Tests on 3 different tires were performed to investigate the effect of tire pressure on tire rolling resistance and fuel economy in mode running. The test results revealed that the effect of tire pressure on tire rolling resistance is from -16%/50kPa to -23%/50kPa. Next, we simulated fuel economy using the test data for 3 cases for each tire: base pressure, a decrease of 50kPa, and an increase of 50kPa. Compared to the case of a standard tire at base pressure, a decrease of 50kPa resulted in up to 12% worse fuel economy. An increase of 50kPa resulted in a maximum 2% improvement.