The purpose of this multi-institutional study was to investigate the actual condition of five-year survivors in non-small cell lung cancer patients treated by radiation therapy without resection. The final registration time was October 31, 1993. A total of 436 patients from 78 institutions in Japan were registered. An analysis of the characteristics of patients and tumors, treatment planning, tumor response. late radiation injuries, double primary cancer, and other factors was performed.
Two cases of primary malignant lymphoma of the uterine cervix are reported. Both of them presented with vaginal bleeding. One patient had malignant lymphoma of the diffuse small cleaved cell type, and the other lymphoblastic type lymphoma. The stage in both was IIB (FIGO). The former patient, who was treated by radiation therapy, is free of disease and alive and well 4 years after completion of treatment. The patient with lymphoblastic lymphoma received chemotherapy, radical surgery and postoperative radiotherapy, but died of distant metastasis 3 years after initial chemotherapy. Radiation therapy alone is a curative treatment for this rare malignant lymphoma when confined to the pelvis; but for aggressive or extensive malignant lymphomas, combination chemotherapy should be used.