Nihon Daicho Komonbyo Gakkai Zasshi
Online ISSN : 1882-9619
Print ISSN : 0047-1801
ISSN-L : 0047-1801
Volume 53, Issue 2
Displaying 1-11 of 11 articles from this issue
  • In Reference to Combination of Antibiotecs and Duration of Administration
    S. Osada, S. Ono, S. Aosasa, C. Ueno, H. Mochizuki
    2000 Volume 53 Issue 2 Pages 63-69
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
  • M. Matsumoto, M. Maruta, K. Maeda, T. Utsumi, Y. Koide, K. Senda, O. I ...
    2000 Volume 53 Issue 2 Pages 70-75
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    To evaluate a change of defecatory function after resection of sacral tumor, clinical assessment and manometric studies were performed. Four cases with sacral tumor (two cases of neurinoma and two cases of chordoma) were studied in anorectal manometry and questionnaires pre-and postoperatively. Male to female ratio was 1:1 (two cases each), and the mean age was 40 years. Radicular resection was done in three cases, and the sacral nerve roots were preserved in one case. One case underwent bilateral radicular resection under L5, another case bilateral resection of S2, 3, and 4, and the last case unilateral resection of S2 and 3. HPZ, MRP, RW, MSP, RAR, FS and MTV were measured by anorectal manometry using a micro-tip transducer by a station pull-through technique. The condition of defecation was assessed by questionnaire. Frequency of defecation per day, consistency of stool, defecation sensation, discrimination between feces and gas, state of continence and urgency were evaluated.
    Defecatony function was destroyed in one case that underwent bilateral radicular resection. However, defecation was maintained by controlling fecal consistency in spite of some changes in manometric studies in cases with unilateral radicular resection and radicular preservation.
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  • T. Miyashita, G. Nishimura, K. Taniguchi, T. Yasui, E. Bando, S. Fushi ...
    2000 Volume 53 Issue 2 Pages 76-82
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    Serum CEA, CYFRA21-1, IAP and CA19-9 levels in 125 cases of primary colorectal cancer were studied. Among the four tumor markers the highest positive rate was observed in CEA, indicating 39.2%. The combination assay raised the positive rate, showed 54.4% for CEA and CYFRA21-1, 63.2% for CEA, CYFRA21-1 and IAP, and 65.5% for the 4 tumor markers. There was correlation between liver metastasis and the positive rate of each marker, peritoneal dissemination and that of serum CYFRA21-1, nodal involvement and that of serum CYFRA21-1 or CA 19-9. The survival rate for patients in the positive group of each marker was lower than that in negative group. These findings suggested that evaluation of serum CEA, CYFRA21-1, IAP and CA19-9 levels in colorectal cancer might be helpful in staging the cancer and estimating the prognosis.
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  • S. Takamura, T. Sakuyama
    2000 Volume 53 Issue 2 Pages 83-90
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    To evaluate predictive factors for hematogenous metastasis from colorectal cancer, we performed immunohistochemical study using CEA stain and PyNPase stain of surgical speciemens from 100 patients with colorectal cancer including 50s with hematogenous metastasis and 50s without metastasis. Univariate analysis showed multiple important factors which were tumor size, tumor depth, venous invasion, lymph node metastasis, CEA stain and PynPase stain. But multivariate analysis disclosed, the most significant factor was PyNPase stain (p=0.0007, Odds ratio: 14.75), and the 2nd significant factor was distribution of CEA stain (p=0.0085, Odds ratio: 5.71). These observations suggest that these immunochemical stainings were important predictive factors for hematogenous metastasis from colorectal cancer.
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  • M. Fukuda, K. Nagao, M. Matsuda, H. Miyayama
    2000 Volume 53 Issue 2 Pages 91-95
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    A case of amelanotic malignant melanoma of the sigmoid colon is reported.
    This patient was a 49 year-old female, complaining of abdominal pain and bloody stool. Colonoscopic study revealed a 4 cm diameter tumor of the sigmoid colon. Though the specimen from biopsy was Group 1, malignant disease was suspected. Sigmoidectomy with lymph node dissection was performed. The pathological examination failed to confirm it because the tumor color was not black. The immunohistochemical study revealed it was amelanotic malignant melanoma.
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  • S. Marubashi, T. Monden, H. Yano, S. Matsui, Y. Nakano, H. Tateishi, M ...
    2000 Volume 53 Issue 2 Pages 96-99
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    A case of sigmoid colon cancer with submucosal invasion is reported. A 46-year-old female was referred to our hospital because of diarrhea, occult blood in feces and anemia. Colonoscopic examination revealed Is-like polyp, which was ca. 3 mm long, in the sigmoid colon. Endoscopic mucosal resection (EMR) was performed. It was histologically well-differentiated adenocarcinoma without adenoma component, and the tumor invaded to the cut end. Therefore, additional surgery, laparoscopy-assisted sigmoidectomy with dissection of Group 1 and 2 lymph nodes was performed. Moderately-differentiated adenocarcinoma with deep submucosal (sm3) invasion remained in the specimen. Group 1 lymph node was involved. It is reported that most colorectal carcinomas with submucosal invasion whose size are less than 5 mm belong to the superficial type. No colorectal carcinoma with submucosal invasion whose size is less than 5 mm like ours has ever been reported before. It was speculated that the tumor arose as de novo carcinoma, developed as a protruded type and invaded into the submucosal layer in the early stage of its development.
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  • M. Miyoshi, Y. Ogata, Y. Akagi, K. Yamazaki, A. Ohkita, J. Kaibara, M. ...
    2000 Volume 53 Issue 2 Pages 100-104
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    A family in which the eldest male sibling suffered from Crohn's disease and a brother and sister suffered from ulcerative colitis was reqorted. The 35-year-old male and 33-year-old female underwent surgery, while the 29-year-old male was treated conservatively. HLA typing of the older brother with Crohn's disease was A2, A24, B59, B61, Cw1, Cw3, and DR4. The HLA typing of the two siblings with ulcerative colitis was very similar, with A2, A24, B52, B61, Cw3, and DR2. The HLA typing in our cases demonstrated that DR4 was specific to Crohn's disease, while B52 and DR2 were specific to ulcerative colitis. However, in this and 5 other reported cases of Crohn's disease and ulcerative colitis analyzed using HLA typing, a correlation between the development of the disease and the HLA typing has been found. It was suggested that further analysis of genetic factors should be carried out to clarify the pathogenesis of the disease.
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  • H. Tsutsumida, K. Ibusuki, A. Yamamoto, S. Taniguchi, K. Koga
    2000 Volume 53 Issue 2 Pages 105-109
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    Appendiceal mucocele is rare. A case of appendiceal mucocele in hemodialysis patient that could be diagnosed and treated by laparoscopic appendectomy.
    A 83-year-old female with hemodialysis was admitted to our hospital because of right lower abdominal pain. Plain X-ray film of the abdomen and computed tomography of the abdomen, barium enema indicated appendiceal mucocele or ovarian tumor, but diagnosis could not be done and her pain could not be controlled. Since she was old and of undegoing hemodialysis, a major operation of high risk was not selected. Thus laparoscopy was performed and diagnosis was easy and appendiceal mucocele was resected.
    Laparoscopic appendectomy is very useful for high risk case of appendiceal mucocele.
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  • K. Mizukami, T. Takashima, H. Ohtani, Y. Fukunaga, S. Tanimura, Y. Fuj ...
    2000 Volume 53 Issue 2 Pages 110-115
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    A total of 55 patients with liver metastasis from colorectal cancer underwent curative hepatectomy (65 times hepatecomies) in the past 16 years, and the prognostic factors related to long survival after hepatectomy and the significance of repeated resection of recurrent foci after hepatectomy were investisated. The 50% survival periods of 55 patients were three years and four months. On the basis of this investisation, five factors, the number of metastatic liver tumors, presence of residual liver recurrence, presence of lung metastasis, n-factor and histological type of original lesion in 21 patients who survived more than three years and 17 patients who died within three years after hepatectomy were studied. In 11 patients who survived more than three years after hepatectomy having recurrence, six patients underwent reoperation and five patients did not, and the five-year suvival rates were 80% and 20%, respectively. Therefore, a significance of reoperation for recurrence in long survivors was recognized. The five-year survival rates of the three groups histologically classified as well-differentiated type, moderately-differentiated type and poorlydifferentiated type were 67%, 38% and 0 %, respectively. The well-differentiated type seemed to show excellent prognosis, and the 10 year survival rate of 14 patients with well-differentiated type in the H1 groun and solitary lesion was 75 %. so a'ood nroe'nosis by suraerv alone can be expected.
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  • N. Oshitani, D. Kawashima, M. Inagawa, M. Sogawa, M. Iimuro, Y. Jinnno ...
    2000 Volume 53 Issue 2 Pages 116-122
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    There have been several arguments whether simple ulcer of the ileocecal region and intestinal Behcet's disease are identical or different disease entities. Nine patients with intestinal Behcet's disease and 4 patients with simple ulcer were studied. There were 8 males and 1 female patients with intestinal Behcet's disease, and the mean age of onset was 34 years. There were 3 males and 1 famale patients with simple ulcer, and the mean age of onset was 39 years. Intestinal ulcers were confined to the ileocecal region in all but are of the patients with simple ulcer ; aphthoid ulcer was found in the rectum in addition to ascending colon ulcer. However, intestinal lesions spread more widely in patients with intestinal Behget's disease, characterized by aphthoid ulcers in the ileum, colon, and rectum. Symptoms of Behget's disease were not observed in patients with simple ulcer even during the follow-up period. Intestinal ulcers in patients with Behcet's disease tended to require frequent hospitalization and necessitate more surgical treatment in contrast to those in patients with simple ulcer.
    It was concluded that simple ulcer and intestinal Behcet's disease are different categories of inflammatory disease.
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  • 2000 Volume 53 Issue 2 Pages 123-129
    Published: 2000
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    Download PDF (699K)
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