日本気管食道科学会会報
Online ISSN : 1880-6848
Print ISSN : 0029-0645
ISSN-L : 0029-0645
28 巻, 4 号
選択された号の論文の8件中1~8を表示しています
  • とくに気管支喘息を中心としたProstaglandinsと2, 3の関連因子の検討
    大石 光雄
    1977 年 28 巻 4 号 p. 225-236
    発行日: 1977/08/10
    公開日: 2010/10/20
    ジャーナル フリー
    The plasma prostaglandins (PGE, PGF) and PGF major urinary metadolite (PGF-MUM) levels, 105 cases with bronchial astma, 32 cases with various broncho-pulmonary diseases and 30 cases with normal individuals were mesured using radioimmunoassay method. Various relating factors to PGs and bronchial asthma were also investigated.
    The following results were obtained:
    1. Plasma PGE levels were higher than PGF levels in normal inividuals. PGF-MUM levels at night were higher than that in the day time in normal individuals.(P<0.02).
    2. Urine volume per three hours was correlated with PGF-MUM levels per 1 ml of this urine (r=-0.62, P<0.001), and PGF-MUM levels at night were higher than that in the day time in normal individuals (P<0.02).
    3. Plasma PGF levels (P<0.01), PGF/E raito (P<0.01) and PGF-MUM levels (P<0.001) in the patients with asthmatic attack were higher than those in the attack free individuals, pulmonary tubercurosis and normal controls, but there were no significant correlationship among the patients with lung cancer, bronchiektasis and pulmonary fibrosis. PGF2a-MUM levels in the status asthmaticus were increased significantly.
    4. Plasma PGF levels were correlated with PGF-MUM levels in the patients with bronchial asthma (r=0.67, P<0.001).
    5. The change of PGF-MUM levels in atopic asthma were severe than in non atopic asthma, however, specific relation could not be found between the PGs levels and other factors such as eosinophilus, basophilus, serum IgE levels and type of asthma.
  • とくに気管支喘息を中心としたHLA抗原と2.3の関連因子との検討
    遠藤 文子
    1977 年 28 巻 4 号 p. 237-247
    発行日: 1977/08/10
    公開日: 2010/10/20
    ジャーナル フリー
    Phenotype frequencies and haplotype of HLA antigens in 297 cases with various bronchopulmonary diseases were studied using the method of lymphocyte microcytotoxicity test. The following results were obtained.
    1. High frequencies of HLA-A2, HLA-A9, HLA-B5, HLA-BW40 were recognized in normal individuals.
    2. HLA-BW21 in the patients with chronic bronchitis was higher than those in normal individuals (P<0.05). However, there were no differences of frequencies of HLA antigens in chronic pulmonary emphysema, pulmonary tuberculosis, lung cancer, pulmonary sarcoidosis, cystic fibrosis, bronchiectasis, pneumoconiosis, pulmonary alveolar microlithiasis and normal individuals.
    3. Frequencies of HLA-BW38 in the patient with nasal allergy and frequencies of HLA-BW40 in the patient with bronchial asthma were higher than those in normal individuals (P<0.05). In those various factors, high serum IgE levels and high IgE antibody titers showed to be corelated to HLA-BW40.
    4. We can not prove asscciated haplotype in atopic families. The other hand, relationship between haplotype HLA-A10, B12 and onset of the disease were suggestted in family study of the patient with hypersensitivity pneumonitis.
    5. High phenotype frequencies of HLA-B5 were recognized in acute myelocyte leukemia (P<0.05). HLA-B27 was detected in all patients of ankylosing spondylitis.
  • 瀧野 賢一, 大西 俊郎, 大戸 武久, 多田 寛
    1977 年 28 巻 4 号 p. 248-253
    発行日: 1977/08/10
    公開日: 2010/10/20
    ジャーナル フリー
    Three cases of pneumonia and two cases of pulmonry abscess that were treated by local aspiration of purulent accumulation under bronchoscopy are reported.
    Although it has generally been regarded that bronchoscopic examination is not adequate in cases with pneumonia, the authors demonstrated that local aspiration of purulent accumulation in the lungs by means of a fine, vinyl tubing under bronchoscopy, as a method of active treatment of pneumonia or pulmonary abscess, was beneficial in improving the course of the diseases.
    The authors encourage the wide use of bronchoscopic procedures in cases, with pulmonary diseases including pneumonia as they are very efficacious in the treatment of pneumonia as in differential diagnosis of lung diseases.
  • 石原 恒夫, 菊地 敬一, 井上 宏司, 深井 志摩夫, 小川 純一, 高浪 巌, 武士 昭彦, 古泉 桂四郎, 柳内 登, 奥井 津二
    1977 年 28 巻 4 号 p. 254-258
    発行日: 1977/08/10
    公開日: 2010/10/20
    ジャーナル フリー
    We have treated surgically 20 patients with malignant tracheal tumors for the past 14 years.
    In 11 of the 20 patients, thyroid cancer had infiltrated into the tracheal wall. Ten of the 11 patients had the damages of the cervical trachea. In the remaining one patient, thyroid cancer which had occurred in the mediastinum infiltrated into the lower trachea and the right main bronchus.
    In 4 patients with lung cancer, cancer which had in the right upper lobe bronchus infiltrated into the lower trachea through the right main bronchus.
    There were 2 patients with adenoid cystic carcinoma and one patient with leiomyosa rcoma.
    The remaining 2 patients consisted cf a patient in whom the parathyroid cancer had infiltrated into the cervical trachea, and a patient in whom the lymph nodes with metastasis of the esophageal cancer had involved the large part of the trachea.
    Five of the 20 patients died. A patient with thyroid cancer in the mediastinum died 7 days after the operation because the suturing was inadequate. A patient with lung cancer died of sudden hemoptysis 24 days after the operation. A patient with thyroid cancer extended from the trachea to the right subclavian artery and the right common carotid artery died of bleeding 4 months after the first operation. A patient with adenoid cystic carcinoma died of a metastatic tumor of the lung 5 years and 4 months after the operation. A patient with esophageal cancer died of general weakness.
  • 島田 哲男, 金子 敏郎, 北村 武
    1977 年 28 巻 4 号 p. 259-262
    発行日: 1977/08/10
    公開日: 2010/10/20
    ジャーナル フリー
    2 year baby with congenital chondrom in trachea at the height of cricoib cartilage was reported.
    Since his birth, the parents noticed that he was suffered from stridor. And, one day when he was 2 year old, he was attacked by sudden dyspnea.
    Under the X-ray examination and direct laryngoscopical examination, we could diagnose his case as chondrom which was grown inside of trachea at the height of cricoid cartilage.
    After the tracheotomy, removals of this chondrom was performed under the vertical incision on the cricoid cartilage.
    Histolological examination of the removed specimens was shown to be hyaline chondrom which originated from cricoid cartilage.
    We succeeded in the complete closing of incised part of the cricoid cartilage. And, after one and half year, we could also get the permanent cicsure of his tracheostoma.
  • 弓削 庫太, 服部 康夫, 村上 享司, 中村 兼一, 中村 賢, 児玉 駿一郎, 村上 忠也, 渡辺 充, 物集女 誠治, 和田 忠男, ...
    1977 年 28 巻 4 号 p. 263-268
    発行日: 1977/08/10
    公開日: 2010/10/20
    ジャーナル フリー
    We reported two cases of right upper lobe bronchial anomaly which had experienced recently.At both cases, upper bronchus (apical bronchus) was found to be originating from trachea, and from little upper right side wall of trachea than bifurcation. The first case was confirmed by bronchoscopy, the second case by X-ray tomography. Both cases were displaced bronchus, what you called, tracheal bronchus. Tracheal bronchus of the first case was consisted of Bi+ BB, the second was B1.
  • 大野 政一, 貴島 徳昭
    1977 年 28 巻 4 号 p. 269-273
    発行日: 1977/08/10
    公開日: 2010/10/20
    ジャーナル フリー
    Department of Otolaryngology, Kagoshima University School of Medicine, Kagoshima Three cases of stridor in children are reported from the otolaryngologic aspect. The cases included'a case of acute epiglottitis, tracheal granuloma and foreign body (fish bone) imbedded for a long time in the larynx. When a foreign body is suspected in the larynx by detailed questioning, direct laryngoscopy is required. Acute epiglottitis is not only a local inflammation but is accompanied by septicemia-like symptoms. In severe cases, in which a sudden change occurs emergency tracheotomy may be necessary. For this reason, the general practitioner should know and be fully aware of this condition. Tracheal granuloma is a condition which should be watched for, especially when removing the tube after tracheotomy. The above conditions should be kept in mind by otolaryngologists when stridor is encountered in children.
  • 高浪 巌, 石原 恒夫, 菊地 敬一, 井上 宏司, 深井 志摩夫, 武士 昭彦, 小川 純一, 前中 由己
    1977 年 28 巻 4 号 p. 274-278
    発行日: 1977/08/10
    公開日: 2010/10/20
    ジャーナル フリー
    Three Cases of tracheal stencsis due to metastasis to paratracheal and paraesophageal lymphnodes from esophageal carcinoma were reported.
    Though the most common symptom associated with esophageal carcinoma is dysphagia, chiefcomplain of the 3 cases was dyspnea followed by hoarseness. When patients have dyspneawithout dysphagia, it is usually delayed to be diagnosed esophageal carcinoma, because trachealobstruction is a life-threatening emergeney that requires immediate therapy.
    The first patient had dyspnea and hemoptysis followed by hoarseness. Bronchoscopic examinationdisclosed carcinoma which occluded the lumen of the mid-trachea. Nine tracheal ringswere resected and a primary anastomosis was carried out. After operation, esophagographyshowed filling defect of middle third of esophagus due to carcinoma.
    The second patient complained of worsening dyspnea and hemoptysis followed by hoarseness.A tracheostomy was carried out immediately, and a tracheal tube was inserted. Tomogramsconfirmed tracheal narrowing above the carina, so diagnosed the mediastinal tumor that compressedthe frachea. An emergency operation to excise the tumor was performed. Microscopic examinationshowed that the tumors was metastatic lymph nodes of squamous cell carcinoma.After operation, esophagography showed filling defect of lower esophagus due to carcincma.
    The third patient was admitted for dyspnea and dysphagia followed by hoarseness. Bronchoscopyshowed a circumferential constriction 5 cm below the cords. Dyspnea was not so severethat he received 6000 rads of Linac. Brushing the lumen of the pcsterior wall of the occludedtrachea yielded the diagnosis of squamous cell carcincma. Esophagography showed stenosis ofmiddle third of esophagus due to carcinoma.
    The first presenting symptom was hoarseness, but at that time they were diagnosed as idiopathic paralysis of recurrent laryngeal nerve. When paralysis of recurrent laryngeal nerveappears, the true cause must be sought for by means of chest x-ray film, tomography and endoscopic examination of the trachea and esophagus.
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