Most of the anesthetic accidents occur during the induction and intubation of anesthesia while the circulatory status is still unstable. We studied on the arterial pressure changes obtained by electric manometer, blood gas analysis by Van-Slyke method, and pre-operative examinations of autonomic nervous system function.
Under normal condition, hemodynamic changes during this period occur through the reflex of sympathetic nerve though vagovagal reflex also exist. The reflex which occurs at laryngoscopy originates from the deep part of the tongue.
The study on various types of induction and the results of blood gases analysis indicates that if S
ao2 and C
co2 remain in normal range the changes are provoked by sympathetic nervous reflex. The changes, however, are intensified if hyperacanea occurs during the period, and in hypoxia parasympathetic nervous reflex is dominant.
It is hard to find the close relationship between hemodynamic changes and pre-operative autonomic nerve function tests.
The most prominent factor influences the hemodynamic changes during induction and intubation is the kind of anesthetic agents and the method of their induction.
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