth palsy, 1 case of infantile cerebral paralysis, 1 case of constitutional disease of bone and 22 cases of other anomalies of the face, fingers, feet and toes. All the babies who had not shown any abnormality at the newborns' examinations are now under our investigation. Congenital dislocation of hip has been discovered only 1 case by a radiograph taken at 3 months after the birth. However, congenital displasia of acetabulum was seen in 9 cases, and congenital torticollis in 5 cases, tine case of the constitutional disease of bone was found by the present examinations and still he is under observation up to present at the age of 3 years.
This will provide some precious data in future. From the results of these examinations, the author fully realized the necessity of combining Barlow's test, Ortolani's test and other various methods in the orthopedic examinations of a newborn, and the importance of a sufficient mastery of the technique in these examinations through repeated experiences with an increasing number of cases, for it will certainly enhance the rate of discovery and accomplish the aims of early treatment.

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The sera with positive CRP and low titer of ASLO showed the increase of α₂ globulin and appreciable decrease of albumin in electrophoresis. The sera with negative CRP and high titer of ASLO represented approximately same electrophoretic pattern as positive CRP sera, but there was some significant differences in albumin fractions between sera with positive CRP and high titer of ASLO.
Above mentioned results were discussed from the viewpoints of the functions of serum protein fractions.

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The influence of the fixative on staining with P. T. A. of thin section was studied on the electron microscope. Normal mouse lung, experimental lung tumour by means of 4-Nitroquinoline N-oxide and tuberculous granulomatous tissue in the rabbit lung were carried on this experiment.
P. T. A. has been used as an electron stain in different techniques. Some of its most suitable applications have been the satining of connective tissue fibres and plasma membrane of various types of cells. Floating thin sections were stained with P. T. A. after the bleaching with periodic acid (Marinozzi et al.). By means of P. T. A. staining, an elegant visualization of the elastic tissue in normal mouse lung, experimental lung tumour and others was possible when the samples were fixed in glutaraldehyde only, or were fixed in. glutaraldehyde, postfixed in osmium tetroxide, and then embedded in Epon 812.
Collagen fibres and plasma membranes were stained under these ways. However, when high pH values of P. T. A. solution (higher than pH 1. 9) were employed, their stainability came to decrease. On the contrary, plasma membrane derivatives, i. e. pinocytes and multivesicular bodies, and nucleus and ribonucleic particles came to show the stainability to P. T. A. When the staining was applied to a sample which had been fixed only with osmium tetroxide, the stainability of the elastic tissue was weaker and less specific. Galgi apparatus, membranous components of endoplasmic reticulum and nuclear membranes were never stained with P. T. A. The unit membrane was demonstrable not only on the plasma membranes, but on the pinocytes, multivesicular bodies, endoplasmic reticulum and mitochondria also, all of which are considered to display continuity. However, their membrane components had different stainability to P. T. A.
It is supposed that the stainability to P. T. A. depends upon the molecular structure of the unit membrane in each membranous organella, especially on the various state whichh might change according to the physiological conditions of the cells and the functions of the organella itsself.

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Lymphographic studies have been performed on 67 patients since December, 1963. Approximately two third of patients had carcinoma of the stomach, rectum and breast, malignant lymphoma and swollen limbs. Our lymphographic studies were based on the Kinmonth's method with minor modification.
We reported nine interested patients. They were as follows:
Patient 1: A 61 year old man was hospitalized with carcinoma of the stomach and carcinomatous peritonitis after gastrectomy. Bilateral lower limb lymphographic studies disclosed moth-eaten appearances in the para-aortic lymph nodes and persistence of the contrast material in the cisterna chyli.
Patient 2: A 37 year old man was admitted to our hospital with carcinoma of the rectum. As the radical resection was impossible, an artificial anus was made. Bilateral lower limb lymphographic studies revealed enlargement of both subinguinal superficial, external iliac and common iliac nodes and irregular filling defect of the large right Rosen-Müller's node.
Patient 3: A 46 year old man received resection and anastomosis of the small intestine for cancer of the small intestine. Bilateral lower limb lymphograms showed that abdominoaortic vessels increased in numbers and sizes and reflux of contrast material into the left iliac wing collateral.
Patient 4: A 69 year old female was diagnosed as having carcinoma of the cecum, for which ileocolostomy was performed.
Bilateral lower limb lymphographic studies revealed ghostlike appearances as secondary evidences of metastatic lesions in the right para-aortic area and enlargement of the paraaortic nodes.
Patients 5: A 48 year old female was hospitalized with carcinoma of the left breast. Left upper limb lymphograms showed lateral and central axillar, pectoral, infraclavicular and inferior profundal cervical nodes increased in numbers and sizes.
Patient 6: A 60 year old man had carcinoma of the rectum. His lymphograms showed moth-eaten appearances in the Virchow's lymph nodes.
Patient 7: A 55 year old man was admitted to our hospital with malignant lymphoma of both axillary and supraclavicular area. Bilateral lower limb lymphograms demonstratedd lacy appearances of both large abdomino-aortic, common iliac and external iliac nodes. The tumors were irradiated with use of the tele cobalt unit by way of eight ports. A total of 17050 r in air was given over the tumors for 102 days. The lymphograms disclosed apparently reduced size 3 of tumors. The patient tolerated this therapy well with goodd subjective response.
Patient 8: A 12 year old girl had a one year history of swelling of the left lower limb with unknown cause. The left lower limb lymphograms demonstrated the marked increase in numbers, sizes, tortuousities, collateralizations, dermal backflows of lymphatics in the left lower limb.
Patient 9: A 53 year old female received total removal of the uterus for carcinoma of the uterus. After bilateral lower limb lymphographies, the oil embolism occured in both lungs. Immediate film of the chest showed generalized small punctate densities throughout both lungs, with reticular patterns in the magnified view of the right lateral upper area.
The moth-eaten apperance was only seen in the lymphogram of patient with advanced carcinoma. It was important finding to increase in numbers and sizes of lymph nodes what were impossible to differentiate from inflammatory nodes before becoming filling defects.
In such a case showing a ghost-like appearance, it was very important to compare immediate films with twenty-four-hour films.
Photomicrograph of lymph node with reactive lymphadenitis after injection of contrast material showed many clear spaces in its parenchyma, but photomicrograph of lymph node with carcinomatous metastasis demonstrated almost no clear spaces in the carcinomatous tissues. It seemed that contrast materials were seen as clear spaces. Therefore the carcinomatous lymph tissue area was demonstrated as a f

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Our new simplified technique for the roentgenologic examinations of the colon has undergone improvement better than old method. The following results were the advantages of this new technique:
1. A closed system with avoidance of spillage of barium and feces, and the creation of offensive oders.
2. Good adhesion of wall and fine appearance of relief by zoliation of barium.
3. Evacuation controlled by the examiner.
4. The time of the examination was shortened.
5. More comfortable and reassuring procedured for the patients.
6. Labor saving and improved over-all efficiency.
7. Disposability of the enema apparatus.
8. Sanitary and low cost.
9. Prevention of the enteropathogenetic infections from patient.
10. Esthetically a more satisfactory method of colon examination.

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The material consisted of 229 cases which were found radiologically to have bone metastasis from May of 1962 for 3 years at the National Cancer Center Hospital This report is the study of the radiological changes of the metastatic bone lesion by the various treatments.
1. Bone metastasis primarily occurred to the particular site of the scapula, humerus, femur and of the hip bone.
2. The pictures of the improvement in the metastatic lesion were generally the reappearance of the bone contour and its clear manifestation in the bone cortex, the sclerosis around the osteolytic area and the patchy sclerosis in the spongiosa.
3. The radiological remission rate was 22.2 oa in the osteolytic type, 46.8% in the combined type and 44.4% in the osteoplastic type of bone metastasis. It was higher rate in the cases of the combined type and of the osteoplastic type.

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Authors already reported the radioisotope sceanning of the liver, the spleen, the pancreas and the kidney. These scintigrams are so much helpful for the diagnosis of the abdominal masses.
The differential diagnosis of retroperitoneal tumor from liver swelling, swelling of
the left lobe of liver from splenomegaly and swelling of kidney from splenomegaly are not so easy with only abdominal or chest X-ray pictures, but scintigrams play very important role for the diagnosis. Frequently the superimposition of the scintigram and X-ray picture is greatly useful for the purpose of the diagnostic interpretation.
And these scintigrams indicate the shape and the size of abdominal masses and the extent of invasion of the masses into adjacent organs. Functional and morpholgical changes of adjacent organs are also shown on the scintigrams.

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Three hundred fourteen cases of glomerulonepbritis were admitted to The 2nd Tokyo National Hospital from 1955 to 1964. By the follow up study, clinical courses of 81 cases after the retirement were clarified.
The patients were devided into two groups; group A-the onset was clear after the preceding infection, group B-the onset was obscure without precedingg infection.
In group A, results of the follow up study were as follows: cure 29 cases (50.9%) latent stage 13 cases (22.8%), chronic progressive stage .5 cases (8.8%), renal failure 4 cases (7.0%) death from uremia 2 cases (3.5%), death from another cause 4 cases (7.0%). In the cases of cure, recovery was recognized within 6 months in more than half of cases, and more longer terms were necessary in the other cases. Even in the cases considering to pass into chronic stage by lasting albuminuria for over 6 months, 36% of cases were recovered.
In group B, cure 8 cases (33.8%), latent stage 5 cases (20.8%), chronic progressive stage 0, nephrotic stage 2 cases (8.3%), renal failure 1 case (4.2%), death from uremia 5 cases (20.8%), death from another cause 3 cases (12.5%) were found. The two courses were observed in chronic nephritis; the one stayed in the latent stage for a long time without progress, the other was progressive from the onset, lasted hypertension and microscopic hematuria, and passed into renal failure within a short lapse of time.
The percentage of cure in nephrotic syndrome was only 24%.

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A modified Wilhelmy balance which was commonly used to measure the pulmonary surface activity was made in our laboratory and some basic studies on the operation of this apparatus were performed. Conclusions obtained as follows:
1. DPL and normal lung extract showed low minimal surface tension when area was compressed to 20% of initial area. The tension-area diagrams of them showed fat hysteresis loop. Minimal surface tension of albumin combined DPL was 8.5 dynes/cm ±0.7 lynes/cm.
2. When area was compressed less than 20% of initial area and under 10 cm², the surface tension of albumin combined DPL reached under 10 dynes/cm, and that of normal lung extract under 5 dynes/cm.
3. There was no significant difference between sinusoid drive and triangular drive of barrier moving on maximal and minimal surface tension.
4. It is adequate to operate this apparatus in the following conditions:
1) Area change: between 45 cm2 and 0 cm².
2) Barrier drive: sinusoid or triangular.
3) Time for one cycle: 5 minutes.

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There are some reports that recognized existence of the relationship between Vitamin. B₆ and arteriosclerosis, Also Schroeder and others reported that Vitamin B6 treatment has a cholesterol-lowering power. It is not always said that hypercholesterolemia induced to arteriosclerosis, but we can not denied that there are some relationship between hypercboiesterolemia and arteriosclerosis.
Thus we studied with the cholesterol-lowering effects of pyridoxine HCL (80-150 mg/day orally)
Our results are as follow:
1) In this case cholesterol-lowering effects were seen in about 20-40% and levels of serum cholesterol were reduced to about 80-90% of the former levels. But when the former levels were beyond 300mg/dl, these effects were less.
2) In the cases of arteriosclerosis and obesity some effects (in about 40% cases). were obtained, but in nephrosis, diabetes mellitus, fatty liver and so on no effects were seen.
3) In the cases of combined therapy with pyridoxine and jodlecithin cholestrollowering effects were larger than the effects of only Vitamin B₆.

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Members; National Sanatoriums Yagatabaru, Akasaka, Tobase, Hikarinosono, Kawatana, Toyofukuen, Saishunso, BeppusO, Ginsuien, Chasa, Kirishima, Koseien, Nichinan, Akae, Kikuchi, Fukuokahigashi, Akune and Kagoshima.
The following conclusion has been acquired from 128 tuberculosis cases accompanied by Diabetes Mellitus.
1) Male to female ratio of tuberculosis accompanied by diabetes mellitus is 2.3 to 1. The ratio of the above combination in those loder than forty years old is five times as high as those younger than that.
2) 13.2% had obesity before the discovery of diabetes mellitus. In male, they were normally developed of cachectic and in female they were normally developed or obese.
3) Past history including resection of the stomach, diseases of the central nervous system, glycosuria, use of steroid hormones, endocrinological diseases and delivery of an over developed newborn must not be overlooked.
4) Onset of tuberculosis under 40 years old is not significantly noted in cases out of 14 families with diabetes mellitus.
5) Diabetes mellitus follows tuberculosis in 70.6%, At the time of discovery, 91.2% had moderate to far-advanced tuberculosis (NTA classification), 69.0% had cavity, 38.7% had positive tuberculosis bacilli in sputum. Culture was positive in 53.2% for the bacilli. 55.9% had 1 hour ESR of more than 16.
6) At the time of the discovery, the symptoms and signs were mild; ie, 78.5% had fasting blood sugar of less than 200mg per 100ml. (H. J-Method), 72.8% had 24 hours urinary glucose loss of less than 30Gm. Many of the laboratory studies were within normal limit except for total cholesterol, relatively many of which were abnormal or in higher level of normal limit.
7) At the discovery of diabetes mellitus, a half of the cases had been put on secondary tuberculosis agents, because mild diabetes mellitus had not been treated. This fact shows how important is the discovery and treatment of diabetes mellitus at early stages.
8) Diabetes mellitus was controlled by the fasting blood sugar level at the time of discovery. Higher than 200mg per 100ml, was put on Insulin and D. M, diet. Less than 200mg per 100ml, was put on oral D. M. agents and D. M. diet. Lower than 160mg per 100ml. was controlled just by D. M, diet.
From the above result and the fact that diabetes mellitus and tuberculosis develop in the same age group, investigation must be done even at Sanatorium for diabetes mellitus.
Especially in those older than 40 years old, studies for diabetes mellitus should be energetically performed at least by two hours post prandial blood sugar and urinary glucose examination.

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During the past 7 years 42 out of 2, 603 (1894 males, 709 females) hospitarized pulmonary tuberculous patients had diabetes mellitus. There was no differece in sex distinction. The yearly percentage of this complication was about 1.5% and did not show any remarkable change since 1959 to 1963, but increased to 2.35% and 4.26% in '64 and '65. These patients with both diseases increased between age of 30 to 60 years old, on the other hand the age peak of pulmonary tuberculosis was between age of 50 to 60 ?years old. Therefore we cannot decide that patients with both diseases recently increased following the increase of the old aged pulmonary tuberculous patients.
The numbers of patients suffering from both diseases at the same time (B group) increased markedly in '64 and '65 compaired with that of the previous 5 years, therefore the numbers of B group were equal to that of C group (suffering from pulmonary tuberculosis before the development of diabetes).
Before administration into our sanatorium a majority of A group (suffering from diabetes before pulmonary tuberculosis) had no insulin therapy. In B group a greater parts of patients administered into our hospital soon after the diagnosis of both diseases. In C group a majority of patients diagnosed as diabetes on administrated period and on the screening test of glycosuria 2 hours after breakfast. 28 hospitarized patients suffering from both diseases in '64 and '65 were classified into 20 adult type diabetics and 8 juvenile type diabetics. The rate of juvenile type diabetics in pulmonary tuberculosis were more than that of diabetics without pulmonay tuberculosis.
Fifteen cases had been observed more than a year after classified into two groups, fair controlled and uncontrolled ones, and we compaired their chest roentgenogram and tuberculaus bacilli in sputum. A greater parts of chest roentgenograms in fair controlled group improved moderately, but in uncontrolled group there were no improvement. Tuberculous bacilli in sputum in uncontrolled group also diminished in all cases. Having examined these growing worse cases, we consider that they were aggravated with hypoglycemia due to overdoses of insulin rather than deficient insulin therapy.
Accorping to our preliminary report in July, 1964, 41 out of 476 pulmonary tuberculous patients had positive urine glucose 2 hours after breakfast. 2 years after 46% of 435 patient without glycosuria are still hospitalized and 9.8% of them were dead. The other hand 51.2% of 41 cases with glycosuria are still in hospital and 12 % of them were dead.
Among 12 suspected diabetics 2 cases changed to diabetics 2 years later, 4 cases were suspected diabetics, but did not revealed normal pattern.

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During the period from 1955 through 1966, we had 53 cases of pulmonary tuberculosis accompanied with diabetes in our sanatorium. The percentage of this complication to 5373 hospitalized pulmonary tuberculous patients in this decade is 0.99%. 42 were men, 11 were women. 33 of 53 cases had relatively mild diabetes.
At first, we put together unconditionally the several factors that may have important influence on the result of chemotherapy, and compared the therapeutic effect of pulmonary tuberculosis between the group of patients with diabetes and without diabetes.
As a result, it is suggested that the therapeutic effect of the non-diabetic group is better than that of the diabetic group.
Then we compared the effect in the matched pair of both groups with the same several factors. In this way, there was no appreciable difference of effect in the matched pair and this effect was independent of severity of diabetes.
Of the 53 patients, 16 underwent thoracic surgery. One of these 16 had a complication of bronchial fistula. Other patients did well following surgery.
From this study, it appears justifiable to conclude that the effects of treatment of pulmonary tuberculosis with diabetes who receive adequate therapy should be similiar to that of the non-diabetic tuberculous patients.

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This report is a part of results in joint research carried out at Kyushu National Sanatorium. The apparent diabetes mellitus and the cases presented glycosuria were classified in four groups; A-group: under 110mg % of fasting blood sugar without diabetic therapy, B-group: below 140mg %, C-group: 140mg % to 200mg %, D-group: over 200mg % with diabetic therapy.
1) Cavities were seen radiologically in 70 % except D-group which had higher rate.
2) Improvement rate of tuberculoss lesions were 40% in A-group, 34% in B-group, 11% in C-group and 29% in D-group.
Aggravation rate of lesions were 4% in A-group, 5% in B-group, 11% in C-group and 29% in D-group. Improvement rate of cavities were 35% in A-group, 19% in B-group, 0% in C-group and 17% in D-group. Aggravation rate of cavities were 1% in A-group, 5% in B-group, 10% in C-group and 17% in D-group. Above percentage points out unfavorable progress of pulmonary tuberculosis with diabetes.
3) A.F.B. positive rate was 70% in the cases with cavities, in which only D-group had higher bacilli positive rate, but in the cases without cavity bacilli positive rate were 18% in A-group, 30% in B-group, 71% in C-group and 100% in A-group.
4) Negative conversion rate was 60% in the cases with cavity and 70% without cavity. Only D-group had lowere negative conversion rate.
5) In the cases with high fasting blood sugar level drug resistance appeared at an early stage and showed high rate.
Above results point out that control of diabetes mellitus is necessary for the treatment of tuberculosis, and in the cases which is difficult to control diabetes the device of chemotherapy is important by checking appearance of drug resistant A. F. B.

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Screening test for diabetes was carried out in the tuberculous inpatients in 23 tubercuious sanatoria in Kyushu district, and obtained following results.
The procedure of screening test for diabetes was tested with Tes-tape. The urine sample obtained 2 hours after breakfast was tested for 3 days. Blood sugar was estimated in the 2nd examination only for the patients with positive results 3 times continuously, and judged based on the standard of our group.
Thes screening were 3 times, (i. e. the 1st screening April 1965, the 2nd screening December 1965, the 3rd screening July 1966. ) The Beta in this report presented the result of the 3rd screening. Out of 6065, 15% of male and 7.6% of female (12.7% in average) were positive more than once. And 7.4% of male and 4.4% of female (6.1% in average) were positive 3 times continuously. The diabetic patients totalled 222 (3.7%), including 157 of male (4.1%) and 65 of female (2.9%). These percentages are slightly higher than those of the 1st screening which were 3.1, % in average, but as same as those of the 2nd which were 3.7%.
The newly discovered patients by this screening test were 51.0% in average, including 54.8% of male and 41.6% of female.
It is supposed that the percentage of diabetic patients is considerably high, if undiscovered diabetic patients were added to the patients discovered by the examinations on admission.

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The material consists of 140 patients with AML who were registered from July 1, 1959 to November 30, 1963, Only those who presented themselves without receiving any treatment were included. They were divided into two age groups, i. e., children group (below 15 years) and adults group (15 years or over). One of therapeutic schedules was chosen by opening a sealed envelope containing the schedule to be applied, i. e., the small dosage of Prednisolone 0.5mg/kg/day (Aa) or the large dosage of Prednisolone 2mg/kg, 'day (Ab), in association with an ordinary dosage of 6-MP, i. e., 2-3mg/kg/day. The schedule was continued 4-8 weeks till a remission was acquired or toxic manifestations prevented further administration. Results: In children, remissions were acquired in 52.49 (11/21) in the Aa and in 55.0% (11/20) in the Ab. The total remission rate in children was 53.7% (22/41). In adults, remissions were gained in 28.6% (14/49) of the Aa and in 20.0% (10/50) of the Ab. The total remission rate in adults was 24.3% (24/99), Thus lower rates of remission were noted in large dosage of Prednisolone in adults, but the difference are not statistically significant. The numbers of survived at 8 weeks after start of treatments were compared. In children, the survival rates were 61.9% in the Aa and in 65.0% in the Ab in both dosage groups, while in adults it was 42.8% in the Aa and 34.9% in the Ab. Among steroidhormones, Prednisolone “Takeda” was used in the first half period and Dexamethasone (Orgadrone with Prednisolone equivalent dosage) was used in the second half. No significant differences in the remission rate and survival rate were found between these two drugs.
Conclusion: From our experience of 140 cases of AML, it was concluded that the large lose of Prednisolone or of Dexamethasone should not be administered to all patients without preselection.

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Clinical reports on 140 cases of acute enteritis causd by Vibrio parahaemolyticus are collected in cooperation with many workers in national hospitals for 3 years from 1962 to 1965.
This paper treats of the summarization of them and some related works.
Sex and age of patients: Patients are frequently found in twenties and teenagers, regardless of sex. (Table-1) Outbreaks of patients: They are limited to the hot seasons in the year. (Fig. -1)
Main symptoms: Stomach-ache (86.4%), diarrhea (93.6%), fever (78.6%), vomiting (54.3%) and headache (45.0%) are frequently observed. Bloody stools are recorded in 20.7% of cases, but complaints of tenesmus are rarely reported. (Table -2)
Prognosis: These symptoms are resolutive in three days, and serious conditions are never left after the reconvarescens. (Fig.-2)
Initial diagnosis: 44.4% of cases are made temporary diagnosis of dysentery on acute colitis before bacteriological inf ormations are given. (Table -3)
White blood cells: They increased on the first day, and decreased slightly on the third day of illness. (Fig. -3, Table -4)
Hemoglobin, hematocrit of blood and serum protein: They are all increased on the first day, and decreased on the third day of illness. The rise and fall are prominent in severe cases. (Fig.-4, 5, 6)
Blood pressure: It depressed in some cases on the first day of illness. (Fig. -8)
Beginning of the affection: They have a partiality for nighttime in the day. (Fig. -9)
C. R. P, reaction: Most of cases represent positive C. R. P, reaction in the early stage of the illness. (Fig.-10)
Antigen types of collected strains: They are shown in Table -8.
The labor environment and the contraction of the disease: The physical labor for many hours rises the rate to have the disease. (Table -11)

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