Recently, remarkable progress has been made on the remote results in the cases operated on colorectal carcinoma, and those participating factors are operation-technique, deeply reaching degree, metastasis to lymphatic nodes and remote metastasis. However, similar to the conventionaldiscussion on benign tumor, there is less report of statistical observation considering the defensive factors in view of the bio-antitumorous nature. We have, therefore, noticed the interstitial reaction at the border-face between the cancer-focus and the normal tissues, namely, the fibrillation and the appearance of the wandering cells, thus we reviewed the remote results of surgical cases on colorectal cartinoma.
In our clinic, 35 caces were surveyed on the relationship between histological findings and prognosis in the patients treated with the operation for colorectal carcinoma in the period from 1959 to 1969, and we have reviewed the factors which seem to influence on the prognosis by means of our devised diagram-method. As a result, the appearance of the wandering cells was proved to be a very important factor of prognosis.
As the kinds of the wandering cells, we have noticed the nature lymphocytes, neutrocytes, plasma-cells, eosinophilic cells, fibroblasts, monocytes (containing rather big cells with fine cells of round reticular cells, lymphoblasts, and histocytes), as well as mastcells, thus we have reviewed these cell'incidence and distribution.
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