Dental Journal of Iwate Medical University
Online ISSN : 2424-1822
Print ISSN : 0385-1311
ISSN-L : 0385-1311
Search
Advanced search
OR
Browse
Search
Volume 39, Issue 1
Displaying 1-7 of 7 articles from this issue
Show all abstracts
    • |<
    • <
    • 1
    • >
    • >|
Originals
  • Effect of mandibular displacement on brain activity
    — A Functional Magnetic Resonance Imaging Study —
    Hiroyuki Sakuraba, Takuya Kobayashi
    Article type: Article
    2014 Volume 39 Issue 1 Pages 1-13
    Published: April 23, 2014
    Released on J-STAGE: March 05, 2017
    DOIhttps://doi.org/10.20663/iwateshigakukaishi.39.1_1
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    It is reported that mandibular displacement causes various problems. However, mechanisms of those relationships haven't been revealed. In order to reveal the influence of mandibular displacement on brain activity, we examined brain activity using fMRI during tapping and clenching movements. Ten healthy subjects performed tapping and clenching in an intercuspal position (Control) and in horizontal mandibular displacement conditions (Front, Left, Right). The entromedial prefrontal cortex (VMPFC) and amygdala were not activated in control condition during tapping and clenching. The amygdala was activated during tapping with horizontal mandibular displacements. The extent of activation in the amygdala during tapping with the horizontal mandibular displacements was significantly higher than those in the control group. During clenching, the VMPFC and amygdala were activated in horizontal mandibular displacement conditions and the extents of activation were significantly higher in the horizontal mandibular displacements than those in control condition. Those results suggest that horizontal mandibular displacements may cause discomfort and pain regardless of direction and kinds of movement. Those results suggest that the clenching accompanied with severe mandibular displacement or malocclusion could cause stronger stress responses.
    View full abstract
    Download PDF (19873K)
  • Localization of the red fluorescence and characteristics of culture cells derived from salivary gland of tdTomato mice
    Shinji Furukawa, Kazuro Satoh, Akira Fujimura, Masato Ohtsuka, Hiroyuk ...
    Article type: Article
    2014 Volume 39 Issue 1 Pages 14-28
    Published: April 23, 2014
    Released on J-STAGE: March 05, 2017
    DOIhttps://doi.org/10.20663/iwateshigakukaishi.39.1_14
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    The red fluorescent transgenic (tdTomato) mice are considered to be of great value in studies of regenerative medicine. One of their noteworthy features is that cultured cells from these mice show extremely strong red fluorescence, enabling real time observation of the cells examined through the body surface of grafted animals. This study will focus on the cellular distribution of red fluorescence in the submandibular and sublingual glands of tdTomato mice, the status of red fluorescence expression, the cell migration, and the stem cell marker gene expression of cultured cells from each salivary gland. Red fluorescence expression was observed in submandibular and sublingual glands. Interestingly, the intracellular localizations of red fluorescence coincided with those of F-actin. In addition, a difference in the intracellular red fluorescent distributions between the cells derived from each salivary gland was observed. We also found that the cells of submandibular gland origin showed significantly higher migratory activity than those of sublingual gland origin. Finally, we established that the mesenchymal stem cell marker positive cell line derived from the submandibular gland. Established cell lines could be useful for kinetic studies of mesenchymal stem cells in vitro and in vivo.
    View full abstract
    Download PDF (29374K)
Case reports
  • A Case of Rocuronium-induced Anaphylactic Shock during Induction of General Anesthesia
    Yutaka Shinohe, Hitoshi Miura, Nozomu Sakamoto, Masahito Sato, Tomohir ...
    Article type: Article
    2014 Volume 39 Issue 1 Pages 29-36
    Published: April 23, 2014
    Released on J-STAGE: March 05, 2017
    DOIhttps://doi.org/10.20663/iwateshigakukaishi.39.1_29
    JOURNAL FREE ACCESS
    Show abstractHide abstract
    We reported that anaphylactic shock was caused by administering intravenously rocuronium during general anesthesia. A 42-year-old female (height 156 cm, weight 48kg) patient, diagnosed with a jaw deformity, was scheduled for the sagittal splitting method of the mandibular ramus under general anesthesia. She was diagnosed with asymptomatic primary biliary cirrhosis at 38 years old and took ursodeoxycholic acid medicine orally. Anesthesia was induced with intravenous fentanyl 50μg, propofol 100mg, remifentanyl 0.1γ c.i.v. and rocuronium 40 mg and maintained with Air, O_2 and sevoflurane. About 10 min after tracheal intubation, the patient developed a skin rash, hypotension (56/30 mmHg) and sinus bradycardia (50 bpm) and was treated with successive administration of adrenaline 0.3 mg i.m., hydrocortisone sodium succinate 500mg, polaramin 5 mg i.v. and was given infusion rapidly from two places of peripheral intravenous lines in accordance with the anaphylactic guidelines. Fortunately, the patient recovered without serious symptoms. The subsequent skin test results led to a diagnosis of rocuronium-induced anaphylaxis. Anaphylaxis is a systemic allergic reaction. Therefore, it is important for not only to begin treatment at the time of onset but also to diagnose serologically and identify the responsible agent with skin testing. When anaphylaxis happens, we must act quickly according to in-hospital guidelines so that symptoms do not make it serious. Moreover, we must fix the cooperation system between medical doctors and nurse.
    View full abstract
    Download PDF (6287K)
    • |<
    • <
    • 1
    • >
    • >|
feedback
 Top