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Volume 7 (1966)
- Issue 6 Pages 513-
- Issue 5 Pages 415-
- Issue 4 Pages 305-
- Issue 3 Pages 201-
- Issue 2 Pages 101-
- Issue 1 Pages 1-
Volume 7, Issue 5
Displaying 1-10 of 10 articles from this issue
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Takashi NAKAMURA1966 Volume 7 Issue 5 Pages 415-418
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSDownload PDF (236K) -
Tatsuo SATO, Kaoru YOSHINAGA, Atsushi OIKAWA, Tatsuo TORIKAI1966 Volume 7 Issue 5 Pages 419-429
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSDuring the period from 1950 to 1965, a total of 85 patients with pheochromocytoma were reported in Japan. The clinical data on these patients were reviewed and analyzed in comparison with those of Western investigators.View full abstractDownload PDF (515K) -
Tachio KOBAYASHI, Terutomo KAJIHARA, Hirofumi OSADA, Utako KOMIZO, Kok ...1966 Volume 7 Issue 5 Pages 430-437
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSDuring the infusion of H3-epinephrine or H3-norepinephrine (0.15μg./Kg./min.) for 30 to 60min. in 18 patients, nitroglycerin was administered to 6 cases with angina pectoris. The radioactivity of H3-epinephrine or H3-nor-epinephrine in plasma and urine and its H3-acidic metabolites in urine were estimated in all cases. Similar measurements in the myocardium and plasma were carried out in 6 rabbits (3 non-treated and 3 pre-treated with nitroglycerin 3min. before the infusion of H3-norepinephrine).
From these studies, it is postulated that this drug acts as an accelerator of catecholamine inactivation. Further investigation will be needed.View full abstractDownload PDF (411K) -
Hideo UEDA, Tadashi KOIDE, Masahiko IIZUKA, Iwao ITO1966 Volume 7 Issue 5 Pages 438-447
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESS(1) Hemodynamic effect of a β-adrenergic blocker (propranolol) was studied in tilted position in 40 cases of non-anesthetized human subjects.
(2) Heart rate and cardiac index in recumbent position were slightly lower in cases treated with propranolol than in control cases.
(3) Propranolol abolished the increase in heart rate with tilting, with concomitant accentuation of the decrease in cardiac index. Stroke index remained unchanged. Slight increase in heart size was also suggested.
(4) Systolic blood pressure tended to decrease with propranolol in upright position, but diastolic blood pressure showed little change.
(5) Propranolol showed no effect on blood shift with tilting.
(6) Importance of β-adrenergic drive of the heart in tilted position wassuggested from these data.View full abstractDownload PDF (534K) -
Toshimasa OGAWA, Hideo TAKADA, Shinji YOSHIDA, Sumio HISADA, Kazuo HOR ...1966 Volume 7 Issue 5 Pages 448-459
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSThe intensity distribution of systolic murmur on chest surface was examined on 7 patients with ventricular septal defect. The frequencies of 79, 100, 200, 400 and 800cps were investigated. On the chest surface the equal intensity contour lines of the systolic murmur in ventricular septal defect were of approximately concentric circles centering around the point of maximum intensity of the murmur for each frequency.
On the frequencies of 79, 100, 200 and 400cps, the relationships between the relative intensity in decibels of the murmur and the distance from the point of maximum intensity of the murmur were inversely proportional. Andthe apparent dampings per cm. of distance were from 0.4 to 1.8dB/cm. for 100cps, 0.4 to 2.0dB/cm. for 200cps and from 0.7 to 3.3 dB/cm. for 400cps. On the frequency of 800cps, the apparent damping become smaller according as the distance from the point of maximum intensity increased, in 4 of 7 cases. The apparent viscous damping obtained from the present data was generally smaller than the viscous damping of the sound during the transmission over chest surface.View full abstractDownload PDF (602K) -
II. The Use of Compressor PhonocardiographTsuguya SAKAMOTO, Chuichi SATO, Tetsuro YAMADA, Zen'ichiro UOZUMI, Hid ...1966 Volume 7 Issue 5 Pages 460-473
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSThe compressor circuit for the comprehensive study of the cardiovascular sound was described. This circuit arranges the intensity distribution of the precordial vibratory spectrum by a non-linear amplification using diodes. When used with the conventional high-pass filter (compressor phonocardiography), it has a superiority to pick up the feeble vibrations of both low and high frequency ranges, and thus a single high-pass filter permits the recording of both low and high frequency vibrations comparable to those supplied by several conventional filters. Therefore, the number of filter may be reduced. Tentatively, 50/6 and 400/24 filters are satisfactory to pick up all the features of the cardiovascular sounds when the compressor is used properly. Furthermore, because the large vibration is selectively attenuated, a certain width of the recording paper becomes to be available for more beams. Reduced number of filter, the compressed amplitude of the large vibration and the stable baseline, all permit the polygraphic recording and this is particularly preferable to the functional phonocardiography which requires both low and high frequency phonocardiograms from the various auscultatory areas simultaneously. Several cases were illustrated to explain the above-mentioned statement, and the comments were made on the erroneously introduced misconcept of the phonocardiography.View full abstractDownload PDF (3291K) -
Motoomi NAKAMURA, Yasushi ISHIHARA, Teizo SATA, Shinichiro TORII, Akin ...1966 Volume 7 Issue 5 Pages 474-486
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSPurified diets containing cholesterol, cholic acid and different levels of magnesium with or without glycyrrhizin and Mg-K-Aspartate were fed to young growing rats for 138 days. The mild diet-induced magnesium deficiency resulted in poor growth, hypomagnesemia, an increased production of atheromatosis of aorta and heart valves, a profound calcification of kidney, an increase of calcium concentration of kidney, a slight decrease of magnesium concentration in kidney and myocardium, increases of cholesterol, glycerol and phosphorus in lipid fraction of serum, and an increase of weight of the liver and spleen. Rats receiving a dietary glycyrrhizin showed an increase of magnesium concentration of myocardium, decrease of magnesium in serum, a decrease of cholesterol in serum, increase of glycerol and phosphorus in lipid fraction from liver and decrease of glycerol and phosphorus in lipid fraction from serum.
Rats fed a diet containing 24mg. of magnesium per 100Gm. of diet without cholesterol and cholic acid, showed a conspicuous calcification of kidney, suggesting that 24mg. of magnesium per 100Gm. of diet is insufficient. Rats receiving a dietary magnesium in a form of Aspartate instead of MgO, had a decreased concentration of glycerol and phosphorus of lipid fraction in serum, and an increase of magnesium in myocardium.View full abstractDownload PDF (2160K) -
Hideo UEDA, Masahiko IIZUKA, Hisakazu YASUDA, Tetsuji IIZUKA, Masashi ...1966 Volume 7 Issue 5 Pages 487-493
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSEffects of electrical stimulation of mesencephalic pressor areas on peripheral hemodynamics were investigated in isolated hindlimbs of the dogs anesthetized with α-chloralose. Perfusion pressure and venous outflow were measured in the isolated hindlimbs perfused at constant flow.
(1) Perfusion pressure gave triphasic changes by the stimulation.
(2) The first phase is caused by vasoconstriction via vasoconstrictor nerves.
(3) The second phase corresponds with vasodilatation via cholinergic vasodilator nerves.
(4) The third phase is delayed vasoconstriction mediated by humoral pressor substances.
(5) Increase in venous outflow, independent of perfusion pressure, indicates venoconstriction by the stimulation.View full abstractDownload PDF (1611K) -
Koki SHIGENOBU, Akimitsu KAMIYAMA, Keijiro TAKAGI, Kojiro MATSUDA1966 Volume 7 Issue 5 Pages 494-504
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSActions of pronethalol on the electrophysiological properties of the mammalian heart muscle were investigated. Pronethalol decreased the pacemaker activity of the ventricle (right bundle branch of dog) and of the sinus node (rabbit). Conduction velocity, critical membrane potential and maximum depolarization rate were all reduced by pronethalol. Absolute and relative refractory period were prolonged, and Na-inactivation curve shifted to the right (inhibition of Na-carrier system) by pronethalol, whereas no or little effects, if any, were observed on the resting potential and membrane resistance in resting and acting phases.
The mechanism of antiarrhythmic action of pronethalol was discussed, and it was concluded that the mechanism is not the same as that for the wellknown beta-blocking action of pronethalol.View full abstractDownload PDF (449K) -
I. The Ectopic Pacemaker Formation in the Left Superior Vena Cava Proximal to the Heart and the Genesis of Cardiac ArrhythmiasTakasi YANAGA, Morio ITO, Kazuyuki SAEKI, Makoto ARITA, Mitsuo TANOUE, ...1966 Volume 7 Issue 5 Pages 505-511
Published: 1966
Released on J-STAGE: December 09, 2008
JOURNAL FREE ACCESSThe ectopic pacemaker formation by aconitine in the left superior vena cava proximal to the heart was studied in rabbit.
(1) Aconitine produced the automatic activities in the isolated strip of vena caval muscle.
(2) During the recovery from aconitine poisoning the action potentials with diastolic slow depolarization were recorded from the region of the left superior vena cava near the coronary sinus.
(3) In the in situ experiment, tachycardia was produced by the local application to the left superior vena cava near the coronary sinus.
(4) From the above-mentioned facts, it was suggested that aconitine induced the ectopic pacemaker in the left superior vena cava proximal to the heart and that the impulse from the ectopic focus spread not only to the periphery but also to the atrium.View full abstractDownload PDF (1132K)
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