巻号一覧
25 巻, 4 号
選択された号の論文の12件中1～12を表示しています
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奥田 稔, 関根 啓一, 河野 寿, 金 善坤, 海野 徳二, 打越 進, 小上 芳春, 大塚 博邦, 川堀 真一, 富山 俊一, 宇佐神 ...1979 年 25 巻 4 号 p. 1197-1208
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーDuring the past ten years 285 cases of head and neck cancers were treated at Wakayama Medical College Hospital. For the treatments the following new methods were deviced and applied. 1) In maxillary cancer the simultanous combined use of instillation of Phytohemaggultinin solution into the sinus with Co60 irradiation and intraarterial infusion with 5 Fu induced histological disappearance of tumor cells in 61.1% of the cases. 2) New reconstructive techniques were successfully applied to operations for cancer of the oral cavity, hypopharynx and thyroid. The mouth floors were reconstructed by a pedicle flap of the epithelial layer of the tongue, and hypopharynx walls were done by a cervical skin flap under a special skin incision, and cervical tracheas by a free composite graft of nasal septum. 3) Cryosurgery was employed for cancer of the maxillary sinus and oral cavity. 4) Flexible bonchofiberscope was used to examine the extent of development in laryngeal and large cervical esophageal cancer.
As the end result of treatment three years crude survival rate of cancers of the maxillary sinus, larynx, oral cavity, epipharynx, mesopharynx, hypopharynx, cervical esophagus, thyroid and salivary gland were 53.1%, 75.0%, 36.4%, 0%, 42.8%, 66.6%, 30.0% 64.0%, 70.0% respectively.
The causes of death were characteristic according to the site of cancer. Death due to local recurrence was frequently seen in cancer of the oral cavity, maxillary sinus, pharynx and esophagus which, if invaded deeply into the surrounding structue of muscles, resisted to irradiation or escaped from complete excision. Death due to local metastases was frequently seen in cancer of the oral cavity, supraglottis of larynx, hypopharynx and cervical esophagus, of which metastatic foci involved the wall of carotid artery. Death due to distant metastases was frequently seen in cancer of the epipharynx of which histological type was undifferentiate. Death due to causes other than recurrence of the cancer was frequently seen in cancer of the maxillary sinus, larynx, hypopharynx and cervical esophagus of which patients were already in general condition of high risk before treatment or had disturbance in feeding or secondary immunodeficiency during the treatment.抄録全体を表示PDF形式でダウンロード (1761K) -
野村 恭也, 小林 武夫, 川端 五十鈴, 本多 清志, 和久井 孝太郎1979 年 25 巻 4 号 p. 1209-1212
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーA right-angled needle scope is developed using the Selfoc rod lens. This enables us to observe structures and pathological tissues within the middle ear cavity. Through a small central perforation of the tympanic membrane, the following structures can be observed: handle of malleus, long process of incus, incudostapedial joint, stapes, stapedial tendon, pyramidal eminence, round window, tendon of tensor tympani, ponticulus and subiculum.
Without any anesthesia, we are able to introduce the scope (1.7mm in diameter) into the tympanic cavity of children through a central perforation. A teaching scope is coupled the needle scope to a high sensitivity TV camera (ASA 30000). Thus observation fields are videotaped and projected on TV screen.
The needle scope is found to be useful in making preoperative diagnosis of middle ear diseases and in evaluating the extent of diseases.
As the round window can be seen, a perilymph fistula may be endoscopically diagnosed after myringotomy.抄録全体を表示PDF形式でダウンロード (4738K) -
麻木 宏栄, 杉原 三郎, 生駒 尚秋1979 年 25 巻 4 号 p. 1213-1217
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーCongenital jerky nystagmus was observed in a 15 year-old boy with electronystagmography. With forward gaze beyond 2 meters, the ampulitude and frequency of his nystagmus were increased. However, with his right eye close, its ampulitude and frequency were decreased. When the eyes was closed, the nystagmus was remarkably reduced. But, with screening his eyes, the nystagmus was not changed. We made a review of literatures reporting the treatment of congenital nystagmus.抄録全体を表示PDF形式でダウンロード (721K) -
北島 敦子, 西田 之昭, 安田 宏一1979 年 25 巻 4 号 p. 1218-1223
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーWhen a 31-year-old man, lying on his left side, was cleaning his right ear with an earpick made of bamboo, his child touched the earpick by accident. In no time at all, he developed earache, tinnitus and hearing impairment. On the 6 th disease day pullsating otorrhea occurred. Otologic examination revealed severe sensori-neural hearing loss in the right ear with a prolonged rightward nystagmus. An antibiotic drug regimen coupled with blockage of the stellate ganglion brought about, in about one and a half months, an arrest of the otorrhea and recovery of hearing to a level of 30 dB on the average. The nystagmns also disappeared. A test for vestibular function (rotation test) demonstrated no residual abnormalities with no left-to-right differences.
Of great interest is the fact that the patient restored his hearing to a conversable level after sustaining an injury to the inner ear with a leak of perilymph and probable damage of hair cells of the cochlea. This favorable outcome is probably explained by the intactness of endolymph which facilitated return of function to hair cells with recovery of perilymph.抄録全体を表示PDF形式でダウンロード (537K) -
鈴木 衛, 渡部 直樹, 杉本 嘉朗1979 年 25 巻 4 号 p. 1224-1229
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーA case of tuberculous otitis media is reported. The patient is a 5-year-old girl, who complained of the left aural discharge and the swelling of the left cervical lymphnode. The otoscopic examination showed a whitish granulation and purulent discharge in the left ear. The results of the routine pure tone audiometry was a conductive hearing loss of 30-40 dB. Two months after the initial consultation, the diagnosis of tuberculous otitis media was established by culture of the aural discharge. After general administration of streptomycin, INAH and PAS, as well as topical application of streptomycin, the patient has been free from the aural drainage and the cervical lymphadenitis.抄録全体を表示PDF形式でダウンロード (6764K) -
山崎 芳樹, 藤田 彰1979 年 25 巻 4 号 p. 1230-1237
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーRelapsing polychondritis is a systemic inflammatory disease of cartilaginous tissues affecting the cartilages of the ear, nose, larynx, trachea, bronchi and joints as well as costal cartilage. Transient painful swelling occurs in areas involved. The disease also gives rise to ocular symptoms, hearing loss, vestibular symptoms, fever and general malaise. Characteristically it is subject to acute exacerbations and spontaneous remissions. The disease being exceedingly rare, few cases have so far been reported in Japan. The purpose of this paper is to present an interesting case experienced by us in which drug therapy brought about a marked improvement of hearing in speech frequency ranges. In this case the patient was a 53-year-old policeman who suddenly developed vertigo and hearing loss and tinnitus in his left ear in the presence of chondritic involvement of cartilages of the nose, auricle and larynx as well as of conjunctivitis and iritis. Treatment consisted of steroid, antibiotics and Vitamin Complex, in respective daily doses of 20mg, 2g and 1 ampoule, and this combined drug regimen, which was continued for a considerably long time, produced a marked improvement of hearing in his left ear at speech frequency levels. It seems that this fact provides evidence in support of the hypothesis of Cody et al. that hearing loss associated with the disease in question might be due to arteritis of the cochlear artery. The world literature on impairment of hearing associated with relapsing polychondritis is reviewed.抄録全体を表示PDF形式でダウンロード (6769K) -
Drug-induced Hepatic Injuryについて調 賢哉1979 年 25 巻 4 号 p. 1238-1244
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーDrug-induced hepatic injury has recently become one of the most urgent problems in medical practice in Japan. The author had an experience to treat a 70 year-old male who had laryngitis phlegmonosa acuta. During the treatment he got affected with fulminant hepatitis caused by drug-induced hepatic injury. The causative drug in this case was deduced to be cepharosporin or tetracyclin. From this case and the literature referred to the author discussed drug-induced hepatic injury as follows:
1) Most cases of drug-induced hepatic injury can be referred to allergic reaction. And allergic hepatitis cases very often assume chole-static hepatitis. In order to diagnose for this type of hepatic injury at an early stage, a careful observation of general findings is indispensable as well as the examination of serumbilirubin and alkali-phosphatase. For the diagnosis of drug-induced hepatic injury at an early stage this examination is more significant than serum-transamilase test (GOT, GPT).
2) When hearing the clinical history, we should be careful enough to see if druginduced hepatic injury had existed or not in the patient's past history. This check-up is profitable to prevent the case from developing into fulminant hepatitis by the readministration of the same drug as caused hepatic injury.抄録全体を表示PDF形式でダウンロード (836K) -
松尾 浩一, 三橋 重信, 栗田 茂二朗, 大西 克貞1979 年 25 巻 4 号 p. 1245-1249
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーChondrosarcoma of the maxilla is a rare but distinct clinical entity. A 25-year-old woman developed a mass of the upper gingiva on the right side. Repeated biopsy revealed that the mass was chondrosarcoma. The patient was treated with partial maxillectomy. No recurrence has been observed for 7 months. A review of leterature was made in particular on treatments.抄録全体を表示PDF形式でダウンロード (8372K) -
渡辺 晋1979 年 25 巻 4 号 p. 1250-1270
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーIt has been known that the patient with unilateral vestibular dysfunction shows a unique deviation reaction called the “discus-thrower position”. This study was aimed to clarify the background of appearance of the “discus-thrower position” on testing various equilibrium function tests. Results were as follows;
1. Comparative study was made on the evocation of nystagmus in various ocular positions by the optokinetic nystagmus test as well as by the caloric test without gaze. It was confirmed in the assurance that nystagmus was easily evoked when his eye balls was turned to the direction of the quick phase of nystagmus. In the cases with a horizontal paralysis or a vertical paralysis of oculi muscles the ocular position, which easily evoked optic nystagmus, was situated in the eccentric position contralateral to the paralytic side. Accordingly, these findings should be taken into consideration in performing a test in cases of ophthalmoplegia. It may be occurred as follows: There might be the position抄録全体を表示PDF形式でダウンロード (5558K) -
森本 大和1979 年 25 巻 4 号 p. 1271-1282
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーIn this paper, the relationship between sensation of the nasal obstruction and the nasal resistance (Rn) was evaluated by following method. The Rn of each nasal airway of 72 sides of 36 cases complained of various grades of nasal obstructions and 12 cases without them were separately recorded by combined method using pneumotachomerer. Sensation of the nasal obstruction was classified into 4 grades. The Rn was calculated according with Rohler's formula.
In normal subjects, the mean value of Rn at the flow rate of 0.1 LPS was obtained 2.9cm H2O at expiration and 2.8 cm H2O at inspiration. In the cases complaining of severe nasal obstruction, Rn was highly correlated with the subjective sensation. In the cases of slight nasal obstruction, total Rn was observed almost within normal range and there was no correlation between total Rn and their complaints.
The Rn of each separately being measured, the Rn of the obstructed side was correlated with their complaints. The choice of the method to measuring the resistance of each side of the nasal airway is usufull for detecting the slight nasal obstruction. In the cases of nasal allergy just having been provocated with disk method, there is a high correlation between Rn and their sensation of the nasal obstruction. After surgical restoration for the obstruction due to chronic changes such as nasal polyps, the Rn sometimes does not revert to the normal range. In some cases which their Rn were recorded still high, there are no complaints of nasal obstruction. In the cases with chronic nasal inflammatory diseases, Rn is not always correlated with their sensations of nasal obstruction.抄録全体を表示PDF形式でダウンロード (1453K) -
至適用量, 薬効, 安全性について奥田 稔, 仙波 治, 高橋 光明, 矢島 洋, 海野 徳二, 星野 忠彦, 藤原 隆行, 今野 昭義, 高坂 知節, 郭 安雄, 佐々木 ...1979 年 25 巻 4 号 p. 1283-1309
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーIntranasal beclomethasone dipropionate was given to 245 patients with perennial nasal allergy for a week in 17 institutions. The optimum dose, clinical effects and safety of the drug were studied.
1. One puff into each nostril four times a day (400μg) was more effective than one puff twice a day (200μg) in adults. In children, the efficacy of one puff twice a day (200μg) was comparable to that of one puff four times a day in adults. Overall improvement rate was 81.2% with four doses a day (400μg) and 58.6% with two doses a day (200μg) in adults. Children showed overall improvement in 76.2% with two doses a day (200μg).
2. The efficacy was confirmed by doctor's evaluation, questionnaire filled out by patients, patients daily records, and clinical data of rhinoscopy, examination of nasal eosinophils and nasal provocation test.
3. Almost no side effects except local irritation (9.7%) were observed and they were slight, if any. Plasma cortisol levels did not change before and after treatment. Thus, high usefulness was obtained; i. e, 77.0% with four doses a day and in 51.7% with two doses a day for adults and in 76.2% with two doses a day for children.抄録全体を表示PDF形式でダウンロード (2657K) -
広戸 幾一郎, 笠 誠一1979 年 25 巻 4 号 p. 1310
発行日: 1979/08/20
公開日: 2013/05/10
ジャーナル フリーCystが腫瘍の一種であるとの考えで嚢腫と呼ばれていた頃は外科的治療は全摘出術であったが, 非腫瘍であるとして嚢胞と呼ばれるようになってからは排液路をつくるだけのdrainage手術が奨用されるようになった. 術後性上顎嚢胞に対する手術法の変遷がその良い例である. しかし嚢胞の内容を排液する部位が鼻腔のように湿溜し, 異物進入の危険が少ない部位ではいいが, そうでない時には依然として全摘出術を施行せざるをえない. 軟口蓋耳下腺嚢胞の場合にも, 咽頭に開孔するdrainage手術は食物進入の危険を考えて一顧も与えられていなかった. しかしdrainage手術は最も簡便な手術法であるので, 多少の危惧をもちながら施行したところ, 術後3年の現在まで無症状で順調に経過しており, 試みるべき価値ありと思うので報告する.抄録全体を表示PDF形式でダウンロード (2389K)
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