All issues
Successor
Volume 27, Issue 1
Displaying 1-15 of 15 articles from this issue
- |<
- <
- 1
- >
- >|
-
Nail CAGLAR, Haruo ARAKI, Yoshiyuki NAGATA, Ryuichi HISANO, Takaya FUK ...1986 Volume 27 Issue 1 Pages 1-9
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSWe performed equilibrium radionuclide ventriculography in 12 patients with idiopathic dilated cardiomyopathy, 11 patients with ischemic cardiomyopathy and 11 normal subjects to determine whether measurements of right ventricular function could be used to distinguish dilated cardiomyopathy from ischemic cardiomyopathy. The left ventricular ejection fraction in patients with dilated cardiomyopathy (26±8%, mean±SD) or ischemic cardiomyopathy (32±5%) was significantly lower than in normals (69±6%, p<0.001). The right ventricular ejection fraction (RVEF) in normals was 57±7%. RVEF was decreased in 11 of 12 patients with dilated cardiomyopathy and the mean value (32±10%) was significantly lower than that in patients with ischemic cardiomyopathy (56±7%, p<0.001), none of whom had decreased RVEF. Our data show that right ventricular dysfunction commonly exists in patients with dilated cardiomyopathy but not in patients with ischemic cardiomyopathy. This finding may be useful in the differentiation between dilated and ischemic cardiomyopathy.View full abstractDownload PDF (504K) -
Boonchob PONGPANICH, Sawanee ISARAPRASART1986 Volume 27 Issue 1 Pages 11-15
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSFifty infants and children with a diagnosis of congestive cardiomyopathy were reviewed at the Department of Pediatrics, Rama-thibodi Hospital. These patients were followed for an average of 2.9 years. Congestive heart failure was present in 82.6% of the cases. Of these patients, 43% died, 82% within the first year of their illness. Residual heart disease continues in 30%, while 27% made a complete recovery.
Factors that were highly predictive of the clinical course are age, cardiothoracic ratio of initial and subsequent chest X rays and the initial response to treatment. Infants less than 1 year old had a poor prognosis. The higher the cardiothoracic ratio on the initial and subsequent examinations and the poorer the response to medical treatment, the poorer the prognosis.View full abstractDownload PDF (225K) -
Yoshiaki TAKAYAMA, Akira SEKI, Kouji IMATAKA, Jun FUJII1986 Volume 27 Issue 1 Pages 17-23
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSExercise tests occasionally induce a QRS axis shift. Reviewing single Master's two-step test electrocardiograms of 1810 patients, we examined the incidence of the QRS axis shift and the relations of the QRS axis shifts to ischemic heart disease. The QRS axis shift was 30 degrees or more to the right in 38 (2.1%), 15 to 29 degrees to the right in 304 (16.8%), less than 15 degrees to the right or to the left in 1375 (75.9%), 15 to 29 degrees to the left in 81 (4.5%), and 30 degrees or more to the left in 12 patients (0.7%). The frequency of positive Master's tests and clinical ischemic heart disease were both significantly greater in the patients with QRS axis shifts of 30 degrees or more to the right (15.8% and 26.3%, respectively) and the patients with those of 30 degrees or more to the left (33.3% and 50.0%, respectively) than in the patients with shifts less than 15 degrees (6.5% and 8.5%, respectively). These results indicate that the exercise-induced QRS axis shift is a useful clue for the diagnosis of ischemic heart disease.View full abstractDownload PDF (391K) -
Betau HWANG, Laura MENG, Ching-Yuang LIN, Hey-Chi HSU1986 Volume 27 Issue 1 Pages 25-34
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSFive cases of infant glycogen storage disease of the heart are reported. Their ages ranged from 2 to 7 months. They all presented with generalized hypotonia and respiratory tract infections. Four of the diagnosis were proven by skeletal muscle biopsy and enzymatic assay of alpha-1, 4-glucosidase. All 5 infants had clinical signs of cardiac failure, cardiomegaly shown by chest X-ray, short PR intervals, severe left or bi-ventricular hypertrophy shown on electrocardiograms, increased thickness of the right and left ventricular walls and interventricular septum both on M-mode and two-dimensional echocardiograms and angiocardiograms. Four of them died during the follow-up period with a mean age at death of 7.5 months.View full abstractDownload PDF (2444K) -
The Effect of Commissurotomy and Valve Replacement on Left Ventricular Systolic FunctionShigeru KAZAMA, Katsuhiko NISHIGUCHI, Kazuhiko SONODA, Hidehiro NAKAJI ...1986 Volume 27 Issue 1 Pages 35-42
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSPreoperative and postoperative left ventricular cineangiograms of 26 patients with mitral stenosis (MS) were analyzed to calculate left ventricular end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF) and systolic regional wall motion. Nine patients underwent commissurotomy (OMC group) and 17 patients underwent mitral valve replacement (MVR group).
In both groups, postoperative EDV, SV and EF tended to increase, while ESV remained unchanged. In the OMC group, systolic wall motion of the left ventricle was found to be improved postoperatively, whereas systolic wall motion in the MVR group was found to be impaired postoperatively. The latter finding was assumed to be due to excision of the papillary muscles and chordae tendineae. Preservation of these structures is likely to be important for better postoperative functional recovery of the left ventricle.View full abstractDownload PDF (408K) -
Komei SAITO, Yutaka FURUTA, Hiroshi SANO, Takehiro OMATSU, Junji YAMAN ...1986 Volume 27 Issue 1 Pages 43-53
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSRed cell membrane sodium permeability was studied in 41 untreated patients with essential hypertension (20 borderline hypertensives and 21 established hypertensives) and 21 age matched normotensive subjects by means of the measurement of unidirectional passive influx of 22Na+ into ouabain-treated erythrocytes. The mean value (±SD) of 22Na+ influx was greater in the hypertensives than in the normotensives (0.183±0.047 vs 0.152±0.047 mmol/l•cells/hr, respectively, p<0.02). Among the patients with essential hypertension, the borderline hypertensives demonstrated a higher 22Na+ influx than the established hypertensives (0.207±0.043 vs 0.160±0.038 mmol/1•cells/hr, respectively, p<0.001), and 22Na+ influx positively correlated with plasma renin activity (r=0.44, p<0.005). In 16 of 20 borderline hypertensives, 5 year blood pressure changes were examined retrospectively, and a positive correlation was observed between mean blood pressure increase and 22Na+ influx value in these subjects (r=0.64, p<0.01). These results suggest that passive sodium influx may be altered in the course of the development of hypertension in relation to the changes in blood pressure level and that enhanced sodium permeability may be a characteristic of the early stage of essential hypertension.View full abstractDownload PDF (623K) -
Keiji UEDA, Iwao KUWAJIMA, Mototaka MURAKAMI, Hiromi YOSHIDA1986 Volume 27 Issue 1 Pages 55-70
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSThe antihypertensive effect and safety of long-term therapy with nifedipine were evaluated in 132 hypertensive patients, including 100 aged patients who received nifedipine alone or with other antihypertensive agents for a mean duration of 28.6 months.
A prompt hypotensive effect was observed 1 month after the initiation of nifedipine therapy. The hypotensive effect persisted for the entire follow-up period and was related to the pretreatment mean blood pressure level. Late drug tolerance was not observed.
Dizziness, facial flushing and other unpleasant sensations were observed in 7.5% and ankle edema in 9.8% of the patients. The therapy did not significantly influence serum creatinine levels. Hypotension and side effects were the cause of discontinuation in 10.6% and 4.5% of patients, respectively.
We conclude that long-term antihypertensive therapy with nifedipine is both effective and safe, not only in adult patients but also in the high-risk aged patient.View full abstractDownload PDF (902K) -
Katsusuke YANO, Motonobu HAYANO, Yoriaki MATSUMOTO, Takao MITSUOKA, Fu ...1986 Volume 27 Issue 1 Pages 71-81
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSSix-hydroxydopamine (6OHDA) was injected directly into the subepicardium of the sinus node area in an attempt to damage sympathetic nerve terminals in the sinus node. The changes in sinus node function were observed for 4 weeks. The predominant rhythm was of sinus origin throughout the observation period. The sinus rate progressively decreased from 145.1±14.2 to 76.2±12.1 beats/min during the first week after injection of 6OHDA. The sinus rate remained at this level for 2 weeks, followed by a gradual increase to 89.3±18.2 beats/min 4 weeks after injection of 6OHDA. These sinus rates were only significantly different from control dogs through the 14th postoperative day. The sinus rate was considerably increased by intravenous atropine injections 5 to 7 days after the injection of 6OHDA into the sinus node area. The sinus node recovery time was much longer in dogs with an injection of 6OHDA than that in the control dogs throughout the observed period.
These results suggest that elimination of the sympathetic influences on the sinus node can be achieved by direct injection of 6OHDA into the sinus node area in the dog, and that sinus node function can be depressed by decreasing sympathetic tone alone, in the absence of an intrinsic dysfunction of the sinus node.View full abstractDownload PDF (650K) -
Shin SUZUKI, Masao KOBAYASHI, Kunitake HASHIBA1986 Volume 27 Issue 1 Pages 83-93
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSRenal prostaglandins and kallikrein are considered to play an important role in the control of renin release. Recently, we have shown that aprotinin, a kallikrein inhibitor, inhibits the stimulation of plasma renin activity (PRA) by either furosemide or a low sodium diet. However, the mechanisms of action of kallikrein are unknown. Since kallikrein may stimulate bradykinin and prostaglandin production, the present study examines the relationship of renal kallikrein and renal prostaglandins in the control of renin release. Furosemide and a low sodium diet stimulated PRA, urinary kallikrein excretion and urinary prostaglandin E2 excretion. Aprotinin and indomethacin inhibited both furosemide and low sodium diet stimulation of PRA. When maximum doses of both aprotinin and indomethacin were given, PRA was more strongly suppressed than by indomethacin alone. The stimulation of urinary kallikrein excretion by furosemide and by a low sodium diet was not inhibited by indomethacin. These results suggest that both renal kallikrein and prostaglandins play an important role in the control of renin release under sodium depletion. Renal kallikrein may also have a direct action on the kidney to release renin.View full abstractDownload PDF (486K) -
Masanobu TAKATA, Xunfan ZHANG, Tsuneaki SUGIMOTO, Kiyoshi IKEDA, Fumih ...1986 Volume 27 Issue 1 Pages 95-106
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSThe antihypertensive effects of intravenous injection of ketan-serin, a 5-HT2 receptor antagonist, were assessed in conscious rabbits. In intact rabbits, ketanserin lowered blood pressure in a dose-dependent manner. The antihypertensive effects of ketanserin were also observed in rabbits with two-kidney, one clip (2K1C) hypertension and with one-kidney, one clip (1K1C) hypertension. The effect was more marked in the 1K1C rabbits with low plasma renin activity (PRA) and high plasma norepinephrine (PNE) than in 2K1C rabbits with high PRA and normal PNE. The heart rate was not changed. Ketanserin suppressed the pressor response to exogenous norepinephrine (0.6μg/Kg) 15, 30 and 45 min after the injection of ketanserin (1mg/Kg). It also suppressed the pressor response to phenylephrine (3μg/Kg) 15 min after the injection, but it did not suppress the pressor response to angiotensin II (0.15μg/Kg). In order to investigate baroreceptor function, balloons were placed around the abdominal aorta and the inferior vena cava and inflated alternately. Thus, the mean arterial pressure vs heart period-logistic curve was obtained under steady-state conditions. There were no changes after the drug administration in the range of heart period and the gain (the slope at midpoint of the curve). These results suggest that the inhibition of pressor response of norepinephrine has effects in addition to a direct vasodilatory action and that an alteration of baroreceptor function is not involved in the antihypertensive effects of ketanserin.View full abstractDownload PDF (587K) -
Yasuhide NAKASHIMA, Takashi FUJIHIRA, Yasunori FUKUCHI, Nobuyoshi ISHI ...1986 Volume 27 Issue 1 Pages 107-116
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSA 42 year old man with variant angina occasionally associated with syncopal attacks died of acute myocardial infarction 17 months after the onset of angina. Prior to the onset of variant angina, he had Raynaud's phenomenon of the tongue for 2 years. Both Valsalva maneuver and hyperventilation could repeatedly provoke chest pain and ST segment elevation in leads II, III and aVF. The infusion of prostaglandin E1 at a rate of 0.05μg/kg/min, was able to prevent the attack of variant angina induced by these maneuvers.
Although coronary angiography performed 15 months prior to death revealed no organic lesions except for complete spastic occlusion at segment 1 following intravenous ergonovine, autopsy revealed marked intimal proliferation and accumulation of abundant glycosaminoglycans in three coronary vessels, as well as in small and muscular arteries of other organs.
This suggests that a rapid systemic progression of narrowing due to proliferation of the intima might occur in some cases of variant angina.View full abstractDownload PDF (2171K) -
A Previously Undescribed Association with Cor Triatriatum and Double Right Ventricular ChamberJorge R. BÜCHLER, Manuel N. CANO1986 Volume 27 Issue 1 Pages 117-122
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSDouble-outlet right ventricle with viscero-atrial situs solitus, right-sided right ventricle and left-sided aorta is an unusual finding. In the present case it was found in association with a cor triatriatum and a double right ventricular chamber, a condition which has not been described previously.
Dextrocardia, subaortic ventricular septal defect, atrial septal defect ostium secundum type and absence of pulmonary and aortic stenosis at any level were also noted.View full abstractDownload PDF (1282K) -
George KOUVARAS, George BACOULAS1986 Volume 27 Issue 1 Pages 123-128
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSFour cases with cerebral ischaemic events and mitral valve prolapse are described. Full investigations failed to reveal any other potential cause for these cerebral events.View full abstractDownload PDF (1013K) -
Shinichi NUNODA, Junichiro MIFUNE, Susumu ONO, Akira NAKAYAMA, Senshu ...1986 Volume 27 Issue 1 Pages 129-135
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSWe report the case of a 55-year-old woman with mixed connective tissue disease (MCTD), who developed perimyocarditis associated with massive pericardial effusion. The diagnosis of MCTD was based on clinical and serological findings. We confirmed myocarditis by right ventricular endomyocardial biopsy. The pericardial effusion gradually disappeared after the administration of prednisolone. Although there have been several reports of cardiac disease in adult MCTD, few cases of adult MCTD having perimyocarditis associated with massive pericardial effusion have been reported.View full abstractDownload PDF (1823K) -
Motomu TSUJI, Toshio NAKATANI, Tsunenori NOJIRI, Hideki NISHIO, Hiroki ...1986 Volume 27 Issue 1 Pages 137-143
Published: 1986
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSThe case of a 61 year old woman with Sjögren's syndrome with aortic and mitral stenosis is reported. She suffered from rheumatic fever at a young age. Physical and echocardiographic examinations showed findings of mitral and aortic valve stenosis. In addition, she had experienced xerostomia, a gritty sensation in the eyes and Raynaud's phenomenon. Blood examination showed hypergammaglobulinemia, positive rheumatoid factor, antinuclear and anti-Ro (SS-A) antibodies. The diagnosis of Sjögren's syndrome was confirmed by sialography and biopsy of the labial salivary gland. The combination of valvular disease and Sjögren's syndrome is rare and the etiological correlation is discussed.View full abstractDownload PDF (1468K)
- |<
- <
- 1
- >
- >|