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Volume 11 (1970)
- Issue 6 Pages 515-
- Issue 5 Pages 423-
- Issue 4 Pages 309-
- Issue 3 Pages 213-
- Issue 2 Pages 121-
- Issue 1 Pages 1-
Volume 11, Issue 6
Displaying 1-8 of 8 articles from this issue
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Hiroshi YAMAMOTO, Kikuo ARAKAWA1970 Volume 11 Issue 6 Pages 515-520
Published: 1970
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSA new stereostethoscope for both monaural and binaural auscultation was devised. Two channels from chest to ear pieces are separate in binaural use but interchangeable for monaural use by a simple 3 way cock set in between. In binaural use, one heart sound or murmur can be heard stereophonically, and more than 2 separate sounds can be heard simultaneously. Recognition of, or distinction of, the heart sounds or murmurs are thus made easy and help to contribute in diagnosing heart diseases more precisely. Respiratory auscultation can be done even more precisely and time savingly.View full abstractDownload PDF (766K) -
The Hemodynamic Effects of Digitalis on ExerciseLawrence GOULD, Mohammad ZAHIR, Mahmood SHARIFF, Ramiro DEGUIA, Mary D ...1970 Volume 11 Issue 6 Pages 521-532
Published: 1970
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSThirteen chronic alcoholic male patients with normal cardiovascular findings and minimal or no liver disease underwent right and left heart catheterizations. Cardiac pressures and cardiac outputs were obtained at rest and during exercise. An abnormal alteration in pressure or flow was demonstrated in 12 of the 13 subjects. Thirty minutes after the administration of 0.3mg. of ouabain a repeat exercise was performed. The abnormal rise in cardiac pressures observed in the pre-ouabain exercise state was now prevented. The cardiac index and stroke index fell in 6 patients while it rose in the other 7 patients. This varying response of the cardiac output is seen in normal subjects.
Digitalis, with its positive inotropic action on the left ventricle, can prevent the rise in the cardiac pressures. This may have clinical application in preventing congestive heart failure in the alcoholic patient undergoing surgery or any type of severe stress.View full abstractDownload PDF (646K) -
IV. Effect of Acute Aortic Constriction on Sodium ExcretionKazumichi NAKAMURA, Takashi KINOUCHI, Teizo ITO, Masahito NAGASAKA, Ma ...1970 Volume 11 Issue 6 Pages 533-540
Published: 1970
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSAfter the constant infusion of 100ml. of 10 per cent saline in 60min. in the dog, balloon was inflated in the aorta just above the renal arteries for 30min. When the decrease in GFR was mild (that is, 50 to 80 per cent of control value), urinary sodium output was not affected significantly demonstrating GFR was not an important factor in determining sodium excretion. However, when the reduction in GFR was more than 50 per cent, sodium output definitely decreased in the present experiment. During the aortic constriction potassium excretion was increased suggest-ing the augmentation of Na-K exchange in the renal tubules.View full abstractDownload PDF (364K) -
V. The Relative Importance of Plasma Na Concentration and GFR as the Determinants of Renal Na ExcretionMasahito NAGASAKA, Kazumichi NAKAMURA, Takashi KINOUCHI, Teizo ITO, Ma ...1970 Volume 11 Issue 6 Pages 541-549
Published: 1970
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSRenal Na excretion correlated well with the product of elevation in plasma Na concentration from original value and GFR, as was suspected from the kinetic model. This was found to be true in the control hypertonic saline diuresis and in the physiologic saline preloading experiment. However, in experiment with aortic constriction correlation was unsatisfactory.
Relative importance of elevation in plasma Na concentration and GFR was estimated by multiple regression analysis. Their importance was similar and original regression equation was verified in the control and the saline preloading experiment. However, in the aortic constriction experiment, while weight for elevation of plasma Na concentration remained unchanged, that for GFR was almost eliminated. This finding may be to explain the reported irrelevance of GFR to renal Na excretion during massive saline diuresis. It is postulated that manipulation of large artery system is the cause of this apparent irrelevance. Further, when GFR was reduced drastically by aortic constriction, renal Na excretion was again larger than was predicted by the regression equation with small coefficient for GFR.View full abstractDownload PDF (412K) -
Fumio TAKENAKA, Katsuhide NISHI, Matao SAKANASHI1970 Volume 11 Issue 6 Pages 550-558
Published: 1970
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSIn the lightly anesthetized cats, acute asphyxia alone did not produce any afferent discharges in the cardiac sympathetic nerve, while prolonged low ventilation provoked spontaneous afferent discharges and acute asphyxia combined with low ventilation increased the frequency of the impulses. Intravenous injection of epinephrine, acetylcholine and veratrine did not elicit afferent activities of the cardiac sympathetic nerve and also had no effect on the discharges caused by low ventilation. Intrapericardial injection of procaine abolished the afferent discharges in the nerve exerted by prolonged low ventilation. It seems that some metabolic factors produced by low ventilation would be responsible for the initiation of impulses at the afferent nerve endings of cardiac sympathetic innervation.View full abstractDownload PDF (953K) -
Toshiaki KIRIYAMA, Naoto ENDO, Masakazu OCHIAI, Hiroshi KUNISHIGE, Yos ...1970 Volume 11 Issue 6 Pages 559-572
Published: 1970
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSRespiratory variation in the intraatrial and atrioventricular conduction time and its mechanism were studied on 14 dogs under the following 3 conditions: (1) unanesthetized, (2) anesthetized with alpha-chloralose, and (3) anesthetized with pentobarbital sodium. Beautiful respiratory variation in the atrioventricular conduction time (shortening during inspiration and prolongation during expiration) was observed on both conditions (1) and (2), but nothing was observed in (3). No significant variation in the intra- and interatrial conduction time was observed under any condition. This "respiratory-conduction time response" (RCR) was almost in phase with the variation in the cardiac interval. Amplitude of the variation in RCR was 14.7±3.9msec. which corresponded to 3.8% of that of the variation in the cardiac interval. Augmentation of the RCR was observed on right atrial pacing with constant stimulus interval. It is concluded that RCR may result mainly from the waxing and waning of the efferent vagal activity to the atrioventricular node and in part from factor dependent upon heart rate change itself i.e. chronotropic dromotropism. It is supposed that the afferent pathway from the lung is not so important in the physiological state as the central origin in this phenomenon.View full abstractDownload PDF (2735K) -
Toshio AKIYAMA1970 Volume 11 Issue 6 Pages 573-581
Published: 1970
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSA case of 17-year-old negro highschool basketball player with serum hepatitis and labile T waves was reported with the pertinent clinical history, the laboratory data and the results of various procedures on an electrocardiogram.
The sharply inverted precordial T waves were temporary or labile, and the T waves were upright and normal in configuration after overnight fasting. Intravenous glucose was able to reduplicate their original T wave abnormality. The downward T waves, induced by the glucose, again became normal after intravenous administration of potassium. The inverted T waves were reverted immediately to normal on taking a single deep inspiration. In differentiating physiologic and organic T wave changes, it might be helpful to obtain an electrocardiogram on fasting state whenever a subject has a questionable T wave abnormality. It is felt that the abnormal appearance of T wave should not be the sole basis for diagnosing heart disease, but it should be correlated with careful clinical history, physical examination and pertinent laboratory data.
References on the juvenile pattern of electrocardiogram and the factors influencing on T wave were reviewed.View full abstractDownload PDF (2130K) -
Masaya SUGIURA, Terumi HAYASHI, Kunihiro UENO1970 Volume 11 Issue 6 Pages 582-585
Published: 1970
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSA case of partial absence of the right ventricular musculature was reported. The patient, 84-year-old female, had no cardiac symptoms or signs. The muscular defect of the right ventricle was first found at autopsy. It was 15×12mm. in size, located at the pulmonary conus and was histologically composed of endocardial and pericardial layers.View full abstractDownload PDF (1417K)
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