巻号一覧
47 巻 (1996)
- 6 号 p. 483-
- 5 号 p. 421-
- 4 号 p. 365-
- 3 号 p. 277-
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47 巻, 6 号
選択された号の論文の8件中1～8を表示しています
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山形 和彦, 湯本 英二, 河北 誠二, 相原 隆一, 河村 裕二1996 年 47 巻 6 号 p. 483-490
発行日: 1996/12/10
公開日: 2010/10/20
ジャーナル フリーWe investigated the subneural apparatus (SNA) of the cricothyroid (CT), thyroarytenoid (TA) and posterior cricoarytenoid (PCA) muscles in an adult rat using scanning electron microscopy. The excised muscle was fixed in 3% glutaraldehyde and postfixed in 1% osmium tetraoxide. The specimen was subsequently treated with 8N - HC1 for 30 minutes at 60°C to remove the intramuscular connective tissue components. A histochemical study of the fibers, a myosin ATPase stain, in the three muscles was also performed. All of the primary synaptic clefts observed in the TA and PCA muscles were of the depression type, while those in the CT muscle consist of both depression and labyrinthine type. Furthermore, we classified the depression type SNA into two types, one with a predominance of the slit type (Ds type) and the other a mixture of the slit and pit types (Dmix type), based on differences in the appearance of the secondary synaptic cleft. In contrast, the labyrinthine type SNA consisted of a single component, a predominantly slit-type (L type). Of these three SNA types, two were found in the TA and PCA muscles, while the CT muscle showed the three types of SNA. Two types of muscle fiber, type 1 and 2B fibers, were differentiated in the three different kinds of muscles. In the TA and PCA muscles, the fact that proportion of each of the SNA types was equal to that of each of the muscle fiber types indicated that the SNA of the type 1 muscle fiber corresponded to the Dmix type, and that of the type 2B fiber corresponded to the Ds type. In the CT muscle, assuming that both the Ds and L types served as the SNA of the type 2B muscle fiber, the proportion of the Ds and L types to the total number of the SNA was nearly equal to the proportion of type 2B muscle fibers. In conclusion, we inferred that each type of muscle fiber had a specific type of SNA in the case of the intrinsic laryngeal muscles of the adult rat.抄録全体を表示PDF形式でダウンロード (2661K) -
再手術例の検討箕山 学, 田辺 正博, 田中 信三1996 年 47 巻 6 号 p. 491-496
発行日: 1996/12/10
公開日: 2010/10/20
ジャーナル フリーBetween 1988 and 1995, 54 patients underwent laryngeal framework surgery, to treat glottal insufficiency due to unilateral vocal cord paralysis at Osaka Red Cross Hospital. Thyroplasty type I was performed initially in 33 patients, arytenoid adduction was performed in 18 patients, and combined thyroplasty type I and arytenoid adduction was performed in 3 patients. To date, 5 patients who had poor results from their initial surgery have undergone revision laryngeal framework surgery. Three patients who initially underwent arytenoid adduction underwent revision thyroplasty type I as a secondary procedure. Patients with vocal cord atrophy initially had to undergo combined thyroplasty type I and arytenoid adduction. Two patients who initially underwent thyroplasty type I underwent revision thyroplasty type I, with placement of a larger silicon block implant. At surgery, the tissue adjacent to the previously implanted silicon block exhibited the formation of a thin fibrous capsule. The silicon block implant was easily removed and replaced with a different, largersized, silicon block implant. The results of the revision surgery were satisfactory in all five patients.抄録全体を表示PDF形式でダウンロード (5108K) -
浦野 誠, 岩田 重信, 高須 昭彦, 桜井 一生, 森 茂樹, 小森 克彦, 加藤 久幸, 加藤 小百合, 黒田 誠1996 年 47 巻 6 号 p. 497-504
発行日: 1996/12/10
公開日: 2010/10/20
ジャーナル フリーThe immunohistochemical expression of p53 and cyclin D1 proteins was evaluated in formalin-fixed, paraffin-embedded surgical specimens from 39 patients with epithelial hyperplasia and dysplasia of the vocal cords. The series for this study consisted of nine patients with hyperplasia, 12 with mild dysplasia, ten with moderate dysplasia, eight with severe dysplasia, eight with vocal cord polyps, and 14 with invasive squamous cell carcinoma (SCC).
The following results were obtained. 1) The mean p53 positive rates were 0.81±0.37 (mean±STD%) in mild dysplasia, 5.56±1.18 in moderate dysplasia, 11.81±3.61 in severe dysplasia, and 39.23±12.78 in SCC. The p53 expression was negative in the polyp cases and mild dysplasia. 2) The mean cyclin D1 positive rates were 0.55±0.15 (mean±STD%) in hyperplasia, 5.16±1.53 in mild dysplasia, 8.02±5.25 in moderate dysplasia, 18.34±8.95 in severe dysplasia, and 32.20±17.77 in SCC. The cyclin D1 expression was negative in the polyp cases.
In the cases of hyperplasia and dysplasia, the p53 and cyclin D1 positive rates increased significantly as the histological grade advanced (p <0.05). Some cases which recurred or progressed to cancer showed a significantly higher expression of p53 and cyclin D1 than the mean value for each lesion type.
In the cases of SCC, there was no significant correlation between the p53 or cyclin D1 positive rates and either the degree of tumor cell differentiation or the T-classification. The p53 positive rates correlated with the cyclin D1 positive rates in all cases.
These results suggest that a high expression of p53 and/or cyclin D1 may be associated with the recurrence and progression to malignancy in the precancerous lesions of the vocal cords seen in epithelial hyperplasia and dysplasia.抄録全体を表示PDF形式でダウンロード (3578K) -
術前非照射例との比較検討落合 正宏, 新井 一史, 今津 浩喜, 谷口 正美, 船曵 孝彦1996 年 47 巻 6 号 p. 505-509
発行日: 1996/12/10
公開日: 2010/10/20
ジャーナル フリーTo evaluate the influence of radiotherapy upon tumor cells from esophageal carcinoma, a cytokinetic study was made to compare those with and without pre-operative irradiation using resected specimens.
In the pre-operatively irradiated group (R group), the average dosage of irradiation was 36.5±11.5 Gy, and the intervals between the end of radiotherapy and the day of surgery ranged from two to three weeks in all cases.
Using paraffin-embedded materials, AgNOR numbers, a PCNA labeling index, and a positive ratio of immunohistochemical staining of ornithine decarboxylase (ODC) in tumor tissues, the R group and non-irradiated group (NR group) were examined. The non-cancerous epithelium of the non-irradiated patients were examined as well as a control (C group). Post operative survivals were assessed for clinical evaluation in stages 3 and 4 of both R and NR patients.
As a result, the AgNOR numbers were 5.5±1.2 in the R, 5.6±0.8 in the NR and 2.3±0.4 in the C groups. Statistical difference was noted between the R and C groups, as well as between the NR and C groups. However, no difference was seen between the R and NR groups. PCNA L. I. was 72.6±13.8% in the R, 79.3±8.0% in the NR and 51.7±5.7% in the C groups. The statistical analysis gave the same results as the AgNOR study. The positive ratio of the ODC staining was 26.1% in the R and 48.6% in NR, whereas there was no positive in the C group. No statistical difference was seen between the R and NR groups either.
Post-operative survivals of stage 3 and stage 4 patients of both the R and NR groups was almost the same.抄録全体を表示PDF形式でダウンロード (1059K) -
岩田 重信, 三嶋 由充子, 西村 忠郎, 川勝 健司, 石神 寛通, 佐藤 達明, 斉藤 路子, 宮沢 享司, 馬場 駿吉, 高木 一平, ...1996 年 47 巻 6 号 p. 510-525
発行日: 1996/12/10
公開日: 2010/10/20
ジャーナル フリー434 cases (216 males and 218 females) of esophagus and 182 cases (118 males and 64 females) of broncho-tracheal foreign bodies gathered from the ENT departments of 7 universities located in the Tokai area of Japan were statistically analyzed during past 10 years. As esophageal foreign bodies, PTP (35.1%) ranked first, followed by coins (24.0%), peaces of meat (10.9%), and fish bones (10.0%). In regard to broncho-tracheal foreign bodies, 75.1% of all cases were under 3-year-olds patients. Transluscent foreign bodies were found in 86.3% of all cases. The foreign bodies were beans in 68.1% of all cases, followed by artifical teeth in 11.5%. The foreign bodies were lodged in the right bronchas with the same frequency as in the left. In this study, PTP foreign bodies have occurred most often in the esophagus recently, and the discussed the prevention of PTP foreign bodies in this paper.抄録全体を表示PDF形式でダウンロード (3296K) -
Toshiyuki Katoh, Yoshinori Kawabata, Yasuhiro Kondoh, Hiroyuki Taniguc ...1996 年 47 巻 6 号 p. 526-533
発行日: 1996/12/10
公開日: 2011/08/10
ジャーナル フリーAcute interstitial pneumonia (AIP), bronchiolitis obliterans organizing pneumonia (BOOP), and acute exacerbation of idiopathic pulmonary fibrosis (IPFex) all present with acute onset and a rapidly progressive clinical course. Since it is sometimes difficult to differentiate among these three entities, the present study was designed to analyze differences.
Four AIP, seven BOOP, and eight IPFex patients were studied clinically and pathologically with semi-quantitative scoring methods using immunohistochemistry.
Clinically, there were no significant differences, except that the patients with BOOP had lower chest roentgenogram scores and lung injury scores (p < 0.05 ).
Pathologically, the mean epithelial basement membrane damage score in the AIP patients was higher than that of the other patients (p <0.05). Among the intraluminal organizing exudate scores, the polypoid type was highest in the BOOP patients (p <0.01), and the incorporative/obliterative type was highest in the AIP patients (p < 0.005). The epithelial basement membrane damage scores correlated with the intraluminal organizing exudate scores (polypoid type, r = -0.57 ; incorporative/obliterative type, r = 0.81).
Although there are clinical similarities among the three disorders, pathological differences also exist and are demonstrated by the present findings.抄録全体を表示PDF形式でダウンロード (3858K) -
超音波検査法の有用性について篠原 尚吾, 庄司 和彦, 児嶋 久剛, 宮田 耕志, 山本 典生1996 年 47 巻 6 号 p. 534-538
発行日: 1996/12/10
公開日: 2010/10/20
ジャーナル フリーIn this study, preoperative localization of parathyroid adenomas by ultrasonography (US), computed tomography (CT), magnetic resonance imaging (MRI), 201Tl/99mTc (or 123I) subtraction scintigraphy (SS) and 99mTc-sestamibi (MIBI) scintigraphy were compared in 20 patients with primary hyperparathyroidism. The sensitivities for the detection of adenomas were 75% on US, 77.8% on CT, 69.2% on MRI, 72.2% on SS and 72.7% on MIBI. In 7 patients with thyroid disease or a cyst in another parathyroid gland, the sensitivities for detection were quite poor while the sensitivity was 100% on US in the remaining 13 patients. We concluded that the appropriate procedure for imaging parathyroid adenomas to be as follows. US should be performed first with either scintigraph used as a supplement. CT or MRI are not necessary unless other lesions in the thyroid or parathyroid glands are found on the US.抄録全体を表示PDF形式でダウンロード (2699K) -
甲状軟骨形成術の応用三枝 英人, 潮 建司朗, 國友 万由美, 新美 成二, 八木 聰明1996 年 47 巻 6 号 p. 539-544
発行日: 1996/12/10
公開日: 2011/08/10
ジャーナル フリーArytenoid subluxation is rare in laryngeal trauma. We report the case of a patient who had been complaining of hoarseness, dysphagia and aspiration caused by the antero-medial subluxation of the right arytenoid cartilage. Fiberscopic findings revealed that the right arytenoid cartilage moved antero-medially during phonation. As a surgical treatment, we designed a trianguler cartilage plug collected from the thyroid cartilage. This plug was inserted through the edge of the thyroid cartilage and fixed to the inner surface of the thyroid cartilage by the fibrin paste. After the operation, the arytenoid cartilage was fixed at the median position and glottal closure was improved.抄録全体を表示PDF形式でダウンロード (1590K)
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