The epidemic of rubella in the United States in 1964 was followed by the birth of many thousand of infants with congenital rubella syndrome. Many investigators reported the new clinical manifestations during newborn period in addition to symptoms of the classical rubella syndrome described by Gregg.
Although congenital abnormalities following maternal rubella has been fully documented, such cases were regarded as rare among the Japanese before 1965. In 1965, a malignant epidemic of rubella occurred in Okinawa, and it brought with more than 361 cases of congenital rubella syndrome. A retrospective study was conducted on those cases for past 4 years, and a criteria for retrospective clinical diagnosis of congenital rubella syndrome was established on the bases of the clinical manifestations and serological data.
Group 1. Congenital Rubella Syndrome
Rubella retinopathy and in addition one or more symptoms among congenital cataract, congenital heart disease (CHD) and congenital deafness. If funduscopy unable, all of the three symptoms.
Group 2. Suspected Congenital Rubella Syndrome
Deafness only with history of maternal rubella. Two symptoms among cataract, CHD and deafness with or without history of maternal rubella.
Group 3. Rubella Retinopathy only
Group 4. Normal
No clinical manifestation with or without history of maternal rubella.
It includes the cases of subclinical congenital rubella.
Group 5. Others
Cataract only and CHD only with or without history of maternal rubella.
Deafness only without history of maternal rubella.
Miscellaneous
Rubella retinopathy was the most important clinical manifestation for the retrospective diagnosis of congenital rubella. Among 171 cases with rubella retinopathy serologically examined, 167 (97.790) were positive of rubella HI antibody, and about 70% of rubella deafened children had rubella retinopathy.

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The authors reported a case of rhinogenic sinus cavernous thrombosis, spreaded into sigmoid sinus land internal jugular vein, discussed its diagnosis and treatment.
The case was 28 years female suffering from acute onset severe frontal headache, high fever (39°), left exophthalmos. Rhinoscopic and x-ray examination suggested left acute purulent sinusitis. In spite of Luc-Caldwell maxillo-ethomoidectomy and extranasal frontal sinus operation and antibiotics, remittent fever, slight stiffness of neck, inflammatory swelling of left lateral neck along internal jugular vein, granulation from posterior auditory canal appeared. Chemosis, diminished visual acuity, left III IV VI cranial nerve disturbances were recognized. Cerebrospinal fluid finding showed aseptic meningeal reaction, left Queckenstedt Sign was positive.
Second operation of internal jugular vein ligation, mastoid and sigmoid sinus opening had done, and thrombophlebitis of internal jugular vein and sigmoid sinus, mastoiditis were confirmed.
The patient had dramatical recovery after the second operation, left the hospital 3 weeks later, but left blindness, III IV VI cranial nerve disturbances did'nt healed.
In relation to the effect of venous ligation and removal of clotted blood, we supposed supprative focus would be in sigmoid sinus, purulent blood would flow in general circulation system, and about the propriety of anticoagulant treatment discussed.
Long coursed cavernous sinus thrombosis would not seldom extend to sigmoid sinus and internal jugular vein, so observation on these area is important. On the extended case the ligation of vein or the removal of supprative focus must be done at the proper stage.

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A patient of 9 years old boy who, before surgery, had no obvious symptom or signs of chronic otitis media, showed manifestations of otogenic intracranial complication. Inspite of good general condition after surgery, the patient died with sudden apnea 11 days postoperatively. Although autopsy could not be done, it was presumed that brain herniation resulted from a latent cerebellar abscess. The symptom and postoperative course of the case were described in detail and compared with those of cases presented by other authors.

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A school-girl, eighteen years old, was attacked by tinnitus, hearing disturbance on the left side and vertigo in August, 1966.
On the 12th of October of the same year she was attacked again by vertigo and nausea. When she visited the ENT clinic of Kochi Prefectural Central Hospital, it was discovered by audiometry that she had a perceptive deafness in the left ear. It was discovered through ENG that she had positional nystagmus to the left with the eye closed. Left CP was also proved to be in her.
About two years from that time she suffered from the occasional attacks of vertigo. During this period she was examined repeatedly with the audiometer. Her audiogram showed no change at all. But at the 4th of December, 1968, her audiogram recuperated to the normal range.

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There are two opinions about good bone conduction auditory sense of nervous hardness of hearing in low frequency areas.
That is vibrotactile exteroception theory and vestibular hearing theory.
For vibrotactile exteroception theory, if an examiner has good understanding for an examinee, the latter can distinguish difference between vibratory sense and auditory sense.
For vestibular hearing theory, I do not think there is parallelism between the quality of vibratory sense and vestibular function as Bocca says, but cannot deny his opinion.

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We are generally impressed that tinnitus is accompanied and runs parallel with deafness. And we also are concerned in the fact that there are some who are deaf without tinnitus and some who have tinnitus without deafness. If tinnitus and deafness occur from different mechanisms, these facts are not incoherent. But if tinnitus and deafness occur from one and same mechanism, is not it strange that there are some exceptional cases observed? Such a contradiction that some patients suffer from deafness without tinnitus caused in the same mechanism can be solved only by thinking that it is due to the psychological reason.
We examined with Cornell Medical Index the next three groups: the first was a group of persons who had tinnitus and deafness (22 persons), the second were tinnitus-persons without deafness (7 persons), the third were deaf persons without tinnitus (32 persons).
The results are as follows;
1) Tinnitus-persons showed more neurotic tendency than normal persons. They were deeply concerned in their own health.
2) The persons without tinnitus were comparatively indifferent to themselves physically and mentally. Many persons of this group, however, complained of fearful dreams. Such dreams, in our opinion, are the manifestation of tinnitus of which the patients are not concious.
3) The tinnitus-persons without deafness show a strong tendency of depression.
Conclusion: The existence of a group of persons who have deafness without tinnitus is not a contradiction even if tinnitus were caused in the same mechanism as deafness.

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球形のうおよび卵形のう感覚上皮におけるI型細胞およびII型細胞を識別するために, その取出し標本に銀反応が応用され好結果が得られた. striolaにおいては約2/3の感覚細胞はI型細胞であつた. しかし感覚上皮全体では, II型細胞がI型細胞より多く認められた. その比率は球形のう感覚上皮で約1.0対1.2, 卵形のう感覚上皮で約1.0対1.1であつた. I型および豆型感覚細胞の分布様式は, 銀反応後感覚上皮の取出し標本を強拡大にて分割写真撮影し, それを組合わせたのち, 正確にインキを用いて描写することにより図示された.

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1. 61才男の左中耳腔内に原発したと思われる聴器癌症例について, その臨床経過と剖検所見について述表4中耳癌と慢性中耳炎との鑑別診断表5 Treatment妹尾・瀧口・松原・宮崎=多数の神経症状を呈した中耳癌の一剖検症例265べた.
2. 本症例は多数の脳神経症状を呈しながらも, Vernet頸静脈孔症候群, Glomus jugulare tumor, 頭蓋内腫瘍との鑑別が遅れ, あらためて中耳癌の診断の困難さを痛感させられた.
3. 剖検所見において腫瘍が錐体および鼓室部全体に浸潤していたにもかかわらず, 脳硬膜を破つて頭蓋内に浸潤していたのはごく一部で, 腫瘍に対して脳硬膜は非常に大きな抵抗性を有することが分つた. また中耳癌の遠隔転移が少ないことも判明した.
4. 中耳癌の発生頻度, 性別および年令, 病理, 来院時の症状, 診断および慢性中耳炎との鑑別, 治療について, 諸家の報告をまとめて検討してみた.

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Bezüglich der Fernmetastase des Kehlkopfkarzinomes gibt es in der japanischen Literatur nur wenige Beschreibungen. Diese Tatsache scheint darauf zu beruhen, daß es infolge des hohen Heilungsquotienten des Kehlkopfkarzinomes wenige Sektionsfälle gibt und die Metastasen sich häuptsachlich am Halse oder in der Lunge lokalisieren.
Wir batten neulich eine Gelegenheit, einen solchen Fall des Kehlkopf-karzinomes mit Fernmetastasen zu behandeln und nach dem Tod die Leiche zu obduzieren. An Hand dieses Falles mochten wir unsere Überlegungen fiber die Fernmetastase des Kehlkopfkarzinomes berichten.
Die pathologisch anatomische Diagnose dieses Falls wurde wie folgt gestellt:
1. Status post operationem (Tracheotomie),
2. Kehlkopfkarzinom (Plattenepithelkrebs),
3. Metastasenbildungen und die karzinomatose Infiltration an der Speiseröhre, am Herzen, an beiderseitigen Lungen, am Zwerch-und Bauchfell, am Darm, an beiderseitigen Nieren, an den 5. und 7. Brustwirbeln und an Lymphknoten (Lnn. cervicales, paratracheales, mensenterii et retroperitonei),
4. Hydroperikard und Hydrothorax,
5. Lungenödem und
6. braune Leberatrophie.

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Six cases of pap illomas in the nasal cavity and paranasal sinus were studied clinicopathologically. The age of the patients ranged almost in fifties. This disease should be distinguished from maxillary cancer or nasal polyp due to chronic sinusitis. Final definite diagnosis of papilloma based on the histological examination and several differences between the papillomas in the nasal cavity and the papillomas in the paranasal sinus were observed clinically and microscopically. The papillomas in the nasal cavity or choanae were hard and smooth, and histologically the thick epithelial proliferation and rich stroma were found. On the other hand, the papillomas in the paranasal sinus were soft and cauliflower-like, and thin epithelial layer and poor connective tissue were seen. The term “inverted papilloma” named by ASH, et al. must be the most suitable one. One case has squamous cell carcinoma together with papilloma and some papillomas might be precancerous condition or semimalignant. However, the total maxillectomy or irradiation in the treatment of papillomas is not always required. Five patients of the six cases have been in health without recurrence more than two years after operations.

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