巻号一覧
28 巻 (1982)
- 6 号 p. 1075-
- 5Supplement3 号 p. 835･･･
- 5 号 p. 739-
- 4Supplement2 号 p. 649･･･
- 4 号 p. 549-
- 3 号 p. 449-
- 2Supplement1 号 p. 281･･･
- 2 号 p. 161-
- 1 号 p. 1-
28 巻, 5Supplement3 号
選択された号の論文の33件中1～33を表示しています
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末永 通, 大橋 正實, 寺山 吉彦, 田中 克彦1982 年 28 巻 5Supplement3 号 p. 835-839
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーViral infection is believed to be one of the causes of sudden deafness. The circulating interferon (IFN) assey can detect viral infection at early stage.
The circulating interferon (IFN) of 31 patients of sudden deafness (41 samples) were asseyed by means of 50% cell pathological effect (CPE) reduction method in microplate using FL cell-Vesicular Stomatitis Virus (VSV) system.
The samples were obtained within a few days from the onset of the hearing loss.(Twenty-seven were within a week.) No interferon activity was detected in the patient serums. At the same time, the detection of the virus particle from serum of the patient, by CPE formation in FL cells and Vero cells, was performed. No CPE was observed after 7 days in FL cells, and 10 days in Vero cells from the innoculation. This work did not indicate the relationship between viral infection and sudden deafness.抄録全体を表示PDF形式でダウンロード (554K) -
寺山 吉彦, 大橋 正実, 松島 純一, 松浦 聖一1982 年 28 巻 5Supplement3 号 p. 840-844
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーThere are three types concerning onset of the hearing loss in definition of sudden deafness in foreign countries: a) instant onset, b) awake on awakening in the morning, c) development of deafness over a period of a few hours or days. In Japan, however, it is limited to the cases of a) and b). The cases of c) was tentatatively called by the authors “Rapidly Progressive Sensorineural Hearing Loss”(or Rapid Deafness).
The results of examinations of 9 cases (5 males and 4 females, aged 15-52) whose deafness developed within an hour to 3 days were reported. Their averaged hearing loss in dB at 5 frequencies at initial visit was 53-89 dB and-7-60 dB at fixed stage. The prognosis was complete cure in 5 (3 spontaneous cure), markedly improvod 2, improved and unchanged 1 respectively. Except for the following points, rapid deafness showed no difference from sudden deafness: 1) Speed of progress of hearing loss, 2) Various matters exist in their history except for 2 cases, 3) Number of days from onset to cure was two times longer than in sudden deafness. The authors conclude that rapid deafness should be examined and treated as same as for sudden deafness, but differently diagnosed until collection of a mass of the cases is available.抄録全体を表示PDF形式でダウンロード (686K) -
荘 烱欣, 川端 五十鈴, 野村 恭也1982 年 28 巻 5Supplement3 号 p. 845-849
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーObservations were made on the development of the round window and its membrane in human embryos. Materials subjected to this study were nine fetuses of 8-36 weeks with C. R. length of 20.7mm, 50.5mm, 60.0mm, 72.0mm, 84.0mm, 155.0mm, 184.0mm, 205.0mm, and 313.0mm respectively. After these materials were fixed with formalin and embedded in paraffin, serially sliced specimens of 5 Am were prepared. The following findings were obtained from this study:
1. Crista semilunaris located at the bottom of the Niche of the round window protruded from the prominentia utriculoampullaris inferior of the canaliculicular part, and was shaped by ossification of cartilage in about 22 weeks.
2. Niche of the round window was related to the hiatus tympanomeningealis, which was the passageway from the cranial cavity to the middle ear.
3. The round window membrane was partly produced by the dura-like structure lining cell, which surrounded the cochlear aqueduct and glossopharyngeal nerve.抄録全体を表示PDF形式でダウンロード (6886K) -
奥野 妙子, 野村 恭也1982 年 28 巻 5Supplement3 号 p. 850-856
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーA model study of round window membrane rupture was carried out on human temporal bones and guinea pigs. Perilymphatic pressure was increased via the cochlear aqueduct or directly at the basal turn of the scala tympani. At the same time, we produced the negative pressure around the cochlea, like the middle ear negative pressure.
Half of the cochlear aqueducts were able to reflect the pressure. Among the perilymphatic fistulae, oval window ruptures were more produced than round window ruptures. Ruptures of the round window membranes were slit-like perforations along the fibers of the membranes.抄録全体を表示PDF形式でダウンロード (1210K) -
原田 勇彦, 川端 五十鈴, 野村 恭也1982 年 28 巻 5Supplement3 号 p. 857-862
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーPermeability of the round window membrane was investigated in normal ears and in ears with serous otitis media. Serous otitis media was produced experimentally by obstructing the eustachian tube of the guinea pig on one side. The other side served as a control. Neomycin was applied directly to the round window membrane on both sides, and the inner ear changes were observed under a light microscope. Most of the ears with serous otitis media showed no cochlear pathology or only slight chages, while moderate to severe changes were observed in all of the control ears. The results indicate that the round window membrane is permeable to neomycin, and that the transport of neomycin into the inner ear decreases in most instances of serous otitis media. The latter may be explained on the basis of fluid remaining and blocking the transport of neomycin mechanically on the surface of the round window membrane.抄録全体を表示PDF形式でダウンロード (1425K) -
深谷 卓, 野村 恭也1982 年 28 巻 5Supplement3 号 p. 863-865
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーMiddle ear effusions were produced in guinea pigs by occluding the middle ear orifices of the eustachian tube. Then the round window membranes were incised and electrophysiological consequences were measured by ABR and EcochG.
Results are summarized as follows:
1) Incised round window membranes were healed within 30 days.
2) Subtractive loss type hearing impairments were recorded to the acoustic stimuli above 4, 000Hz.抄録全体を表示PDF形式でダウンロード (365K) -
永井 克孝, 岩森 正男, 林田 哲郎, 野村 恭也1982 年 28 巻 5Supplement3 号 p. 866-871
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーAntibodies against glycolipids (GM1, GA1, GA2, Forssman antigen, and globoside) and triphosphoinositide in the sera with sudden deafness were measured by enzyme-linked immunosorbent assay. A significant elevation in titers of anti-GA1 and GA2 antibodies which did not cross-react with other glycolipid antigens used was found in serum of a patient. The antibodies were IgM isotype and surprisingly disappeared from the serum during the course of therapy. The similar antibody with anti-GA1 specificity was detected in the sera with the same disease with probability of 30%. However, the correlation between antibody titers and clinical course of the disease was not distinct The reason why plasma cells producing these antibodies were specifically stimulated seems to be important for understanding the aetiology of the disease.抄録全体を表示PDF形式でダウンロード (588K) -
倉田 毅, 小出 純一, 本藤 良, 野村 恭也1982 年 28 巻 5Supplement3 号 p. 872-877
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーThe cause of sudden deafness is not clear, and virus infection is suspected as one of participant. Herpes simplex virus which has the strong tropism to the nervous system was inoculated directly into the inner ear through the round window, and the distribution of the viral antigen was examined by immunofluorescence in paraffin sections with enzyme treatment together with histopathological study at the different stages after virus infection. Microscopic examination revealed the fibrotic change of scala tympani, degeneration of Reissner membrane, destruction and flatness of the organ of Corti at basal turn, the change of nuclei in spiral ganglion, and the atrophy of stria vascularis. Viral antigen was demonstrated in those areas. Viral antigen was also detected in the several parts of uninfected inner ear. Virus was recovered from the most of infected inner ears at different days and uninfected ear at the 12th day after infection.
Further investigation such as the confirmation of latent infection in the inner ear system, reinfection under the existence of antibody, permeability of cochlear membrane for the virus, and the extension of the virus infection from infected ear to the non-infected side, may be required to clarify the mechanism of viral infection in the inner ear.抄録全体を表示PDF形式でダウンロード (4024K) -
本藤 良, 倉田 毅, 野村 恭也, 神崎 仁, 柳田 則之, 小出 純一, 三宅 弘1982 年 28 巻 5Supplement3 号 p. 878-884
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーA serosurvey for antibodies against type 1 and 2 herpes simplex virus (HSV) in 147 serum samples collected from 49 patients suffering from sudden deafness was performed.
1. As to the neutralizing (NT) antibody against type 1 HSV, there was no difference of positive ratio between the patients and the control group. However, the patients had higher positive ratio (78%) of complement-fixing (CF) antibody than the other group (54%). All NT-positive patients possessed CF antibody and the distribution pattern of these antibodies follows “all or none” law. The kinetic survey of the antibody titers during the clinical course revealed the no difference between acute and convalescent stages, and the follow up study for more than one year showed the constant levels of antibodies. The results suggest that if HSV is responsible for the disease as one of causes, the mechanism of infection may be related to reactivation of the latent infection.
2. The patients had the NT antibody against type 2 HSV with significantly higher ratio (43%) than the control (20%). All patients who had antibody to type 2 HSV possessed the antibody against type 1 at the same time, and this phenomenon suggests the reinfection of type 2 HSV after type 1 infection.
Further general investigation between serosurvey and clinical course is required to clarify the virus participation as the cause of the sudden deafness.抄録全体を表示PDF形式でダウンロード (737K) -
村田 計一, 堀川 順生, 伊藤 挙, 南 定雄1982 年 28 巻 5Supplement3 号 p. 885-892
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーThe acoustic reflex was studied on rats which have a wide audible frequency range extended to ultrasonic sound. Reflex activities were registered by means of EMG from the middle-ear muscles and of acoustic impedance measurment at the eardrum. Transmission loss in the middle-ear due to the reflex was estimated from decrease in amplitude of CM recorded at the round window or in the scala tympani of the cochlear basal turn. The reflex threshold of the tensor tympani muscle was lowest for sounds with frequency of 3-5 kHz and it elevated steeply at lower and higher frequenies. The stapedius reflex threshold was higher than that of the tensor reflex by ca 10 dB. The threshold for ipsilaterally applied sounds was several dB lower than that for the contralateral at frequency lower than 5 kHz, above which they were nearly same. The reflex suppressed most efficiently the middle-ear transmission of sound of several hundred Hz and the transmission loss decreased with elevation of the sound frequency up to 20 kHz. The loss could not be observed at frequencies above this, though the acoustic impedance was slightly changed in some frequencies between 20-30 kHz.抄録全体を表示PDF形式でダウンロード (821K) -
田内 光, 鳥山 稔1982 年 28 巻 5Supplement3 号 p. 893-898
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーPure tone audiometry, retrocochlear hearing test and acoustic brain stem response test were performed in 68 patients treated with hemodialysis and the following results were obtained.
1: Hearing loss was found in 103 ears of 136 test ears and the degree of hearing impairment was more significant in high frequency.
2: Retrocochlear type of hearing loss was demonstrated in patients treated with hemodialysis.
3: Retrocochlear type of hearing loss was in accordance with the level of anemia and it seemed to be improved by hemodialysis.
4: Retrocochlear hearing loss observed in patients with hemodialysis is suggested to be caused by functional disturbance rather than organic lesion.
5: The acoustic brain stem response was normal and the latency of Nv was within normal limit in our study.抄録全体を表示PDF形式でダウンロード (750K) -
板坂 恵美子, 鳥山 稔, 西山 愛子1982 年 28 巻 5Supplement3 号 p. 899-902
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーA case of Goldenhar's syndrome with associated with abnormalities of the middle ear and inner ear, which were demonstrated radiologically, unilateral seventh nerve dysfunction, macrostomia, and ventricular septal defect was reported. The radiographic findings and the clinical features of Goldenhar's syndrome are presented.抄録全体を表示PDF形式でダウンロード (2683K) -
板坂 恵美子, 鳥山 稔1982 年 28 巻 5Supplement3 号 p. 903-906
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーDeafness concomitant with mumps has been well known. This report presents interesting case of development of hearing impairment due to mumps.
Case 1, 5 year-old child gradually developed hearing impairment, finally bilateral ears was found totally deaf, and associated temporary, mild equilibrious disturbance.
Case 2, 2 year-old boy developed bilateral totally deafness after cold.抄録全体を表示PDF形式でダウンロード (984K) -
班員の集計皿井 靖長, 鳥山 稔, 神崎 仁1982 年 28 巻 5Supplement3 号 p. 907-915
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーForty seven ears from 20 males and 21 females which demonstrated fluctuating hearing impairment without vertigo were collected by our collaborators in Japan and the type of hearing loss was investigated. The ears which showed the fluctuation of hearing level only in the range of low frequencies were 21.3% and in the middle and all frequencies were 36.2% and 40.4%, respectively. Only one ear (2.1%) showed the fluctuation in the range of high and low frequencies. Therefore, all ears which sohwed the fluctuation in the hearing level were accompanied with the change of low tone frequencies.
Six patients revealed the same type of hearing fluctuation in both ears. However, each ear showed the independent fluctuation of hearing level.
The cases accompanied with tinnitus and without dizziness were 86.8% and 84.1%, respectively.抄録全体を表示PDF形式でダウンロード (932K) -
石戸谷 淳一, 鳥山 稔, 佐藤 清祐1982 年 28 巻 5Supplement3 号 p. 916-922
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーWe studied six members in two generations of a family. A 27-years-old girl and her 48-years-old sister were affected sensorineural hearing loss, cataract, retinal ditachment and thyroid abnormality. Their hearing loss appeared in childhood and has been deteriorated in adult. Cataract and retinal ditachment were demonstrated at the age of 20-30, and the operation was done. Thyroid abnormality in hypofunction in younger sister and goitor in elder sister. Perclorate test was not done. A brother was affected with unilateral sensorineural hearing loss and his probability of retinal ditachment was postulated by ophthalmoscopy. Their father had sensorineural hearing loss. The other members were not diagnosed to have the similar disorder.抄録全体を表示PDF形式でダウンロード (6425K) -
川城 信子, 古賀 慶次郎, 荒木 昭夫, 脇 喜久子1982 年 28 巻 5Supplement3 号 p. 923-927
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリー1) Seven children with sudden deafness were reported.
Their ages ranged from 5 years 8 months to 12 years 3 months. Children elder than 5 years old seemed to be able to perceive the sudden onset of hearing impairment and to complain of it.
2) The results of audiometric tests were as follows:
3 cases total deafness
3 cases high frequency deafness
1 case low frequency deafness
3) Five cases complained of tinnitus and 4 cases had dizziness of shortduration.
4) Clinical courses of 7 cases were as follows:
2 cases healed
1 case slightly improved
4 cases no improvement抄録全体を表示PDF形式でダウンロード (515K) -
古賀 慶次郎, 川城 信子, 荒木 昭夫, 脇 喜久子1982 年 28 巻 5Supplement3 号 p. 928-932
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーOn 12 ears of 10 children with bilateral hearing loss, the hearing threshold SPL levels at 500, 1000, 2000 and 4000 Hz were measured either by a hearing SPL meter or a conventional audiometer. Further the output SPL levels of hearing aids of 10 children were determined while giving 60 dB input at frequencies within speech range.
Thus obtained output SPL levels of hearing aids were compared with the hearing threshold SPL levels for the individual subjects and the differences between them were evaluated. The results were as follows:
1) In cases with moderate hearing loss, the output SPL levels of hearing aids ranged over 20 dB below their hearing threshold SPL levels. In cases with severe hearing loss, the output SPL levels of hearing aids were scattered more and deviated from the hearing threshold SPL levels much greater than in cases with moderate hearing loss. The woking gain of hearing aids in everyday use was found insufficient for hearing loss of all cases in this study.
2) Five children out of 10 subjects used, for 6 months, thier own hearing aids with gain increased. In the 6 months, increase in the gain of hearing aids was found to improve their auditory acuity, though gain of hearing aids could be at most 11 dB above the hearing threshold SPL levels and could not exceed them by 20 dB.抄録全体を表示PDF形式でダウンロード (538K) -
西澤 伸志, 真鍋 敏毅1982 年 28 巻 5Supplement3 号 p. 933-941
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーDepartment Otorhinolaryngology. National Rehabilitation Center for the Disabled. Tokorozawa, Japan. One hundred and ten children with bilateral sensorineural hearing loss with unknown etiology were observed for more than five years after the first reliable audiogram obtained. Forty-five out of 110 had been followed-up until they grew up to be more than fifteen years old.
All affected ears of the children were divided into two groups. In progressive hearing loss group, ears showed more than 15 dB increasing their threshold at least two continuous frequencies, at any time during observating term comparing with the first reliable data. Others were nonprogressive hearing loss group.
The progressive hearing loss ears were 28 per cent. The ratio of progressed hearing loss ears in children observed under ten years old was 10 per cent smaller than that of in children observed over fifteen years old. In an average of hearing level in 110 cases, the final hearing level was increased more than 10 dB to the first level. The number of children whose threshold elevation was over 15 dB at 0.5 and 1 kHz was smaller, and at 2 and 4 kHz was larger than that of progressive hearing loss individuals.抄録全体を表示PDF形式でダウンロード (952K) -
神崎 仁, 岡田 拓治, 大内 利昭1982 年 28 巻 5Supplement3 号 p. 942-949
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリー1. FHLのうち原因および診断の明らかな症例を除いた16例について検討した。その結果
1) 聴力型, 聴力変動の周波数範囲, 2) グリセロール試験, 3) 蝸電図, などの所見がメニエール病確実例と類似した症例が多かった。
2. 経過観察の途中で対象例から除外された症例中には, 長期観察の結果メニエール病確実例となった例や内リンパ水腫によると思われる難聴の進行例が含まれていた。
3. 全身的検査 (血液, 血液化学, 免疫グロブリン) の所見とFHLとの関連が推察された症例はなかった。
4. 以上のことから対象例の大部分は蝸牛型メニエール病と推察された。抄録全体を表示PDF形式でダウンロード (893K) -
神崎 仁, 大内 利昭1982 年 28 巻 5Supplement3 号 p. 950-958
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリー1. Circulating immune complexes (IC) were quantitatively measured using Raji cell immunofluorescence assay in fifty-three cases with bilateral sensorineural hearing loss (SNHL), including forty-seven cases of SNHL of unknown origin, five cases of SNHL with positive syphilitic reaction and a case of aortitis syndrome.
2. High IC value (above 4μg/ml) was found in five cases (four cases of SNHL of unknown etiology and a case of aortitis syndrome). Three out of four cases of SNHL of unknown etiology responded well to steroid (predonisolone) administration, that is hearing deteriorated by discontinuation or decreased dosage of steroid and improved by readministration or increased dosage of steroid.
3. There were two cases which responded well to steroid administration irrespective of the normal IC value.
4. From the relation of IC value to steroid responsiveness, it was considered that there were some differences in the mechanisms of hearing improvement between cases with higher IC values and those with nomal IC values.
5. Steroid-responsive SNHL was seen only in female. The hearing loss developed in their forties. The contralateral ear of these cases in which the hearing improved only in an unilateral ear showed total deafness or was almost totally deaf.
6. In immunoglobulin tests IgM was found abnormal in three cases, IgA and IgG were abnormal in two cases respectively In two cases, the blood sedimentation rate was elevated when the patient noticed the hearing deterioration.
7. It was confirmed that there existed SNHL which responded to steroid hormore among cases with acute hearing deterioration. For the cases improved by steroid administration or steroid readministration on recurrent hearing deterioration, autoimmune SNHL should be suspected and further immunological examinations should be done.
8. By the long-term administration of steroid to steroid-responsive SNHL, it was shown that hearing deterioration could be prevented and the hearing level before treatment could be maintained.抄録全体を表示PDF形式でダウンロード (934K) -
大内 利昭, 神崎 仁, 岡田 拓治, 志賀 逸夫1982 年 28 巻 5Supplement3 号 p. 959-968
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーDepartment of Otolaryngology, School of Medicine, Keio University Department of Diagnostic Radiology, School of Medicine, Keio University Inner ear anomaly should be always taken into the consideration as one cause of sensorineural hearing loss of unknown etiology.
we investigated the clinical value of CT target imaging with 1.5mm slice thickness for the purpose of finding out the bony inner ear anomalies.
In this communication, we have reported the results of dimensional measurements of inner ear structures in 30 ears with normal hearing and described five cases of inner ear anomalies which were found by CT target imaging.
In this study, the dimensional measurements were performed in two kinds of projections; axial and coronal projections.
The results were as follows;
(1) The diameter of the porus of internal auditory canal is about 1.0mm bigger in anteroposterior plane (6.71mm) than in vertical plane (5.70mm).
(2) The length of the internal auditory canal is very variable in individual cases in both axial and coronal projections compared with the other parameters of inner ear structures.
(3) The long axis of bony vestibule (6.49mm) is about 2.3 times large compared with the short axis (2.83mm) in axial projection.
(4) The obtained diameter of the short axis of bony vestibule (2.83mm) in axial projection is about the same as the diameter of the transveres axis (2.93mm) in coronal projection.
(5) The obtained diameter from the inner wall of the vestibule to the most lateral part of the lateral semicircular canal is about the same in both axial projection (4.82mm) and coronal projection (4.47mm).
(6) The distance between the lateral semicircular canal and the posterior semicircular canal in axial projection is about 2.40mm.
(7) When the obtained values of dimensional measurements of inner ear structures were compared between the ears with normal hearing and ears with sensorineural hearing loss, the CT target imaging with 1.5mm slice thickness seems to be very useful for finding out the inner ear anomaly which is one cause of the sensorineural hearing loss of unknown etiology.抄録全体を表示PDF形式でダウンロード (10147K) -
難聴の進行について西端 慎一, 岡本 牧人, 設楽 哲也1982 年 28 巻 5Supplement3 号 p. 969-975
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーThirty-three cases with progressive sensorineural hearing loss of unknown etiogy were studied. Twenty-four cases were bilateral and others were unilateral.
The results were summarized as follow.
1) The distribution curve of patient against age shows twod peaks, one was 0 to 10s and the other was 30s to 60s.
2) The rate of hearing impairment of the progression type was about 1dB/ month.
3) The unilateral type showed greater hearing loss in high frequency than the bilateral type.抄録全体を表示PDF形式でダウンロード (700K) -
藤野 明人, 岡本 牧人, 設楽 哲也, 小田 恂1982 年 28 巻 5Supplement3 号 p. 976-982
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーIn 221 patients with sudden deafness, who came to our hospital within 2 weeks after the onset, herpes simplex virus (HSV) complement fixation (CF) test was performed. Forty six percent of these cases showed positive CF antibody and it was statistically significant against normal control data.
The paired serum tests were performed in 98 cases. Significant changes of CF antibody titers were found in 10 cases (10.2%) of these 98 cases.
In these particular cases, HSV was suspected as one of the causative factors of sudden deafness.
Clinically, no apparent differences were observed between sudden deafness caused by HSV and that by other causes.抄録全体を表示PDF形式でダウンロード (723K) -
岡本 牧人, 設楽 哲也, 小田 慎, 西端 慎一1982 年 28 巻 5Supplement3 号 p. 983-989
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーFive Patients with Behcet's disease who suffered from sensorineural hearing loss were followed by measuring the audiologic examinations. Their hearing thresholds became worse with/without fluctuation during the followup-period from six months to four years and eight months. After the detailed audiologic examinations, the inner ear lesion was mostly suspected in each case. Tinnitus or high tone hearing loss was observed in four cases as an initial ear symptome, and in some cases hearing loss was appeared suddenly like as the sudden deafness. Contralateral side was also involved in their clinical course in four cases. Corticosteroid therapy was effective in the acute attack of hearing loss.抄録全体を表示PDF形式でダウンロード (713K) -
その基礎的諸要件伊藤 明和, 鈴木 康之, 鈴木 浩二, 中島 務, 渡辺 祐介, 三宅 弘1982 年 28 巻 5Supplement3 号 p. 990-1000
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーIt is intended to clear the conditions of inner ear circulation through the fundamental research of inner ear circulatory system, as well as the study mainly on the cases of circulatory disturbance, especially insufficiency of blood pressure, clinically.
The outline is as follows. Namely, in the inner ear the presence of sympathic control was presumed with predominance in a-effect. Further, through the study of CO2 and anoxia influencing the oxygen partial tension of inner ear fiuid, inner ear blood flow, inner ear pressure, oxygen partial tension of cerebrospinal fluid, cerebral blood flow and cerebrospinal fluid pressure, it has been noted that the reaction pattern in the inner ear is roughly fairly similar to that in the brain. In addition, the inner ear pressure and blood flow were fouud to be closely related to the variation of cerebrozpinal fluid pressure via the total blood pressure, inner ear blood pressure or cochlear aqueduct, from the reaction anode of perilymphatic pressureunder the load of anoxia, as well as the findings of inner ear blood flow, EP, etc. in case the inner ear pressure was increased artificially. The influences of glycerol and other diuretics on the inner ear blood flow and inner ear oxygen tension were observed from the point of rupture of the round window, and the blood vessel and blood flow of the inner ear were obsrved through the round window. In addition, various findings were obtained about the inner ear circulation.
As clinical research, the results of animal experiment on the oxygen tension of innr eare fluid and and blood flow of inner ear may not be applied directly in the clinic, but it has been suggested that the tendency of hearing variation is influenced strongly by the inner ear blood vessel, total blood pressure and cardiac output.抄録全体を表示PDF形式でダウンロード (1734K) -
臨床例及び実験成績柳田 則之, 坂堂 正生, 横井 久, 三宅 弘1982 年 28 巻 5Supplement3 号 p. 1001-1009
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーAcute sensorineural deafness was studied in 5 cases caused by sudden change in atmospheric pressure.
It was bilateral only 1 case, appearing while flying in a helicopter. In the other 4 cases it was unilateral, caused by diving in 3 cases, and the remaining case had slight damage at diving, and then aggravated by flying.
All these 5 cases had diving or glying not only once, but often since before.
They had various degrees of hearing loss, but all flat form deafness, recruitment (-i-) and TD (-). Vestibular symptoms were not present, and hearing recovery can be expected fully at early period.
As the causes of inner ear disorder, labyrinth window membrane rupture and vascular disturbance in the inner ear are mentioned, but according to our experiment with guinea pigs, at the time of sudden change in pressure is beyond adjusting capacity of the auditory tube, the change in pressure is transmitted directly to the inner ear via the labyrinth window membranes, giving a strong impulse mainly to the basilar and Reissner's membranes to damage the Corti's organ.抄録全体を表示PDF形式でダウンロード (3333K) -
実験的中枢変性症における聴覚系への影響稲福 繁, 瀧本 勲, 犬塚 一男, 江夏 努, 杉山 貴志子, 森本 高弘, 川出 博彦, 大島 瑞代, 原 誠彦, 吉川 兼人1982 年 28 巻 5Supplement3 号 p. 1010-1017
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーA chronic relapsing form of allergic encephalomyelitis and neuritis which was characterized in man was induced experimentaly by single sensitization of immature and adult Hartley guinea pigs. Among them, a few animals showed a severe hearing loss. Histological studies of their cochlea showed a severe loss of ganglion cells and hair cells. The organ of Corti was atrophied but Stria vascularis had no changes. There was granular precipitate in Scala media and Scala tympani. Thus there may be possibilities that the chronic encephalomyelitis could affect the inner ear as the results of our experimentes. The sensorineural hearing loss with unknown etiology may be considered to some immunologic diseases.抄録全体を表示PDF形式でダウンロード (8027K) -
森川 美子, 瀧本 勲1982 年 28 巻 5Supplement3 号 p. 1018-1025
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーThe cases with sensorineural hearing loss from 1978 to 1980 were reported. The cases content: sudden deafness 37 cases, fluctuating hearing loss 6 cases, progressive hearing loss 6 cases, unilateral hearing loss 65 cases, sensorineural hearing loss with internal diseases 328 cases.
In the cases with internal diseases, we could trace 94 cases during 1-3 years, and they were classified following items of the group of internal diseases, age, sex, degree and type of hearing loss. The group of internal diseases contained central nervous system, respiratory, digestive, cardiovascular and renal, hematogenous, endocrine and immune diseases.
So we have not enough cases, we couldn't detect any correlation between the changes of the internal diseases and sensorineural hearing loss. The further studies should be required.抄録全体を表示PDF形式でダウンロード (752K) -
高橋 昭, 佐橋 功, 祖父江 元, 五藤 進一朗, 中尾 直樹, 藤井 勝朗, 木原 幹洋, 村上 研, 土屋 一郎, 瀧本 勲, 稲福 ...1982 年 28 巻 5Supplement3 号 p. 1026-1043
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーA description is given of 6 cases of impaired hearing function coexisting with generalized neuromuscular involvement, encounted out of a total of 288 hospital patients in the neurological clinic during 1981. These included acute mixed polyradiculitis (38 year-old female), familial polyneuropthy probably of Rosenberg-Chutorian type (siblings of 20 year-old brother and 24 year-old sister), chronic progressive polyneuropathy of predominantly sensory type (57 year-old male), acrocephalosyndactyly (16 year-old female), and myopathy akin to Kearns-Shy syndrome with hypo-TBG-emia (58 year-old female).
In addition to the preceding report, the following results were obtained:
(1) Impaired hearing loss of sensori-neural type may occur in association with a variety of generalized neuro-muscular diseases.
(2) Hearing loss as an initial symptom may precede and be followed by the remaining neurological deficits.
(3) Hearing loss is variable, ranging from mild high-frequency loss to profound deafness. Occasionally audition is almost normal in one ear.
(4) The mode of onset of hearing loss may be relatively acute or subacute in some cases, though the underlying illness was of insidious onset or of slowly progressive course.
(5) Hearing loss is detected even in some cases without complaint.
(6) There exists a significant relation between sensorineural hearing loss and decreased vibratory sensation in the extremities.
(7) There were some clinical evidences suggesting the brainstem lesion along with that of the peripheral cohlear nerve.抄録全体を表示PDF形式でダウンロード (7285K) -
村田 清高, 西前 忠英, 太田 文彦1982 年 28 巻 5Supplement3 号 p. 1044-1051
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーEighteen ears of 14 patients developed sensorineural hearing loss associated with (A) pregnancy,(B) delivery,(C) puerperium,(D) menstruation and (E) administration of female hormones.
Audiological examination revealed the following clinical aspects. 1) Hearing loss in (A),(B) and (C) occurred in the twenties and early in the thirties.
2) Acute hearing loss of 9 ears showed unilateral, abrupt onset like sudden deafness. Sudden impairment of hearing occurred in pregnancy, immediately after delivery and in administration of progesterone and/or estrogen.
3) Slowly progressed hearing loss of 4 ears developed bilaterally in puerperium or periodically in menstruation.
4) Audiograms of (A),(B) and (C) showed high tone loss in most cases. Hearing impairment was slight or severe.
5) Audiograms of (D) and (E) showed hearing loss of flat type. Hearing loss was moderate.
6) Békésy audiogram showed type II configuration, SISI score revealed mostly positive.
7) Pure tone audiograms of acute hearing loss were significantly improved, however restoration of slowly progressed impairment was poor.
Effects of progesterone and estrogen on hearing loss were discussed in order to explain pathogenesis of these hearing impairments.
It seemed unreasonable to regard the disease merely as side effects of female hormones.抄録全体を表示PDF形式でダウンロード (1076K) -
聴覚系の周波数特性を考慮した語音聴取能検査法の応用細井 裕司, 今泉 敏, 阿部 博香, 玉木 克彦, 太田 文彦1982 年 28 巻 5Supplement3 号 p. 1052-1058
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーSome audiological examinations, by such as Békésy's self-recording audiometry, DLSI test, speech audiometry etc., have been carried out in cases with audiograms of so called sharp cut configuration. Speech audiometry was performed by means of our new method published in Audiology Japan (1980, 1981). Steep incline portion of each audiogram was carefully examined by Békésy's audiometer which have dumping ratio of 5dB/sec. and sweep ratio of 0.5 octave/min.
The DLSI (Difference limen for short increment) values obtained from these cases remained within 1.8dB. Speech discrimination scores of the patients, examined by our new method, revealed no characteristics of retrocochlear lesions. In conclusion, neither DLSI values nor speech discrimination scores by our new method suggested retrocochlear lesions.抄録全体を表示PDF形式でダウンロード (840K) -
宮前 雅明, 玉木 克彦, 西本 力, 中西 理恵子, 太田 文彦1982 年 28 巻 5Supplement3 号 p. 1059-1067
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーTwo hundred cases of sudden deafness confirmed the date of onset were investigated. In 98 cases out of them, sudden deafness attacked during prevalent seasons of rubella in Osaka; 1976-1977 and 1981-1982. Forty-two patients out of them with higher antibody titer against rubella virus than 16 showed profound hearing loss. Restoration of hearing in these cases was significantly poor in compared with the other patients group.抄録全体を表示PDF形式でダウンロード (795K) -
平島 健二郎, 中島 恒彦, 朝隈 真一郎, 伊藤 正博, 鳥谷 陽一, 村塚 幸穂, 沖 勉1982 年 28 巻 5Supplement3 号 p. 1068-1073
発行日: 1982/12/01
公開日: 2013/05/10
ジャーナル フリーIt has been well known that some of the patients complaining tinnitus has no hearing disorders. Based on our clinical studies we tried to get a clue of the cause of tinnitus in normal hearing persons. In this paper three possibil ities as the cause of it are proposed.
1) There may be some hearing disorders which can't be detected with usual pure tone audiometry.
2) In the soundproof room we feel a kind of tinnitus, which may be exaggerate with psychological factors in some patients.
3) Objective tinnitus can be one of causes of it.抄録全体を表示PDF形式でダウンロード (675K)
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