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Volume 23, Issue 1
Displaying 1-8 of 8 articles from this issue
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Symposium: Viral Infection in the AirwayT. Hagihara1972 Volume 23 Issue 1 Pages 1-2
Published: February 10, 1972
Released on J-STAGE: October 20, 2010
JOURNAL FREE ACCESSWith all the recent advancements in virology, there still remain a plenty of unanswered clinical problems in relation to viral diseases. This is particularly so with viral infections in the airway. So in this symposium, I hope to invite active discussions on the basic as well as clinical problems associated with these viral infections from viewpoints of internal medicine, pediatrics, and otorhinolaryngology, and reports on the latest findings as to the diagnosis, treatment, and prevention of the diseases so that our efforts may contribute to rousing the special attention to this problem.View full abstractDownload PDF (214K) -
Isao Ebisawa1972 Volume 23 Issue 1 Pages 3-8
Published: February 10, 1972
Released on J-STAGE: October 20, 2010
JOURNAL FREE ACCESSNasal epithelial cells of influenza patients stained with fluorescent antibody show following features. The localization of antigen is intranuclear, both intranuclear and intracytoplasmic, or intracytoplasmic according to the stage of cellular infection with influenza virus. The ciliated border of the cylindrical epithelial cell fluoresced very strongly throughout the second and the third stages of cellular infection. In addition to this, basal, intermediate, and mucus cells appeared to be infected by the influenza virus. The distribution of infected epithelial cells was not homogenous or diffuse, but isolated cells were infected in some areas, However, continuous cells were also infected in other areas.View full abstractDownload PDF (5015K) -
Ryochi Fujii1972 Volume 23 Issue 1 Pages 9-13
Published: February 10, 1972
Released on J-STAGE: October 20, 2010
JOURNAL FREE ACCESSThe characteristics of ARI in the pediatric age are discussed. The first feature is in its multiplicity of viral etiology and the second one is in its mode of infection particularly among the young infants. Primary infection per se results particular manifestation of clinical signs basedg on the physioanatomical specialities of young infants, which is comprised in the third feature.
382 cases of ARI of known viral etiology which were treated by us in these seven years were analized according to viral origin, signs and symptoms, and age.
It was disclosed that almost all kinds of respiratory virus were prevalent in the Tokyo area with minor difference of clinical manifestation. And children less than 3 years of age have higher incidence of lower respiratory infection than grown-up-children do.
With respect to its treatment, considering the paucity of effective antiviral drugs and effective vaccines except a influenzal one the clinical importance of bacterial secondary infections was stressed.View full abstractDownload PDF (945K) -
Hideo Ishii1972 Volume 23 Issue 1 Pages 14-18
Published: February 10, 1972
Released on J-STAGE: October 20, 2010
JOURNAL FREE ACCESSIn the beginning of the year 1970 we had an epidemic occurrence of recurrent laryngeal nerve paralysis in almost all regions of Japan.
Sixty patients, who have visited the ENT Clinic of our University with paralysis of the larynx, were as follows: male; 33, female; 27, unilateral left side paralysis; 26, unilateral right side paralysis; 13, bilateral paralysis; 21, associated paralysis; 8.
The age of the youngest patient was 20.
Historical examinations revealed that vocal cord paralysis had occurred to the majority of the patients immediately or a little while after an influenzal illness. Complementfixation rection to influenza A was examined with 44 cases, and the reaction was positive on 29 cases, negative on 6 cases, doubtful on 3 cases and the result of the reaction on 6 cases could not be confirmed. Besides complement-fixation tests were tried to 8 kinds of vires; influenza B, PPLO, psittacosis, herpes simplex, varicella, coxackie B-1, mumps and adenovirus. To herpes simplex virus, some cases which showed a little higher titer were recognized.
Laryngeal examinations showed various kinds of paralytical findings of the larynx. The frequent occurrence of bilateral vocal cord paralysis was also a characteristic point of this epidemie.
The patients were treated medicinally. Noticeable effect was obtained very often with the administration of adrenocortical hormone. On some cases of long protracted paralysis stellate block was performed with favorable effect. Our sixty cases were observed for more than one year and showed following results: complete cure on thirty-six patients, favorable on twelve patients, poor on five patients and on six cases the result of the treatment could not be ascertained.View full abstractDownload PDF (964K) -
Masahito Okayasu1972 Volume 23 Issue 1 Pages 19-25
Published: February 10, 1972
Released on J-STAGE: October 20, 2010
JOURNAL FREE ACCESSThere are many complications of viral respiratory diseases. However, I think that the most common and serious illness as complication is influenza pneumonia. My associates and I performed clinical and experimental investigations, and reported pathological views, treatment and prevention of influenza pneumonia and relationship of existing deseases to the pneumonia. When a patient sufferes from influenza pneumonia, we have to pay attention to his liver disorders seriouly in his past history. If a patient had pulmonary tuberculosis, it is necessary to check his low pulmonary function. In cases of chronic obstructive pulmonary diseases, it must be necessary consider on control of respiration in both patterns of restructive disorders due to pneumonia and of obstructive disorders.View full abstractDownload PDF (1074K) -
Masaro Kaji1972 Volume 23 Issue 1 Pages 26-28
Published: February 10, 1972
Released on J-STAGE: October 20, 2010
JOURNAL FREE ACCESSIn spite of many difficulties in the development of antiviral agents, progress has been made both in laboratory works and clinical studies. In the field of viral respiratory infections, N1, N1-anhydrobis- (β-hydroxyethyl) biguanide HCl (ABOB) and amantadine are now available.
The effect of ABOB in the treatment of influenza (A2 and B) and pharyngoconjunctival fever (caused by adenovirus type 3) was shown by shorter duration of fever in treated group than in the control by double blind method. Amantadine was also revealed to be effective for influenza (A2 and Hongkong) in double blind test. Some data were shown in regard to these antiviral agents.
Possibilities of clinical administration of interferon and interferon inducers were also discussed.View full abstractDownload PDF (515K) -
Multiformity of the Laryngeal FindingsSuenosuke Ishii1972 Volume 23 Issue 1 Pages 29-35
Published: February 10, 1972
Released on J-STAGE: October 20, 2010
JOURNAL FREE ACCESSIn 30 children, with hoarseness aged from 3 years to 16 years, the larynx was examined by means of fiberscope and a few remarks were obtained.
In contrast with a contemporary concept in which the most common cause of hoarseness in children is vocal nodules, multiformity of the laryngeal findings in hoarse children was confirmed.
The laryngeal findings were classified into five types.
Type I Red swollen type (chronic laryngitis type) 36.7%
Type II Edematous swollen type 23.3%
Type III Unilateral nodule type 10.0%
Type IV Bilateral nodules type 23.3%
Type V Motor disturbance type (paralytic type) 6.7%
The author believed that the type I was not frequently found in the past but it has been increasing recently in connection with air pollution. In the type unilateral nodule was not uncommon in children and the shape of nodules was variant. The type showedparalytic form without inflammatory change, but the other types were frequently accompanied by so-called recurrent nerve paralysis, lateral muscle paralysis, inner muscle paralysis, insufficient closure of the glottis.
Many of hoarse children have the unbeliebably high incidence (73.3%) of paranasal sinusitis of a moderate or extensive degree. This fact reminded us the importance of paranasal sinusitis which contributed as an etiologic factor to occurrence of hoarseness in children, and the author stressed that a concept of sinolaryngitis should be brought in the further study on hoarseness in children.View full abstractDownload PDF (2762K) -
M. Endo, [in Japanese], [in Japanese], [in Japanese], [in Japanese], [ ...1972 Volume 23 Issue 1 Pages 36-41
Published: February 10, 1972
Released on J-STAGE: October 20, 2010
JOURNAL FREE ACCESSIt is useful to use the detector combined with the esophageal fiberscope. Under direct vision it is possible to find small lesions for the diagnosis of the esophageal cancer. 247 cases were examined by both methods, pull-through and under direct vision. 2% of the cases of cancer except the irradiated cases were diagnosed as non-cancer in under direct vision method. But no benigne cases were diagnosed as the malignancy. In case of the preoperative irradiation 2000rad in dosis, the tendency of the decrease of 32p up-take ratio was noticed. In casesof radical irradiation, the cases which showed low ratio were other the improved cases by X-ray and endoscopical examination.View full abstractDownload PDF (3107K)
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