巻号一覧
14 巻 (1963)
- 6 号 p. 269-
- 5 号 p. 219-
- 4 号 p. 181-
- 3 号 p. 115-
- 2 号 p. 65-
- 1 号 p. 3-
14 巻, 3 号
選択された号の論文の7件中1～7を表示しています
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梶川 欽一郎1963 年 14 巻 3 号 p. 115-125,en1
発行日: 1963年
公開日: 2010/10/20
ジャーナル フリーThe fine structure of fibroblasts in thin sections was studied with the electron microscope in an attempt to determine the site of collagen synthesis and the mechanism of extrusion of collagen precursors. Use was made of the skin of embryonic, newborn and adult mice, and the granulation tissue in the healing of skin wound of mice. Actively functioning fibroblasts were characterized by a well developed endoplasmic reticulum, enlarged Gologi complex and swollen mitochondria. Some filamentous dense materials, presumably collagen precursors, were found within the cisternae of the endoplasmic reticulum and in the peripheral region of the cytoplasm. The newly formed collagen fibrils were found in contact with the cell surface. They developed into mature form in the extracellular spaces. This study emphasized that collagen precursors are produced in close association with the endoplasmic reticulum and sythesized products are accumulated within distended cisternae of of the reticulum and discharged from the cell by perforating the cell surface or through separation of the whole cisternae from the cytoplasm.
Effect of various substances upon the reconstitution of fibrils in vitro from dissolved collagen was also studied with the electron microscope. The results support the view that polymerization of collagen precursors, extruded from the cells may occur through a physicochemical effect of extracellular fluids, possibly with the aid of mucopolysaccharides in the grown substance.
The structural changes of the fibroblasts were observed in some pathological conditions, including human laryngeal nodules, wound healing in scorbutic guinea-pigs and in mice injected with cortisone. The fibroblasts in the laryngeal nodules showed a failure of the development of the endoplasmic reticulum and abundant cytoplasmic filaments, possibly collagen precursors accumulated in the cell matrix instead of within the lumen of the endoplasmic reticulum associated with less abundant RNP particles on the outer surface. Cortisone injection resulted in a striking depression of the proliferation of the fibroblasts, which contained a poorly developed endoplasmic reticulum and many inclusion bodies in the cytoplasm. The possible mechanism of the disturbance of collagen production in these pathological conditions was discussed in the light of the knowledge of fibrogenesis in connective tissue.抄録全体を表示PDF形式でダウンロード (5444K) -
向野 興雄1963 年 14 巻 3 号 p. 126-131,en1
発行日: 1963年
公開日: 2010/10/20
ジャーナル フリーPatients of the cancer of the cervical esophagus that underwent surgical treatment during the past 10 years at the otolaryngological clinic of Kyushu University numbered 28. Of these 13 cases underwent the primary esophageal reconstruction, and 8 cases underwent the secondary reconstruction. In the primary reconstruction the author used the larynx as an autograft to reconstruct the cervical esophagus.
In the secondary reconstrution the author devised a new method combining the use of the skin flap of the neck and of the tube pedicle graft of the chest. The procedure is as follows: first a tube pedicle graft is made on the hairless portion of the left anterior part of the chest, and after a time the left end of the tube pedicle graft is transplanted to the left part of the neck. The inferior part of the cervical esophagus is reconstructed using the skin flap of the neck after U-shaped incision around the esophageal stoma. The end of the tube pedicle graft at the side of the chest is transplanted on to the surface of the wound. Finally, after healing of the wound, the remaining superior part of the cervical esophagus is reconstructed using the skin flap of the neck after inverted U-shaped incision around the pharyngostoma. The surface of the wound is covered with the tube pedicle graft separated again at the suture.
This new method has several advantages. The suture lines of the new esophagus and of the outer part of the neck do not pile at the same position, and fistulization is rare because of the lack of strain. It is not necessary to make a thick tube pedicle graft. The new esophageal lumen is spacious and causes no cicatricial stenosis.抄録全体を表示PDF形式でダウンロード (4469K) -
岩田 逸夫1963 年 14 巻 3 号 p. 133-136,en2
発行日: 1963年
公開日: 2010/10/20
ジャーナル フリーWhen one feels neurotic, autonomic reflex or endocrinological abnormal symptom on the laryngeal region by emotional stress, we define it as laryngeal Psychosomatic disease.
I discussed about the cases of Pharyngolaryngeal neurosis, hysteric hoarse voice, difficult breathing and esophageal spasm from the point of view of psychosomatic medicine.
The medical treatment is principally given by the aid of Psychlogical-treatment, and accessorily by the aid of Drug-treatment.抄録全体を表示PDF形式でダウンロード (1159K) -
日根 其二, 浦上 晋, 関根 惟和, 桑江 良樹1963 年 14 巻 3 号 p. 136-139,en2
発行日: 1963年
公開日: 2010/10/20
ジャーナル フリーBy using Biplane Fluoroscope, the authors have recently succeeded in removing a“Machi-”pin from the bronchiole deep in right inferior lobe of 11-year old boy who swallowed it by accident. As this case can not be done by the traditional photopic vision method, it should be very valuable to make a report on details of Biplane Fluoroscopy with some relating aspects.
The authors are of the same idea with the earlier workers in that this method makes the two dimensional observation possible and can be adequately applied for removing the deep bronchial foreign bodies in X-Ray contrastgraphy. The precautions with special regards to the preventive measures against X-Ray exposure disturbances in applying the method are are also discussed.抄録全体を表示PDF形式でダウンロード (2549K) -
本庶 正一, 関谷 透, 山田 隆志1963 年 14 巻 3 号 p. 140-143,en2
発行日: 1963年
公開日: 2010/10/20
ジャーナル フリー精神異常者の31才の家婦が, 自殺目的で縫針を嚥下した所, 食道外異物となり, 約2週間後喉頭周囲膿瘍を形成した。
頸部外切開により甲状軟骨, 輪状軟骨左側位の膿瘍腔より, 縫針異物を除去, 治癒せしめ得た。抄録全体を表示PDF形式でダウンロード (3500K) -
中川 巌1963 年 14 巻 3 号 p. 144-148,en3
発行日: 1963年
公開日: 2010/10/20
ジャーナル フリーPsychosomatic stabilizor, INSIDON, was given by mouth to patients who had pharyngolaryngeal neurosis.
Those who had organic disease were excluded. The results were compared with the placebo group.
No definite advantages were observed in this drug compared to others.抄録全体を表示PDF形式でダウンロード (1357K) -
高山 乙彦, 菊池 恭三, 石山 英一1963 年 14 巻 3 号 p. 149-153,en3
発行日: 1963年
公開日: 2010/10/20
ジャーナル フリーThe author conducted experiments to investigate the narcotic influence on bronchoesophagical examinations and tonsillectomies using 8% xylocain solution spray.
The results obtained were as follows:
1) The narcotic effects were very excellent and quick.
2) No clear complication was found.
3) The data obtained with 8 % xylocain solution spray were better than the data with 4% xylocain solution.抄録全体を表示PDF形式でダウンロード (1241K)
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