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Volume 1 (1960)
- Issue 4 Pages 357-
- Issue 3 Pages 261-
- Issue 2 Pages 129-
- Issue 1 Pages 1-
Volume 1, Issue 3
Displaying 1-10 of 10 articles from this issue
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Tsuneo YOSHIDA, Masayoshi MORI, Yasuharu NIMURA, Shinpachi TAKAGISHI, ...1960 Volume 1 Issue 3 Pages 261-274
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSThe application of ultrasound to the examination within the body furnishes one with a tactile information which would be otherwise impossible. Especially the application of ultrasonic Doppler method assures one of reliable data for valvular movements which bear an influential, physiological and clinical significance.
The aim of the present study was directed to the detection with ultrasonic Doppler method of the time of valvular movements in cases of mitral valvular disease. The findings obtained here are very likely to promise to afford fundamental understanding in interpreting various pathophysiological entities.View full abstractDownload PDF (8791K) -
Ichiro DOHI, Yutaka DOHI, Tsutomu TADA, Yahiro MITA, Ken YOSHIDA, Yasu ...1960 Volume 1 Issue 3 Pages 275-287
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSBy depressing the A-V conduction system with procain-amide, the retrograde impulse of the ventricular extrasystole was sometimes blocked or followed by a reciprocal beat. The relation between the coupling time and the kinds of extrasystoles was examined. The retrograde conduction time of the ventricular extrasystoles with reciprocal beats had negative correlation with the coupling time and the antegrade conduction time of the reciprocal beat. Similar relations were found in the experiments of the reversed reciprocal rhythm, although it was far more difficult to produce this arrhythmia under the sinus rhythm.View full abstractDownload PDF (5760K) -
Jugoro TAKEUCHI, Sigeru YAGI, Shosaku NAKAYAMA, Takao IKEDA, Eiichi UC ...1960 Volume 1 Issue 3 Pages 288-299
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSAn attempt has been made to investigate the changes in blood pressure and renal blood flow induced by electrical stimulation of the diencephalon of dogs and to elucidate the significance of diencephalon in the regulation of renal circulation. The stimulation of the medial and midline nuclei group in the thalamus and most of the hypothalamic and subthalamic nuclei resulted in an increase in the blood pressure and a decrease in the renal blood flow which was attributed to the renal vasoconstriction. The stimulation of a part of the ventral and lateral nuclei group in the thalamus, a part of the preoptic area and anterior and middle portion in the hypothalamus resulted in a fall in blood pressure associated with a decrease in renal blood flow and it was believed that the renal blood vessel induced practically no or very slight constriction. On stimulation of the geniculate bodies, the ventral and lateral nuclei group, there often occurred little or no change in circulatory responses. No obvious findings were obtained in this case which suggested the presence of renal vasodilator nerve in these areas.View full abstractDownload PDF (8490K) -
Eiichi KIMURA, Hiroshi HANNYA, Koji YAHATA, Kiyoto SATAKE1960 Volume 1 Issue 3 Pages 300-307
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSPreliminary clinical observations are presented on the hypotensive effect of KK-25-S (N-dimethylaminopropyl-4, 7-endoethylene-4, 7, 8, 3-tetrahydro-4, 7-ethanoisoindoline), a newly synthesized ganglionic blocking agent. A significant response was obtained in 12 of 25 hypertensive cases (48%) treated with KK-25-S alone. Addition of reserpine resulted in a more favorable response, 18 of 21 cases (86%) treated with the combined therapy showing satisfactory hypotensive effect without development of significant tolerance to KK-25-S. The incidence of side effects, especially of constipation and orthostatic hypotension was less than that with other available ganglionic blocking agents. The encouraging results obtained here warrant further investigation of this drug.View full abstractDownload PDF (4338K) -
Jugoro TAKEUCHI, Tadanao TAKEDA, Koji NAKAJIMA, Takao IKEDA, Eiichi UC ...1960 Volume 1 Issue 3 Pages 308-316
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSAntihypertensive effect of KK-25-S, a new potent ganglionic blocking agent, was evaluated in patients with moderate to severe essential hypertension. In 7 subjects, hypotensive responses after single oral dose were tested. Significant blood pressure reduction occurred within one or 2 hours after the administration of the drug and persisted for 4 hours or more. Thirty-two patients were treated with KK-25-S for periods of 2 to 29 weeks. Seven of 9 patients treated with KK-25-S alone failed to maintain significant hypotensive effect, whereas in 20 of 26 patients who received KK-25-S combined with other hypotensive drugs, significant blood pressure reduction was maintained throughout the treatment. Side-effects of the drug due to parasympathetic blockade were seen but readily controlled. Postural hypotension was relatively infrequent and slight in degree. Comparative studies on hypotensive potencies were made among different ganglionic blocking agents. It is concluded that KK-25-S is a potent hypotensive drug and is useful for the treatment of hypertension.View full abstractDownload PDF (6993K) -
Part I. Construction of the Electric FieldMitsumasa SATO1960 Volume 1 Issue 3 Pages 317-324
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSIn the present study an attempt was made to systematize and clarify the vector theory from a new point of view, by means of mathematics particularly of algebra.
In this part, the algebraic definition of vector which has been understood simply as a quantity with magnitude and direction, is introduced (Chapter 1), and the start of the arguments is shown after re-defining the “electric field” by means of the definition (Chapter 2). The old hypothesis of single dipole is abandoned. The law of distribution of potentials on the body surface is expressed here as the “vector space generaling nature of the potentials.” The meaning of the catchy expression ELECTROCARDIOGRAM IS VECTOR, which contains the essential of this part, is explained.View full abstractDownload PDF (6211K) -
Toyomi SANO, Iwao OGAWA1960 Volume 1 Issue 3 Pages 325-332
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSThe solid angle formula in the theory of electrocardiography seemed to be too bold to be acceptable even as a first approximation, especially in unipolar chest leads, since this formula holds primarily in an infinite homogeneous conductor while the exploring electrode is placed so close to the heart. Namely, at least the boundary of the precordial chest wall was felt necessary to be taken into consideration. Considering this as a semi-infinite homogeneous conductor with some other assumed conditions and applying the lead field concept, it was found that the solid angle formula still holds but with a different constant. This proof implies that in such a case just like in an infinite homogeneous conductor the potential at the exploring electrode concerns merely with the shape and position of the boundary of the excited cardiac regions, which lies in most instants much deeper than the actual positions of some of the excited parts. It is to be noted, however, that for the conventional limb leads we have nothing to conclude about the theoretical validity of the solid angle formula.View full abstractDownload PDF (5133K) -
Hiroshi WATANABE, Tsuguya SAKAMOTO, Zen'ichiro UOZUMI, Tohru KOBAYASHI ...1960 Volume 1 Issue 3 Pages 333-338
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSALTHOUGH a musical diastolic murmur in aortic regurgitation is relatively uncommon, it has such a characteristic that one can hardly forget if he hears it once. Many authors have already reported this type of murmur and in many times its genesis was proved to be luetic in origin. Rheumatic and bacterial etiology appeared to be rare in this case. Moreover, the latter case accompanied by an apical rumbling murmur due to relative mitral narrowing may be extremely uncommon, and no such report has been appeared as yet in the literature.
This report illustrates an instance with a diastolic musical murmur associated with an apical rumbling murmur in a patient with aortic regurgitation due to bacterial origin.View full abstractDownload PDF (3266K) -
Kunio MATSUDA, Toshio OZAWA, Hiroichi NIITANI, Masao IKEDA1960 Volume 1 Issue 3 Pages 339-347
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSEBSTEIN in 1866 described the first case of this entity, consisting essentially of congenital malformation of the tricuspid valve and displacement of the valve downward into the right ventricle. Yater and Shapiro in 1937 summarized this anomaly and thought that “it would appear impossible to make the diagnosis during life”. In 1950 Engle et al. analyzed the clinical aspects of this disease concluding that there were sufficient characteristic features to allow the clinical diagnosis. Reynolds in 1950 and Soloff et al. in 1951 reported the first cases diagnosed during life. With the widespread use of modern diagnostic methods, such as catheterization and angio-cardiography, resulting in better understanding of the clinical syndrome, a considerable number of reports on the clinically established diagnosis of this disease have appeared recently. In Japan, however, the present case represents the first instance of which the accurate diagnosis was ascertained in autopsy and was reported at the 2nd Kanto District Meeting of the Japan Circulation Academy in Sept., 1956.View full abstractDownload PDF (7116K) -
Ryozo OKADA, Kenichi HARUMI, Masuyo NOMURA, Satoru MURAO1960 Volume 1 Issue 3 Pages 348-356
Published: 1960
Released on J-STAGE: October 26, 2009
JOURNAL FREE ACCESSIN recent years, diffuse myocardial fibrosis has received much attention by its difficulty in making diagnosis and its diverse etiology although the causal relationship between myocardial fibrosis and disease of the coronary arteries has been well recognized in many cases. The anatomic changes in the coronary arteries, however, seemed not always to be proportional to the changes in the myocardium. Though the importance of the sclerosis in proximal coronary arteries has been recognized, yet, changes in the small arteries in the myocardium and their effect on the myocardial nutrition have received very little attention. We have seen a case of small artery type of coronary sclerosis with diffuse myocardial fibrosis which had a Family history indicating other members of the family had similar ailment.View full abstractDownload PDF (5329K)
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