巻号一覧
19 巻 (1978)
- 6 号 p. 829-
- 5 号 p. 675-
- 4 号 p. 455-
- 3 号 p. 315-
- 2 号 p. 175-
- 1 号 p. 1-
19 巻, 3 号
選択された号の論文の15件中1～15を表示しています
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Masaya TAKEUCHI, Naoki HAYASHI, Toshikatsu SADA1978 年 19 巻 3 号 p. 315-323
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーBy using an analogue computer with the X, Y and Z components of Frank's lead system as inputs, spatial velocity electrocardiograms (SVECG, SV), and spatial magnitude electrocardiograms (SMECG, SM) were recorded. At the same time, utilizing a direct writing vectorcardiograph and a X-Y plotter, a correlation curve between SVECG and SMECG was traced. Thirty normal human subjects, 21 patients suffering from hypertension without cardiac involvement and 70 cases of ischemic heart disease (IHD), such as myocardial infarction, angina pectoris, and asymptomatic IHD were studied in a recumbent position before and after Mster's two-step test.
The SMECG of QRS of the hypertensive patients was significantly greater both before and after exericise than that of the normal group, while that of the IHD group showed a significance only after the exercise. If the peaks of QRS and T of SVECG are called ρ1, ρ2, τ1, and τ2in their respective order, the ρ2 after exercise, τ1 before and after ex-ercise, and τ2 before exercise are significantly elevated in the hypertensive patients. τ2 showed a significant increase after exercise in each group studied, while τ2 in the normal and hypertensive groups declined noticeably.
SV and SM showed good positive correlation, but the correlation coefficient was poor in the IHD group and worsened after exercise. In the IHD patients, the positive group of the two-step test showed significantly poorer correlation than the negative group at ρ1. This indicates that SV is not determined by SM alone.抄録全体を表示PDF形式でダウンロード (449K) -
Isao SAKASHITA, Shin-ichi OHTANI, Chiharu NAKAMURA, Masahiko WASHIO1978 年 19 巻 3 号 p. 324-331
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーThromboembolic complication was correlated with the methods of anticoagulant therapy used in the patients with Starr-Edwards non cloth-covered or cloth-covered ball valve.
A new anticoagulant therapy combining Bucolome with Warfarin has been used for the patients who were unable to be maintained in a suitable range of thrombotest Owren with Warfarin alone. The results obtained in this new therapy showed that the incidence of thromboembolism was reduced to 0.02 per patient year or less in the patients with Starr-Edwards ball valve as well as Bjork-Shiley tilting disc valve.抄録全体を表示PDF形式でダウンロード (848K) -
Shigenori MOROOKA, Akihito KATO, Satoru MURAO, Hirofumi OHSUZU1978 年 19 巻 3 号 p. 332-345
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーLong term clinical courses of a patient and her family with idio-pathic cardiomyopathy and WPW syndrome were described. The mother and her brother (the first generation) had died of heart disease, and 1 sibling had also died suddenly of heart disease when the study began. Seven out of the 8 siblings (the second generation) were followed for 17 years from 1958 to 1976. The 4 siblings had both typical or atypical WPW syndrome and cardiomegaly in 1958, 2 of them died suddenly and unexpectedly, 1 of them died of congestive heart failure, and I of them did not have any complaint during the period. One was normal in 1958 but developed cardiomegaly and atypical WPW syndrome in 1976. The other 2 were normal in both 1958 and 1976. The 2 children of the second sibling (the third generation) were followed simultaneously for 15 years. Both had WPW syndrome without cardiomegaly.
It was suggested that a late onset of the disease could occur in the family with young onset, that the clinical course might become different mainly by sudden cardiac death which occurred only in the members with abnormal findings, and that WPW syndrome and cardiomegaly could be inherited or occur together in the same generation but separately in the different generation.抄録全体を表示PDF形式でダウンロード (6823K) -
A Basic Reorientation in the Approach to the Definition of Congenital Heart DefectsJami G. SHAKIBI, Iraj ARYANPUR, Iraj NAZARIAN, Bijan SIASSI1978 年 19 巻 3 号 p. 346-357
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーA heart specimen is presented which showed a rare combination of atrioventricular valve atresia with single ventricle, truncus arteriosus communis with an anteriorly placed trunk, ie transposition. Because of the problems involved in the classification of this heart, the types of single ventricle are revised with particular attention to the rare cases of atrioventricular valve atresia and single ventricle reported in the literature. Also the rare type of truncus arteriosus communis with truncoatrioventricular valve discontinuity is excluded from the so-called transposition complexes, and properly classified as a form of truncus. The literal meaning of transposition is stressed and it is urged to approach congenital heart defects in a purely anatomic sense with definition of each segment as accurately as possible. Thus the present confusion in terminology and further plethora of new terms are avoided.抄録全体を表示PDF形式でダウンロード (1784K) -
A Heretofore Undescribed AssociationP. CHOPRA, V. SINGHAL, N.C. NAYAK1978 年 19 巻 3 号 p. 358-365
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーAn interesting association between aortoarteritis syndrome (Takayasu's arteriopathy) and congestive cardiomyopathy has been described for the first time. The severe congestive heart failure in 3 out of 4 cases reported here was not associated with hypertension. Morphologic features of the heart in all cases were characteristic of congestive cardiomyopathy, while in the aorta and its branches, anatomical changes were those of aortoarteritis. An etiopathogenic relationship between the 2 conditions is likely to be present in these cases.抄録全体を表示PDF形式でダウンロード (1163K) -
Bahram MOEZZI, Vahab FATOURECHI, Roholah KHOZAIN, Bahraim ESLAMI1978 年 19 巻 3 号 p. 366-370
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーThe effect of 1Gm of penicillamine (pen) on serum digoxin levels (SDLs) of 3 groups of patients (Pts) on maintenance digoxin therapy was studied. Each group served as its own control. Group I (10pts) had serum digoxin measurements (SDMs) 2, 4, and 6 hours (hrs) after receiving their daily oral doses of digoxin. The next day SDMs were made similarly following 1Gm of pen 2hrs after administration of digoxin. In all pts the SDLs were significantly lower 2, 4, and 6hrs after receiving pen (1.86±0.25 VS 1.62±0.22, 1.80±0.17 VS 1.44±0.26, 1.87±0.27 VS 1.14±0.24ng/ml, mean±SD with respective p values<0.025, <0.005 and <0.001).
In order to exclude the interference of pen on digoxin absorption, Group II (13pts) had SDMs 22hrs after their last oral doses of digoxin before and 6hrs after receiving 1Gm of pen. In this group SDLs were also significantly reduced (1.50±0.48 VS 1.16±0.51ng⁄ml, mean±SD, <0.05).
Group III (10pts) received maintenance intravenous digoxin for 5 days prior to SDM. In this group also marked reduction of SDM was observed 4 and 6hrs following 1Gm of pen (1.36±0.50 VS 1.04±0.40, 1.46±0.69 VS 0.50±0.64ng⁄ml, mean±SD with p values of <0.001 and <0.005, respectively). It can be concluded that oral penicillamine reduces SDL significantly in digitalized pts irrespective of the route of digoxin administration and may be of significant value in management of digitalis toxicity.抄録全体を表示PDF形式でダウンロード (303K) -
Hisayoshi FUJIWARA, Chuichi KAWAI, Yoshihiro HAMASHIMA1978 年 19 巻 3 号 p. 371-375
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーPathological findings of coronary heart disease were compared between patients with lung cancer and with cancer in the other organs in male subjects over 55 years of age.
Myocardial infarction was found in 13 of 58 subjects with lung cancer and in 5 of 79 subjects with cancer in the other organs (P<0.02). The subjects with severe stenoses of major coronary arteries were more frequent in lung cancer group (13 of 58) than in cancer group in the other organs (4 of 79 subjects: p<0.01). In 12 of 13 subjedcts with lung cancer and myocardial infarction the infarction seemed to occur due to coronary stenosis.
The subjects with lung cancer had significant increase of heart weight in comparison with subjects with cancer in the other organs.抄録全体を表示PDF形式でダウンロード (268K) -
Takashi HANEDA, William GANZ, Michael H. BURNAM, Joseph KATZ1978 年 19 巻 3 号 p. 376-382
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーThis investigation was designed to explore the metabolic, hemodynamic, and electrocardiographic effects of glucose-insulin-potassium (GIK) solution in a model of segmental myocardial ischemia with significant but incomplete restriction of coronary blood flow. An open-chest anesthetized canine model was utilized including 11 GIK and 6 saline control experiments. The anterior descending coronary artery (LAD) was partially occluded causing an average 71% reduction in its blood flow. Thirty min following occlusion GIK or saline was infused for 30min at 3ml/min into a femoral vein. Statistically significant effects of GIK included: increased glucose uptake by the ischemic myocardium, reduced arterial free fatty acid (FFA) concentration, reduced myocardial FFA uptake, decreased coronary arterio-venous oxygen content difference, increased myocardial lactate extraction, decreased myocardial potassium egress, and reduced epicardial ST segment elevation. Heart rate, aortic and left ventricular end-diastolic pressures, and developed force in the ischemic area were unchanged. The results indicate a potentially favorable effect of GIK on the metabolism of the ischemic myocardium which may be due to the shift of substrate utilization from free fatty acids to glucose.抄録全体を表示PDF形式でダウンロード (389K) -
K. PRASAD, M.M. GUPTA, B.L. GRAHAM1978 年 19 巻 3 号 p. 383-395
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーThe present paper presents a simple and unambiguous computerassisted method for the detection of cardiac disorders by processing the electrocardiogram. A new technique "Phase Invariant Signature Algorithm (PISA)", has been described, which is useful in the detection of cardiac abnormalities by investigating certain statistical properties of the measured waveform of ECG in a "phase-locked" fashion. This method of detection of abnormalities in the heart was used in the changes in the hypoxic action potential and in the ECG due to ionic changes and ischemia in the heart of cats and dogs. The signature of the normal ECG or action potential was straight-line. Any change in the waveform of ECG or action potential was detected as spikes in the signature. This method of detection of cardiac abnormalities does not require a priori reference to any standard ECG. The results indicate that this new method is capable of detecting cardiac disorders at an early stage and hence a higher sensitivity than the presently available type of ECG analysis. This method is in the developmental stage and further studies are being carried out.抄録全体を表示PDF形式でダウンロード (677K) -
Mitsuyoshi NAKASHIMA, Hisakuni HASHIMOTO, Mitsutaka KANAMARU, Teruo NA ...1978 年 19 巻 3 号 p. 396-408
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーDuring myocardial ischemia produced in 43 dogs by occlusion of left coronary artery, electrical alternans developed in 34 experiments. The most common was alternans of ST-T complex.
Surface and intracellular electrograms were recorded simultaneously from contiguous sites in the ischemic area. The alternans of ST-T complex in the surface electrogram corresponded to that of the rate of repolarization of the membrane action potential. The development of this alternans is localized in 2 relatively small area and transient. This may be the reason why electrical alternans of ST-T is clinically rare.
A clinical case showing electrocardiographic changes of electrical alternans of ST-T complex without any change in the QRS complex is reported. Myocardial infarction and hypokalemia is considered as a cause of the alternans.
The present results support the hypothesis that the mechanism of electrical alternans will be an alternation of the rate and extent of the ions transported across the myocardial cell membrane.抄録全体を表示PDF形式でダウンロード (783K) -
Shigetoshi CHIBA, Miyoharu KOBAYASHI, Yasuyuki FURUKAWA1978 年 19 巻 3 号 p. 409-414
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーUsing 10 isolated, blood-perfused canine atrial, and ventricular preparations, the effects of d- and l-verapamil on SA nodal pacemaker activity and contractility were investigated. l-verapamil and d-verapamil produced dose-related negative chronotropic and inotropic effects in all experiments. l-verapamil was approximately 10 times more potent than d-verapamil both in inotropism and chronotropism. Negative inotropism of either d- or l-verapamil can be reversed by injection of calcium chloride. Not only d-verapamil but also l-verapamil produced a stronger suppression at higher frequencies in both atrial and ventricular muscles.抄録全体を表示PDF形式でダウンロード (294K) -
Kay MILLAR, Mary Jo BURGESS, Kenichi HARUMI, Masahiro MURAYAMA, J.A. A ...1978 年 19 巻 3 号 p. 415-425
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーThe sequence of localized changes in ventricular repolarization time during and after temporary coronary artery occlusion was studied in 10 open chest dogs. Immediately after the onset of coronary occlusion functional refractory periods (FRPs) prolonged slightly in the ischemic area, then shortened with continued occlusion. Within the first minute following release of occlusion, FRPs underwent a further brief decrease in duration. By varying the period of occlusion from 11/2 to 61/2min, evidence was obtained that the post-release shortening of FRPs was temporally related to release of the clamp and not to the onset of occlusion. Ventricular fibrillation occurred in 2 dogs, in each instance soon after release of the coronary artery occlusion. The possible relationship of these experimental FRP changes to waveform abnormalities and arrhythmias in ischemic heart disease is discussed.抄録全体を表示PDF形式でダウンロード (1230K) -
W.J. DEMPSTER1978 年 19 巻 3 号 p. 426-433
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーPDF形式でダウンロード (1830K) -
Shigeru KAWAGOE, Keiichi HASHIMOTO, Hirokazu HAYAKAWA, Eiichi KIMURA1978 年 19 巻 3 号 p. 434-438
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーA case is reported in which atrial dissociation occurred after oral isoproterenol administration to increase the heart rate in the presence of complete atrioventricular block. Two types of P wave, one with small upward deflection and the other with deep downward spike-like deflection, were present. The latter wave appeared at a high rate of 300/min, suggesting the existence of atrial flutter in the left atrium alone.抄録全体を表示PDF形式でダウンロード (1382K) -
Review of the World Literature and Guidelines for Surgical RepairJami G. SHAKIBI, Houshang RASTAN, Iraj NAZARIAN, Mansoureh PAYDAR, Ira ...1978 年 19 巻 3 号 p. 439-451
発行日: 1978年
公開日: 2008/12/09
ジャーナル フリーA 10-month-old boy is presented who had isolated unilateral absence of the right pulmonary artery. He suffered from hemoptysis and severe congestive heart failure. The patient underwent prosthetic anastomosis of the right to the main pulmonary artery. Although the hemodynamic response was favorable, his oxygenation did not improve due to diffuse pulmonary arteriovenous fistulae of the affected lung. The patient succumbed 3 months after operation due to massive uncontrollable hemoptysis from the right lung.
Isolated unilateral absence of the pulmonary artery is a rare lesion. In our review of the world literature as of November 1976, 47 cases (including this report) of the unilateral absence of the pulmonary artery have been reported. Of these 25.5% had pulmonary hypertension and only 4 cases underwent successful repair of the lesion. Though repair of this defect can be carried out, the result may not be always gratifying. Our experience with this case has led us to consider a lung biopsy before proceeding to the surgical repair of the lesion. If the affected lung shows arteriovenous abnormalities the operation should not be recommended.抄録全体を表示PDF形式でダウンロード (2535K)
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