Journal of Flow Injection Analysis
Online ISSN : 2433-7374
Print ISSN : 0911-775X
Volume 25 , Issue 1
Showing 1-26 articles out of 26 articles from the selected issue
  • Foreword
    Tadao Sakai
    2008 Volume 25 Issue 1 Pages 1-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Download PDF (389K)
  • Foreword
    Toshio Yao
    2008 Volume 25 Issue 1 Pages 2-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Download PDF (167K)
  • Message
    Toshiyuki Hobo
    2008 Volume 25 Issue 1 Pages 3-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Download PDF (147K)
  • Review
    Marek Trojanowicz
    2008 Volume 25 Issue 1 Pages 5-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Review of current trends in miniaturization of instrumentation for flow analysis based on 84 literature references is presented, including design and applications of microfluidics, and use of nanostructures for detection purposes and design of nanofludics.
    Download PDF (1843K)
  • Original Paper
    Kunihiro Watanabe, Satoh Yasuo, Isao Shitanda, Masayuki Itagaki
    2008 Volume 25 Issue 1 Pages 15-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    A method was developed to determine anionic surfactants in river water using Teflon (PTFE) filter tube preconcentration. PTFE adsorbs hydrophobic and electrically neutral chemical species on its surface. This allows the surface of PTFE filter tube to adsorb and concentrate an ion pair formed between a cationic detecting agent and an anionic surfactant in aqueous solution. The detecting agent and the model anionic surfactant used were Co-5-Cl-PADAP, a highly sensitive detecting agent, and sodium dodecyl sulfate, respectively. After the ion pair was concentrated at a flow rate of 1.5mL/min for 5 min on a 7cm long filter tube (inner diameter: 1.5mm), the ion pair was eluted with ethanol at a flow rate of 2.0mL/min. The detection limit was 2ng mL-1 (3×standard deviation of blank). The sensitivity of this method was equal to or higher than that of the conventional solvent extraction method. This method and the Ethyl Violet method (EV method, JIS) gave somewhat different analytical results for a standard solution containing various anionic surfactants because the sensitivities of the methods are different for each surfactant, while they yielded the same analytical results for river water samples.
    Download PDF (1505K)
  • Original Paper
    Sri Chainulu, Shukla S.K, Sarma P.N
    2008 Volume 25 Issue 1 Pages 20-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    There is a continuing need for improved or new methods for the identification of compounds of forensic interest from forensic samples. Pyrethroids, though, widely used for pest control activities, has also been reported world wide from time to time involving its poisoning. We have developed Flow injection electrospray ionization tandem mass spectrometry as a rapid and powerful technique to identify pyrethroids (i.e. cypermethrin, deltamethrin and fenvalerate).
    Download PDF (246K)
  • Original Paper
    Andrey Bulatov, Yury Protsenko, Kristina Subbotina, Leonid Moskvin
    2008 Volume 25 Issue 1 Pages 24-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    The possibility of stepwise injection determination of analyzed substance in solutions by the standard additions method on example of determination of phosphate-ions in human urine has been shown. The automatic method for determination of phosphate-ions in human urine with the determination range of 2 to 12 mg/l and efficiency of 6 determinations per hour has been developed.
    Download PDF (192K)
  • Original Paper
    Idrees Al-Momani, Samer Kanan
    2008 Volume 25 Issue 1 Pages 29-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Spectrophotometric and chromatographic methods have been developed for the determination of doxycycline (DC), oxytetracycline (OTC) and chlortetracycline (CTC) in biological fluids and pharmaceutical preparations. Zirconyl chloride is proposed as a reagent for the spectrophotometric determination of the antibiotics under investigation. The reagent forms yellow 1:1 complexes with the drugs in acidic medium. The absorption maximum of the formed complexes was at 390 nm. The method has been adapted for flow injection analysis and successfully used for the analysis of these compounds in human blood plasma, urine and pharmaceutical preparations. For the chromatographic method, a reversed-phase C18 column with a mobile phase composed of 29.5% of acetonitrile and 70% of 0.1M oxalate buffer adjusted to pH 2.5 with 0.5 M sodium hydroxide and 0.5% triethyl amine was used. The proposed methods were successfully applied to the determination of the antibiotics under investigation in pharmaceutical preparations and biological fluids. The common excipients and additives did not interfere with their determinations. Extraction recoveries from synthetic mixtures were close to 100% at all concentrations, while extraction recoveries from spiked human plasma and urine samples varied between 93.1 and 97.7% and an RSD of less than 5.3%.
    Download PDF (207K)
  • Original Paper
    Takao Ohtomo, Shukuro Igarashi
    2008 Volume 25 Issue 1 Pages 35-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    The determination of trace (i.e. sub-ppb levels) ruthenium(III) was developed using catalytic reaction. In this reaction, copper(II)-phthalocyanine-3, 4', 4'', 4'''-tetrasulfonic sodium salt (Cu-PTS) as an indicator was decreased its absorbance by the oxidative decomposition with sodium periodate. Moreover, it was found that the reaction was extremely accelerated by adding ruthenium(III). Such catalytic reaction was applied to the flow injection analysis(FIA) of trace ruthenium(III). As results, the calibration curve of ruthenium(III) ion was linearly in the concentration range of 1 × 10-9 M to 1 × 10-7 M, and a sampling numbers per hour were 25 samples. Further, the relative standard deviation (RSD) was 0.75 % (n = 25) for Ru3+ 1×10-8 M, and the determination limits (3σ) of Ru3+ were 3.67× 10-10 M (37 ppt).
    Download PDF (292K)
  • Original Paper
    J. Rodriguez, G. Islas, M. Paez-Hernandez, E. Barrado
    2008 Volume 25 Issue 1 Pages 39-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    This paper reports a sequential injection spectrophotometric method for determining the concentration of diclofenac (DCF) in urine samples and pharmaceutical formulations. The method is based on the reaction of DCF with potassium permanganate in an alkaline medium. The influence on the analytical signal of the reactor length, the permanganate volume, the sample volume and the flow rate was investigated using a Taguchi parameter design. Under optimal conditions, the linear range of the calibration curve varied from 10.0 to 100.0 mg l-1, with a detection limit of 5.0 mg l-1. A sampling rate of 15 determinations h-1 was achieved; the relative standard deviation of analytical repeatability was less than 3.0% in all cases. The method was validated by comparing the results obtained against those provided by RP-HPLC; no significant differences were seen (p<0.05)
    Download PDF (246K)
  • Original Paper
    Efraim Reis, Jarbas Rohwedder, Célio Pasquini, Ronei Poppi
    2008 Volume 25 Issue 1 Pages 44-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    A system for continuous flow analysis with a voltammetric detector was developed, employing a multichannel polarograph, capable of operating with an assembly of 31 working ultramicroelectrodes (UMEs). The flow analysis system was based on the development of an EDTA gradient on a line containing the support electrolyte and Pb(II), Cd(II) and Tl(I) ions. With the differential complexation of each ion, promoted by the EDTA gradient, diferentiations in the voltamograms were observed, which makes possible the use of a multivariate calibration, since the investigated ions presented overlapping voltammetric waves.
    Download PDF (1273K)
  • Original Paper
    Suchada Chuanuwatanakul, Eakkasit Punrat, Janjira Panchompoo, Orawon C ...
    2008 Volume 25 Issue 1 Pages 49-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    An automated on-line preconcentration method was developed for simultaneous determination of Pb(II), Cd(II) and Zn(II) by square-wave anodic stripping voltammetry (SWASV) using bismuth film screen-printed carbon electrode (Bi-SPCE). The preconcentration of metal ions was performed with a mini-column of a chelating resin, which was installed on a switching valve in the automated system consisted of a syringe pump, an 8-port selection valve and a switching valve. The laboratory-assembled automated on-line pretreatment system (Auto-Pret ASV system) was controlled by the Visual Basic program written by the authors. The metal ions collected on the resin were eluted with 1 M hydrochloric acid, subsequently transported into the flow cell for on-line deposition of analytes on Bi-SPCE at -1.4 V vs. Ag/AgCl; then the flow of the solution was stopped and the voltammogram was recorded from -1.2 to 0.2 V vs. Ag/AgCl by scanning a potential in the square-wave waveform. Experimental conditions, such as pH of sample, a sample flow rate, an eluent volume and its flow rate were optimized. Under the optimum conditions, the analytical characteristics were studied. In addition, the proposed method was applied to the analysis of water samples.
    Download PDF (304K)
  • Original Paper
    Liliya Shpigun, Sergey Margolin, Marina Suranova
    2008 Volume 25 Issue 1 Pages 53-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    The present communication reports two simple flow injection (FI) methods for the determination of trace alloxan in biological matrices. The FI method for the amperometric determination of alloxan combines its chemical derivatization into dialuric acid by an amino thiol (L-cysteine, glutathione) and detection of dialuric acid at a glassy carbon electrode. The FI spectrophotometric method is based on the ability of alloxan to act as a ROS generator in the presence of unithiol followed by sequential detection of free radicals by means of formation of colored formazan from tetrazolium derivatives. The both proposed methods permit the automatic determination of ALX with good reproducibility and frequency (50 h-1). Validation was performed by recovery tests on synthetic samples.
    Download PDF (382K)
  • Original Paper
    Supaporn Hartwell, Jaroon Jakmunee, Somchai Lapanantnoppakhun, Kate Gr ...
    2008 Volume 25 Issue 1 Pages 57-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Telehealth and telemedicine are the approach to provide health care coverage to people in rural areas or patients who cannot conveniently travel to meet with doctors at a hospital. The telehealth system requires a multidisciplinary collaboration involving various sectors such as telecommunications, information technology, medical experts, hospitals, equipment suppliers and social workers. The advantages of automatic flow based systems in reducing the volume of sample, the analysis cost, the analysis time and the need of having highly trained personnel, make them suitable for use where the healthcare facility budget is inadequate. Therefore, flow based techniques have potential for applications in clinical analysis as part of the telehealth system in the developing countries.
    Download PDF (174K)
  • Original Paper
    Siripat Suteerapataranon, Daranee Pudta
    2008 Volume 25 Issue 1 Pages 61-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    A simple flow injection analysis-spectrophotometric system for the rapid determination of total polyphenols (TP) in tea extracts was developed. The method is based on Folin-Ciocalteu (FC) reaction, which involves the oxidation/reduction of polyphenolic compounds by FC reagent in alkaline medium, producing a blue molybdenum-tungsten complex. The linear range of the calibration graph was 10 – 500 mg gallic acid equivalent (GAE)/l. The relative standard deviation (RSD) (n=5) of the calibration graph was 2.93%. The precisions (%RSD, n=10) of the determination at low and high concentrations were 2.74% for the 10 mg GAE/l and 3.02% for the 500 mg GAE/l, respectively. The detection limit was 7 mg/l. The sample throughput was 30 per hour. The TP contents in tea extracts determined by the developed system were compared with those determined by the standard batch method and no significant difference was found (t test, at 95% confidence level).
    Download PDF (192K)
  • Original Paper
    Tursunjan Aydan, Ayumi Kitagawa, Masaki Takeuchi, Hideji Tanaka
    2008 Volume 25 Issue 1 Pages 65-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    We advanced the principle of feedback-based flow ratiometry to stepwise titration using two detectors set in tandem in a flow system. The method was applied to the simultaneous determination of calcium and magnesium ions (Ca2+ and Mg2+, respectively) by a chelatometry. The flow rate (FM) of titrand containing Ca2+ and/or Mg2+ was varied in response to controller output signals (Vc) having triangular wave profile, while the total (titrand + titrant + indicator solution) flow rate (FT) was held constant. Titrant solution (EDTA or EGTA, pH 10) was aspirated to the confluence point of the flow system at the flow rate of FT - FM - FI, where FI was a constant flow rate of indicator solution (EBT), and then mixed with the titrand. Downstream, the analytical signals of the mixed solution were monitored. First, a high-throughput photometric titration of a single analyte (Ca2+ or Mg2+) was examined by a feedback-based flow ratiometry coupled with a subsequent fixed triangular wave controlled flow ratiometry. Maximally 17 titrations could be done per minute with reasonable precision (RSD = ca. 1 %). Next, the algorithm of the former ratiometry was modified so that a photometric detector and a potentiometric detector (Ca2+-selective electrode) could detect the total concentration of both ions and the concentration of Ca2+, respectively, using EGTA as a titrant. The equivalence points of the photometry and the potentiometry were each estimated from the Vc values at the instant of the sensing of the corresponding equivalence signal in the course of upward and downward scans of Vc. Good throughput (ca. 31 s per determination) was attainable with allowable precision (RSD < 1.6 %).
    Download PDF (678K)
  • Original Paper
    Michio Zenki, Masako Kojima, Takashi Yokoyama
    2008 Volume 25 Issue 1 Pages 69-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    A single-line flow system, through which a reagent carrier stream is circulated, is proposed for the spectrophotometric determination of acidity (expressed as citric acid content) in fruit juices and soft drinks. The reagent carrier solution consists of pH indicator (Methyl Orange, MO) and sugar (sucrose) in an acetate buffer solution. The method is based on the acid-base neutralization detecting the color change of MO. The resulting solution, after passing through a flow through cell, returns to the reservoir and reused repeatedly. Sucrose is added in the reagent carrier solution to compensate both the differences in refractive index and viscosity between the reagent carrier solution and the sample solution, which make the sample injection directly without any dilution process. Several parameters were optimized, resulting in a simple, fast, and ready constructed acidity analyzer. Fruits juices and soft drinks could be analyzed without any prior chemical treatment.
    Download PDF (781K)
  • Original Paper
    Koji Oshita, Toshio Takayanagi, Mitsuko Oshima, Shoji Motomizu
    2008 Volume 25 Issue 1 Pages 73-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Cross-linked chitosan resins possessing serine moiety (serine-type chitosan resins) were synthesized for the collection of trace uranium and the separation of matrices in seawater prior to ICP-MS measurement. The serine moiety has a carboxyl group and an amino group at the β-carbon position of ethanol. The adsorption behavior of trace elements on two types of chitosan resin, coupled with the hydroxyl group of serine (type 1) and with the amino group of serine (type 2), was investigated by using a proposed column procedure. The serine-type chitosan resin (type 1) adsorbed U(VI) over wide pH regions from 2 – 9, and especially could collect U(VI) at acidic pH regions selectively by forming stable chelate with the amino group and the carboxyl group of the serine moiety introduced to chitosan. Further, the flow injection/ICP-MS system was developed for the determination of trace uranium in seawater using a small column packed with the resin. The proposed system could be applied to the uranium analysis.
    Download PDF (433K)
  • Original Paper
    Shintaro Takeda, Hiromi Yagi, Satoru Mizuguchi, Hitoshi Funahashi, Hir ...
    2008 Volume 25 Issue 1 Pages 77-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Chemical Sensors and detectors play important roles in FIA systems. We have developed a molecularly imprinted polymer based amperometric sensor, which allows the detection of trace concentrations of adenosine triphosphate (ATP), aiming at food safety applications. The sensor has a small carbon electrode covered with an overoxidized polypyrrole film imprinted with an ATP molecule. The sensor operated in the triple pulse amperometric mode and was characterized in both the batchwise and flow-injection measurements. We have detected trace levels of ATP down to 5 nM without employing any separate preconcentration techniques.
    Download PDF (499K)
  • Hiroshi Shiigi, Hiroaki Matsumoto, Itaru Ota, Tsutomu Nagaoka
    2008 Volume 25 Issue 1 Pages 81-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Our research goal is based on the acquisition of bio-information from the analysis of skin components by using a simple test. Controlling the total cholesterol level is important for preventing lifestyle-related diseases. Approximately 11% of the body’s cholesterol is present in the skin and is equal to the percentage found in the blood. Therefore, we focused on a simple and non-invasive method of measuring cholesterol by using a solvent to extract the skin component. The extracted solution was analyzed using high-performance liquid chromatography (HPLC) and a molecularly imprinted self-assembled monolayer (SAM) sensor. The molecularly imprinted SAM electrode had high responsiveness and sensitivity, which were attributed to its strong affinity toward hydrophobic cholesterol due to the presence of a long side chain and the complementary structure of the cavity. The subject with the highest skin cholesterol level showed higher blood cholesterol concentration, while the subject with the lowest skin cholesterol level showed the lowest blood cholesterol concentration. Since the coefficient of correlation of the non-invasive method using the SAM electrode and the invasive conventional method was 0.9408, it was concluded that the former method had great potential for practical use.
    Download PDF (411K)
  • Topics
    Masaki Takeuchi
    2008 Volume 25 Issue 1 Pages 85-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Download PDF (325K)
  • Report
    Hideji Tanaka
    2008 Volume 25 Issue 1 Pages 86-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Download PDF (1265K)
  • FIA Title
    Hideji Tanaka
    2008 Volume 25 Issue 1 Pages 90-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Download PDF (208K)
  • FIA Title
    Toshio Takayanagi
    2008 Volume 25 Issue 1 Pages 91-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Download PDF (314K)
  • Announcements
    2008 Volume 25 Issue 1 Pages 105-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Download PDF (137K)
  • Toshihiko Imato
    2008 Volume 25 Issue 1 Pages 135-
    Published: 2008
    Released: October 06, 2018
    JOURNALS FREE ACCESS
    Download PDF (136K)
feedback
Top