Japanese Heart Journal
Online ISSN : 1348-673X
Print ISSN : 0021-4868
ISSN-L : 0021-4868
16 巻, 2 号
選択された号の論文の12件中1~12を表示しています
  • Tsuguya SAKAMOTO, Mokuo MATSUHISA, Terumi HAYASHI, Hirofumi ICHIYASU
    1975 年 16 巻 2 号 p. 107-117
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    Pulmonary valve movement and the related acoustic phenomena were investigated using high speed strip-chart echo- and phonocardiographic recording. The opening of the pulmonary valve had no definite relationship to the acoustic phenomena, whereas the pulmonary ejection sound was closely related in time to the early systolic maximal opening of the valve. The concomitant pulmonary ejection systolic murmur faded away by the time of the mid-systolic semi-closure of the valve, where the tiny extrasound occurred in a half of cases. The pulmonary component of the second heart sound occurred after the valve closure, and the time lag maximally reached up to 50 msec. Pulmonary hypertension tended to minimize this delay, giving the so-called single loud second heart sound. Graham Steell murmur started with the pulmonary component of the second heart sound and reached up to the isometric contaction phase beyond the first heart sound.
  • Muhammad ILYAS, Masood Anwar PERACHA, Inayatur RAHMAN
    1975 年 16 巻 2 号 p. 118-121
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    A semi-automated sphygmomanometer Stanley B-200 has been compared with the clinical sphygmomanometer in 500 college boys by using a blind simultaneous method. Stanley B-200 has shown significantly higher systolic blood pressure (14.8mmHg, P<0.05) and diastolic blood pressure (3.8mmHg, P<0.05). This device also recorded 15 false positive systolic and 12 false negative diastolic results (P<0.05).
  • Tadashi KOIDE, Atsuo NAKANISHI, Iwao ITO, Hisakazu YASUDA, Yutaka TAKA ...
    1975 年 16 巻 2 号 p. 122-142
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    Seventy-four patients with rheumatic mitral stenosis were catheterized and hemodynamic and clinical significances of atrial fibrillation, pulmonary vascular resistance and left ventricular function were studied. These data were also compared to those in the 6 control cases.
    In addition to the correlation of mitral valve area to the functional classification of patients, significance of atrial fibrillation was also demonstrated. Patients with this arrhythmia had lower cardiac index than those with regular sinus rhythm by approximately 20%, throughout the range of mitral valve area observed. The lower average cardiac index was associated with a higher average left ventricular end-diastolic pressure in cases with atrial fibrillation than in cases without the arrhythmia, in the face of similar average heart rate and average mitral valve area.
    Average pulmonary vascular resistance correlated to the functional classification, but its systematic influence on the relation between mitral valve area and cardiac index was not observed.
    Abnormalities of left ventricular function were suggested frequently by various combinations of abnormal values in end-diastolic pressure, end-diastolic volume, ejection fraction, angiographically-measured circumferential fiber shortening velocity (Vcf), and pressure-derived maximal contractile element velocity (Vmax). Patients with enlarged left ventricle had significantly lower average cardiac index than those with normal ventricular size.
  • Shigetoshi CHIBA, Hiroshi ONO, Kazuhiko IWATSUKI
    1975 年 16 巻 2 号 p. 143-147
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    A constant pressure perfusion of the sinus node artery was performed in 10 in situ and in 3 isolated SA node preparations. The selective administration of apomorphine caused a negative chronotropic effect which was not blocked by treatment with atropine. The sinus deceleration was usually produced by apomorphine, 10-300μg, while sinus irregularity and finally atrioventricular nodal rhythm in the in situ preparation or sinus arrest in the isolated one resulted from doses above 1mg. In the in situ preparation at a higher dose from 300μg to 1mg, a slight sinus acceleration was occasionally induced following sinus deceleration. In this time, a fall in blood pressure was usually observed. This acceleration response to apomorphine was inhibited by propranolol.
    From these results, it is concluded that apomorphine induces direct depressive action on the SA node and, in extremely high doses, a slight sinus acceleration may be induced by reflex mechanism.
  • Akira ITO, Saul M. SCHANBERG
    1975 年 16 巻 2 号 p. 148-155
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    Effect of serotonin depletion in the rat brain on the sympathetic pressor response to occlusion of the common carotid arteries was examined along with the sequential transection of the brain stem. In rats with the brain serotonin depleted below 10% of control by p-chlorophenyl-alanine, the reflex pressor response significantly decreased, but the reflex sensitivity was unchanged in any transection regimen, suggesting the decrease originated in the associated hypertension. The infracollicular transection augmented the reflex reaction and sensitivity in both groups, and the medullospinal separation abolished the reflex. It is concluded that the brain serotonin would not be significantly involved in the central regulation of the sympathetic component of the carotid sinus reflex, and that the structure rostral to the midbrain could play an inhibitory role in the integrative regulation.
  • A Preliminary Note
    Motoomi NAKAMURA, Akio KUROIWA, Osamu NAKAGAKI, Hitonobu TOMOIKE, Yosh ...
    1975 年 16 巻 2 号 p. 156-161
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    Twenty spontaneously hypertensive rats (SHR) and 20 control rats were used for measurements of Rb86 uptake of various organs. Hemodynamic measurements and the heart weight to body weight ratio showed a significant and sustained hypertension and increased heart rate in SHR. Ratio of Rb86 uptake in the kidney, brain, liver, adrenal gland, pancreas, and spleen to that in RV was smaller in SHR than that in the control rats. The ratio of Rb86 uptake of inner layer to outer layer of LV, which represents distribution of blood flow to the endocardial layer and epicardial layer, was not different between SHR and the control rats. The fraction of regional flow in the outer and inner cortex, juxtamedulla, and medulla of the kidney was not different between SHR and the control. The present preliminary study may suggest that myocardial blood flow in SHR is greater than that in the control rats. The relationship between cardiac hypertrophy and myocardial flow was discussed.
  • Yasumi UCHIDA, Hideo UEDA
    1975 年 16 巻 2 号 p. 162-173
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    The blood flow through the anterior wall of the left ventricle has been studied during electrical stimulation of the left stellate ganglion of anesthetized dogs. The flow was continuously monitored by heated cross-thermocuple. Ganglion stimulation caused a significant increase in the flow through the outer half while producing relative ischemia of the inner half of the wall. Pretreatment with propranolol reduced regional differ-ence of flow changes. Significantly augmented non-uniform flow changes, however, were produced by ganglion stimulation during hypertension caused by aortic constriction or by methoxamine. The results indicate non-uniform blood flow distribution which can be produced by sympathetic nerve excitation.
  • Hitoshi TANIJIRI
    1975 年 16 巻 2 号 p. 174-188
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    The energy metabolism of cardiac hypertrophy in spontaneously hypertensive rats (SHR) was studied chronologically by histochemical and in part chemical methods. The activities of various enzymes, such as glucose-6-phosphate dehydrogenase (G6PDH), lactate dehydrogenase (LDH), isocitrate dehydrogenase, succinate dehydrogenase, Β-hydroxy-butylate dehydrogenase (Β-HBDH) and monoamine oxidase (MAO) in the cardiac muscle were determined histochemically. Β-HBDH activity was greatly increased in the stage of developing hypertension in SHR. LDH activity increased simultaneously with the rise of Β-HBDH activity. Moreover, MAO activity increased markedly in later stages when the blood pressure was already elevated in SHR. To confirm the histochemical findings of Β-HBDH activity, the mitochondrial fraction of cardiac muscle was subjected to chemical assay. The chemical findings of myo-cardial Β-HBDH in SHR corresponded well with the histochemical findings. The myocardial Β-HBDH activity in SHR increased markedly at the age of 5 to 9 weeks, while no or minimal activity was found in controls of the same age. No significant difference of Β-HBDH activity was observed between SHR and controls in the mitochondrial fraction from the diaphragm and liver. The increase of Β-HBDH activity in the cardiac muscle of SHR prior to the development of cardiac hypertrophy suggests that the metabolism of ketone bodies may play an important role in providing the energy necessary for the development of cardiac hypertrophy in SHR.
  • Report of Expert Committee of Pediatric Electrocardiogram, Division of Pediatric Cardiology, Japan Pediatric Society
    Masahiko Okuni
    1975 年 16 巻 2 号 p. 189-195
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    New electrocardiographic criteria for ventricular hypertrophy in chil-dren are offered. The new criteria have possible and definitive criteria for the consideration of borderline cases.
  • Tadanori SAITO, Mitsuo MATSUDA, Tetsu YAMAGUCHI, Tadashi MATSUZAKI, Sh ...
    1975 年 16 巻 2 号 p. 196-203
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    A case of systemic-pulmonary arteriovenous fistula is described. Chest trauma with multiple bone fractures 9 years prior to this admission was the suspected cause. Three years after the trauma, chest X-rays revealed abnormal vessels in the right lung. Eight years after the trauma, the patient developed congestive heart failure. This has been well controlled with digitalis and occasional diuretics.
  • Kazutoshi ISHIZAWA, Tsunetaro SAKURAI, Masao NAGAI, Kunihiko HIROSE, A ...
    1975 年 16 巻 2 号 p. 204-210
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    Pre-and post-operative vectorcardiograms (Frank system) and angio-cardiograms in a patient with Lutembacher's syndrome, were correlated. Preoperative vectorcardiogram showed the initial conduction delay, complete RBBB, increased QRS voltage, and open QRS loop, while left ventriculography and left atriography demonstrated the markedly posteriorly dislocated left ventricular major axis surrounded by the huge right ventricle and right atrium. Two months after operation, when the left ventricular major axis shifted from abnormally posteriorly directed to left and inferiorly, with the decreased right-sided heart chambers, the initial conduction delay disappeared with decreased QRS voltage. As these vectorcardiographic and angiocardiographic changes at the postoperative stage were parallel, we concluded that the initial conduction delay was a representation of" the pseudo-W-P-W syndrome" and due to the abnormally posteriorly dislocated left ventricular apex and the delayed excitation of the right ventricular free wall caused by the huge dilatation.
  • The Discussion about the Frequent Combination of the Cardiac Malformation, and the Observation at the Early Non-Cyanotic Period of Fallot's Tetralogy
    Zenshiro ONOUCHI, Takuji OOTSUKA, Eisuke OTABE, Hiroaki SASAGAWA, Yo T ...
    1975 年 16 巻 2 号 p. 211-220
    発行日: 1975年
    公開日: 2008/12/09
    ジャーナル フリー
    Even in the severe tetralogy of Fallot the performance of right ventricle is maintained normally without loaded pattern in ECG compensated by the blood flow derived through the ductus arteriosus at early neonatal period.
    Thereafter, stenotic murmur and reversed shunt appear, because the degree of right ventricular stenosis presumably increases gradually and right ventricular resistance11) become higher than systemic one.
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