Nihon Daicho Komonbyo Gakkai Zasshi
Online ISSN : 1882-9619
Print ISSN : 0047-1801
ISSN-L : 0047-1801
Volume 54, Issue 8
Displaying 1-10 of 10 articles from this issue
  • K. Oyama, G. Nishimura, T. Ohta, K. Shiozawa, I. Ninomiya, S. Fushida, ...
    2001 Volume 54 Issue 8 Pages 545-550
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    It has previously been demonstrated that some solid cancer cells express Fas-ligand and can kill lymphoid cells by Fas-mediated apoptosis.. This "counterattack" has a potential mechanism of immune privilege that plays important roles in tumor progression in various malignancies. We thus studied 77 samples of surgically resected human colorectal cancers by immunohistochemical staining. Of those colorectal cancers, 42.9 % stained positively. The expression of Fas-ligand correlated significantly with the presence of liver metastasis (p<0.001), nodal metastasis (p=0.027), clinical stage (p=0.009), and recurrence.in the liver (p=0.001). Furthermore, in multivariate analysis, recurrence in the liver was significantly associated with Fas-ligand expression. These findings suggested that Fas-ligand is expressed in colorectal cancers and plays critical roles in tumor progression, especially in liver metastasis, and that Fas-ligand expression might be helpful in estimating recurrence in the liver.
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  • K. Iwakawa, S. Kajiwara, Y. Kamei, Y. Ono, Y. Hachisuka
    2001 Volume 54 Issue 8 Pages 551-556
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    We report a 70 year-old-women with adenocarcinoma arising in a tailgut cyst. In an investigation of fever and polyarthralgia, CT showed a cystic mass in the retrorectal space. The lesion was excised through the transabdominal approach. The pathological findings were compatible with a tailgut cyst with ciliated columnar epithelium. Three years later, follow-up CT and MRI revealed local recurrence, which was resected through the trassacral approach. The resected specimen showed adenocarcinoma limned with columnar epithelium continuously, invading the full thickness of the wall. Abdominosacral resection of the rectum combined with sacral resection (S3-4) was performed. The resected specimen showed remnant malignant tumor in the presacral space. Presacral cystic tumor should be excised early and completely, keeping in mind that a tailgut cyst may have malignant potential.
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  • T. Tanaka, T. Ryu, M. Takazoe, Y. Shimamura, K. Makimoto, T. Takahashi ...
    2001 Volume 54 Issue 8 Pages 557-561
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    Deep venous thrombosis (DVT) has been recognized as a rare but serious complication of inflammatory bowel disease (IBD). A 21-year-old woman with a 4-year history of ileo-colonic Crohn' s disease was admitted for severe anemia and malnutrition. Abdominal CT demonstrated a large thrombus of the inferior vena cava. In barium enema studies, severe ulceration, narrowing, and shortening were observed from the rectum to the transverse colon, compared with studies performed two years previously. A vena cava filter was inserted, and an anticoagulant was administered. Follow-up CT showed the thrombus was markedly reduced and calci-fied. Neither inherited abnormalities of coagulation proteins nor anticardiolipin antibodies were found. She had no family history of thromboembolism. DVT may be caused by thrombocytosis, hypercoagulable states, and dehydration associated with exacerbation of Crohn' s disease.
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  • H. Takamiya, Y. Yamashita, A. Iwashita
    2001 Volume 54 Issue 8 Pages 563-568
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    E. Coli, which produces Verotoxins, causes serious enteritis. We successfully treated two patients with O157:H7 hemorrhagic colitis, who were chronologically investigated by colonoscopy and barium enema. The two patients were women, of ages 55 and 64. Their chief complaints were abdominal pain, diarrhea, and bloody stools. Total colonoscopy and barium enema performed soon after hospitalization indicated edema and hemorrhagic erosion of the colonic mucosa. These findings had almost disappeared before each patient's discharge from the hospital. First colonic mucosa biopsy specimens showed richly fibrous exudates, hemor-rhaging, hyperemia, mild neutrophilic infiltrates, goblet cell depletion, and focal desquamation of surface epithelium. It was considered that early diagnosis and treatment of O157 : H7 E. Coli hemorrhagic colitis would be possible not only by a detailed history of the symptoms and signs, but also by investigation using colonoscopy and barium enema.
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  • H. Aoyama, M. Maruta, K. Maeda, K. Masumori, Y. Koide, K. Inukai, R. K ...
    2001 Volume 54 Issue 8 Pages 569-574
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    Extensive Perineal hemangioma is rare. Only one case has been reported in the Japanese literature. We herein report a case of a very extensive perineal hemangioma, which extended from subcutaneous tissue of the penis to the rectal wall in the pelvic cavity.
    An 18-year-old man visited our hospital with anal pain, anal bleeding, and remittent fever. Helical CT, MRI, and angiography revealed a very extensive perineal hemangioma in the subcutaneous tissue of the penis, perineoscrotum, submucosa of the anus, rectal wall, and pelvic cavity. Complete excision of the tumor. was considered impossible due to its extensive growth. Other possible treatment modalities ; radiation, laser, compression, cryotherapy, and embolization of the feeding artery, were abandoned as well, due to their incompleteness of treatment. Finally, we selected conservative observation, because his compliant is controllable by maintaining the stool loose and using ointment for his anus. He is enjoying daily life in a university without sufferings from symptoms associated with his perineal hemangioma.
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  • K. Tsuchiya, O. Doi, H. Yoshida, H. Tamekiyo
    2001 Volume 54 Issue 8 Pages 575-578
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    A 57-year-old man was referred for total colonofiberscopy. At 6 minutes after the start of the colonofiberscopy, the patient suddenly developed acute cardiac failure. He was resuscitated with coronary dilators (Isosorbid nitrate). Right coronary artery spasm was proved by coronary angiography, which was induced with acetylcholine. Acute cardiac failure, which occurred during colonofiberscopy, was supposed to have been caused by right coronary artery spasm. Careful consideration, including coronary care, is necessary during colonofiberscopy.
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  • T. Fukushima, K. Koganei, M. Shinozaki, F. Kito, M. Takahashi, M. Ohta ...
    2001 Volume 54 Issue 8 Pages 579-582
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
    Seven (1.0%) out of 680 patients with ulcerative colitis treated at Yokohama City Hospital died between Aug. 1993 and Feb 2001. They were 5 males and 2 females with a mean age of 44.7 years. Three died from colonic malignant diseases (2 colonic cancers, 1 carcinoid) and 4 died from postoperative complications. The patients that died from malignant disease had not received surveillance colonoscopy, and they died from liver metastasis and/or peritoneal dissemination. Four patients that died from postoperative complications had severe colitis. The postoperative mortality of severe colitis (9.8%, 4/41) was significantly higher than that of operated from the other reasons (0%, 0/190). The amount of prednisolone given within 1 month prior to surgery in the mortality group (1608±710mg) was significantly higher than that in the survived group (451 ±600mg). The cause of death was finally MOF. To reduce mortality, it is important to extend surveillance colonoscopy for the long standing patients and to avoid excess use of steroids preoperatively.
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  • T. Tabo, H. Hayashi, H. Onodera
    2001 Volume 54 Issue 8 Pages 583-584
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
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  • Y. Shibata
    2001 Volume 54 Issue 8 Pages 585-587
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
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  • 2001 Volume 54 Issue 8 Pages 588-600
    Published: 2001
    Released on J-STAGE: June 05, 2009
    JOURNAL FREE ACCESS
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