医療
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
25 巻, 11 号
選択された号の論文の14件中1~14を表示しています
  • 松原 稔
    1971 年 25 巻 11 号 p. 797-801
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
    Fluorescence corneal angiography is a modification of fluorescence fundus photography. This procedure is very useful in the analysis of vascularization of the cornea.
    In this report, the author discussed the behavior of blood circulation at limbal and new-formed corneal capillaries examined by fluorescence corneal angiography.
    Serial fluorescence corneal angiographs are chronologically divided into four stages. The first stage or prefilling phase, is the earliest time immediately after injection of dye when the dye has not yet reached capillaries. The dye then reaches capillaries and fill them. This stage is termed the capillary filling phase. The third phase of extravasation is the time when the dye leakage break out from capillaries. Finally, the dye leaking from capillaries diffuse into the surrounding tissue, and fluorescence gradually spread in all direction. This last stage is termed the phase of diffusion.
    Fluorescence corneal angiographs of inflamed limbal capillaries and new formed corneal capillaries showed that intensity of the dye leakage from capillaries in proportion to that of inflammation.
    The neovascularization in active processes can be differentiated unequivocally from the pannus depending on such findings as the arrangement of vessels, the shape of apex of capillary loops, and the mode of dye leakage.
  • 栗村 統, 浜田 金三郎, 松田 健一, 香川 治子, 小林 康記, 香川 和徳, 小林 邦彦, 小林 春秋男, 井原 勝彦, 田中 一彦, ...
    1971 年 25 巻 11 号 p. 802-807
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
    The AFP test is a routine examinations to find the primary liver cancer and we collected about 8, 000 blood samples from about 5, 000 cases visited to our hospital during the past 8 months, There were eleven positive cases among them. In this duration, AFP was detected in 7 of 9 cases with the proved hepatocellular carcinoma, thus the result indicated to be 78% of the positivity rate.
    On the other hand, particularly interesting thing is that AFP occured in 3 out of 17 patients with metastatic liver cancer, indicating the positivity rate is 18%.
    The eleventh case in whom AFP was found, was made a diagnosis to be a chronic hepatitis by initial examination, and AFP was still observed in this patient by the follow-up study.
    All other healthy persons and the patients with liver disease or malignant tumors can be shown to be lack of this protein.
  • 佐藤 昭雄
    1971 年 25 巻 11 号 p. 808-817
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
    Chlorpropamide was given to 3 patients with idiopathic diabetes insipidus, a patient with nephrogenic diabetes insipidus and 8 normal controls. Chlorpropamide decreases, diuresis, increases, the osmolality of urine and decreases the clearance of “free” water which may become negative, without affecting the osmolal clearance.
    A patient with nephrogenic biabetes insipidus showed no depressive effect on urine flow during chlorpropamide administration.
    In 8 normal controls administration of chlorpropamide neither cause any decrease of diuresis, nor modify the osmolality of urine or the clearance of “free” water and did not affect glomerulal filtration rate, urine 17-KS and 17-OHCS excretion.
    During treatment by chlorpropamide on diabetes insipidus administration of sodium chloride in excess (10 gm per day) did not increase the diuresis, and other hypoglycemic drugs such as tolbutamide or biguanide produced no antidiuretic action. In the same patients chlorpropamide was more active than hydrochlorothiazide.
    This treatment could be continued effectively for four years without any decrease of its potency. These results lead to the conclusion that chlorpropamide has antidiuretic action similar that of vasopressin.
  • 島村 喜久治
    1971 年 25 巻 11 号 p. 819
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
  • 久世 彰彦
    1971 年 25 巻 11 号 p. 820-826
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
    This study concerns 364 patients with pulmonary tuberculosis who had been hospitalized in the Hokkaido Dai-ni National Sanatorium in August, 1970.
    Of these patients, 128 were far advanced, belong to N2b, N3a, Nab groups according to the “not easy curable” classification (GAKKEN).
    Eighty per cent of these 128 patients had received various antituberculous drugs over 5 years. The chemotherapy consisted of ethambutol and other drugs were effective for these patients, particularly the regimen of rifampicin and ethambutol showed remarkable effectiveness. The sputum conversion rate was 70 per cent in rifampicin and ethambutol group as compared to a rate of about 40 per cent in ethambutol and other drugs excluding RFP after 6 months of treatment.
    Among 131 patients of Nb group, hypercapnia were seen in 45 cases. The CO2-narcosis cases were more frequent in the patients who had received thoracoplasty. For the treatment of far advanced pulmonary tuberculosis, laboratory data of gas analysis of the blood has very important role.
  • 吾妻 洋
    1971 年 25 巻 11 号 p. 827-832
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
    1) The author studied the present condition of 405 of initially treated cases and 216 of so-called not easily curable pulmonary tuberculous cases (1. resistant to SM and INH, 2. both lungs with over 2cm of definite cavity) who were treated internally.
    2) 0.5% of initially treated cases with chemotherapy failed in bacilli negative (table 1). Therefore, it is important to prevent intractability of most of the not easily curable pulmonary tuberculosis that we experience daily by treating them sufficiently on their initial therapy.
    3) 31% of the intractable cases are still hospitalized and 38% have already died. Only 1 case died after bacilli negativation (table 3).
    4) The conversion rate of the combined therapy with three sensitive drugs, two sensitive drugs, one sensitive drug and only resistant drugs were 62.5%, 35.1%, 7%, and 2.5% respectively (fig. 3).
    Even if the background factor is the same, this relation shows same conclusion. The effects of EB., TH., and RAMP are outstanding (table 4, fig. 8).5) The most important factor concerning bacilli negativation is the apphication of number of combined sensitive drugs but the diameter of largest cavity (fig. 4), total cavity diameter (fig. 5), NTA, extension of foci (fig. 6) and age (fig. 7) seem to be not so important factors.
    6) The principle of the internal therapy of not easily curable pulmonary tuberculosis is the same as the principle of chemotherapy; that is, the combined therapy of sensitive drugs is important, therefore it is desirable to use the combination of the strongest drugs as much as possible. Not only it is difficult to obtain enough result by supplementing dne sensitive drug to the ineffective drugs now used but also there is a fear of making this drug resistant.
  • 豊原 弘
    1971 年 25 巻 11 号 p. 833-843
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
    In the recent 3 years from July 1967 to September 1970, 160 cases of severe pulmonary tuberculosis were 6analyzed on the result of treatment and prognosis for finding out more adequate chemotherapy.
    (1) The anti-tuberculous drugs were evaluated as follows; they were A class (INH, EB, TH, RFP, SM, KM, CPM), B class (PAS, CS, VM, PZA) and C class (SF, TBI). The rate of negative conversion of tubercle bacilli in sputum was higher in the combinations of three drugs in A class or two drugs in A and one in B (60%) than in the other combinations. Two drugs in A and one in C showed 40%. One drug in A and in C showed 25%.
    (2) The improvement of X-ray findings was shown in 46% and the passing exacerbation was in 8% of 70 cases of the group of negative conversion of tubercle bacilli. In contrast, 52% in 90 cases of the positive bacilli group showed the exacerbation and only 11 ib showed the improvement in X-ray film. At the time of the exacerbation, drugs were used in weak combinations.
    (3) 108 cases showed less than 50% of VC. PaO2 and PaCO2 were analyzed in 70 cases of them. Hypoxemia occured in 23 cases of the group of 50-41% of VC (29 cases) and in all of the group less than 40% of VC (41 cases). Hypercapnia was shown in 13 cases of the group less than 40% of VC.
    (4) 39 cases died of causes as follows; pulmonary failure, hemoptysis, non-tuberculous disease and suicide. 46% of these cases involved pulmonary failure.
    These findings suggest that the best result obtained when severe pulmonary tuberculosis is treated with the unused sensitive three drugs of A class. When bacilli are ont converted to negative after 3-4 months, all drugs should be changed to three or four other sensitive drugs at once. Furthermore, the lower respiratory function should be carefully controled.
  • 笹部 哲哉, 森本 一良, 川田 嘉二, 江口 享
    1971 年 25 巻 11 号 p. 845-848
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
    A 37-year-old woman with a history of lumbar spine tuberculosis at the age of 7, developed a compression myelopathy, for which a laminectomy was performed. Two and half months later, she complained of disturbance of lateral gaze of the right eye-ball and numbness of the right side of the face. Neurological examination revealed types of infranuclear lesion of the right trigeminal nerve, nuclear or infranuclear lesions of the right abducens and hypoglossal nerves. Homer's sign was observed at the right side. Motor, sensory, and reflex systems in both upper extremities were normal. Both lower extremities showed lower motor neuron lesion. On the other hand, chest films, cerebral angiograms, pneumoencephalograms (fractional) were all negative. Autopsy disclosed that primary lung adenocarcinomas metastasized to the posterior wall of the thoracic cavity, liver, retroperitoneum, lumbar spine and intracranial basal part. The metastatic basal tumor extended from the middle to the posterior cranial fossa. This case has been described in this report.
  • 河合 恒雄, 井田 時雄, 永岡 貞男
    1971 年 25 巻 11 号 p. 849-856
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
    An autopsy case with right testicular mixed tumor of immature teratoma in a 28-year-old man was reported.
    He was poor in prognosis because of delaying of his early consultation.
    He was referred to our hospital after the development of metastasis on retroperitoneal and supraclavicular lymph nodes and died 10 months later.
    Autopsy revealed metastasis of the paraaortic, left iliac and supraclavicular lymph nodes and, moreover, lung, liver and peritoneum.
    Microscopic study revealed mixed tumor with embryonal carcinoma, immature and mature teratoma which corresponded with group IV in the classification of Dixon and Moore.
    Serum lactate dehydrogenase levels were in parallel with vicissitude of the tumor and finally arose to 1990 units.
    The literature was reviewed, and diagnosis and treatment were discussed.
    Testicular tumor is extremely rare, but very important in the fact that it has become curable by the recent advanced techniques of diagnosis and treatment. The treatment mainly consists of high orchiectomy and irradiation. Linear accelerator x-ray therapy is the best method of radiation therapy for testicular tumor.
    Emphasis was placed on the importance of early detection and appropriate early treatment in testicular tumor.
  • 石井 奏, 安間 力, 斉藤 輝夫
    1971 年 25 巻 11 号 p. 857-860
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
    Pentazocine (Sosegon), a new non-narcotic analgesic was used for premedication on 63 patients, The following results were obtained.
    1) The drug was an effective sedative given before anesthesia.
    2) No side effects on the respiratory and circulatory system were observed in this clinical study.
    3) In some instances slight nausea and dizziness occurred, but no treatment was required.
    It was concluded that pentazocine is an effective pre-anesthetic drug.
  • 岡本 進, 田村 潤
    1971 年 25 巻 11 号 p. 862-863
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
  • 7. 千葉大学採血ミス事件第一審判決
    寺畑 喜朔
    1971 年 25 巻 11 号 p. 865-866
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
  • 1971 年 25 巻 11 号 p. 867-869
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
  • 1971 年 25 巻 11 号 p. 869-871
    発行日: 1971/11/20
    公開日: 2011/10/19
    ジャーナル フリー
feedback
Top