In order to confirm that the total esophagectomy without thoracotomy (blunt dissection) is, the good indication for hypopharyngeal and cervico-esophageal cancer, this malignancy was clinico-pathologically investigated. (
Patients and Methods): In 25 patients with hypopharyngeal, cervico-esophageal and laryngeal cancer, blunt dissection was performed at our hospital between 1983 and 1988. The clinical data of these cases were reviewed to examine the morbidity and mortality of this operative procedure. The resected specimens of seventeen patients with squamous cell carcinoma of hypopharynx or cervical esophagus being received total esophagectomy were stained with Lugol's solution and totally sliced transversely after formalin-fixation. All the slices were histologically examined. (
Results): The mean volume of the operative bleeding was 900 ml. The post-operative complications were relatively rare and not serious. Only one case died within 30 days after the operation. Another cancerous lesions were pathologically detected in thoraco-abdominal esophagi in 8 cases (47%). Atypical epithelia were histologically found out apart from main tumors in 13 cases (76%); severe dysplasia, 5 cases (29%), moderate, 6 (35%) and mild, 1 (6%). Twelve cases (71%) among them were complicated with multiple cancer or severe dysplasia. On the other hand, in all the female patients, another cancerous or dysplastic change was not seen. (
Conclusion): Blunt dissection was considered to be the safe operative procedure, with rare serious complications and low mortality rate. Carcinoma of the hypopharynx and cervical esophagus was frequently complicated with another cancerous or severe dysplastic lesions in the thoraco-abdominal esophagus particularly in the male patients. Total esophagectomy was necessary for these cases to improve the prognosis.
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