The purpose of this study was to compare the long-term clinical outcomes after implantation of drug-eluting stents (DESs) in patients with coronary artery disease (CAD), prior cerebral infarction with or without peripheral artery disease (PAD). Forty-nine consecutive patients (69 lesions) who underwent successful coronary DES implantation were prospectively classified into two groups: those with a PAD (PAD group, 13 patients, 18 lesions) and those without a PAD (non-PAD group, 36 patients, 51 lesions). The primary endpoint was defined as death, nonfatal myocardial infarction, and cerebrovascular events. The Kaplan–Meier method was used to create the primary endpoint curves to determine the time-dependent cumulative primary endpoint-free rate, which were compared using the log-rank test. The incidence of primary endpoints was higher in the PAD group than in the non-PAD group (p=0.0110). The results showed that clinical outcomes were poorer in patients with CAD, prior cerebral infarction who had PAD than in those who did not have PAD.
A 54-year-old woman with fever and diarrhea was treated as colitis by the previous doctor. She was referred to our hospital without improvement. The blood test showed markedly increased eosinophil count. CT examination showed the thrombosis of the superior mesenteric vein, abdominal aorta, and right pulmonary artery. We diagnosed as eosinophilia with multiple thrombosis. We started anticoagulant and steroid therapy. Eosinophil counts decreased, and CT at 3 months after the onset showed reduction of the thrombosis. We have been decreasing the amount of the steroid, and did not detect the recurrence of the thrombosis.