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Volume 43, Issue 5
Displaying 1-15 of 15 articles from this issue
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Manami TAKAMATSU, Sei KITAJIMA, Shinya TAKANO, Hajime ARAMAKI, Ichiro ...1997 Volume 43 Issue 5 Pages 579-583
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSIn most blow-out fracture cases, otorhinolaryngologists perform surgery using the antral balloon techniqe to keep the balloon in the correct position of the sinus. The use of a rigid endoscopic telescope with an external incision was found to help in the reconstruction of a blow-out fracture of the medial orbital walls.
An external reconstruction was thus performed in 2 cases of a blow-out fracture of the medial and inferior orbital walls under general anesthesia. The results of this surgical technique proved to be good in all cases, however, a high degree of technical skill is required.View full abstractDownload PDF (10151K) -
Osamu YADOHISA, Shizuo KOMUNE, Takashi KIMITUKI, Hiroshi KAWAGUCHI, Na ...1997 Volume 43 Issue 5 Pages 584-589
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA 42-year-old woman with bilateral otoscrelosis underwent an operation on her right ear. An interesting finding was that all the ossicles were fixed and demonstrated otosclerotic lesion in a pathological study. At the first operation, a malleus head and short process of incus were found to be fixed to the inside wall of the epitympanic space and therefore had to be seperated from the inner wall of the epitympnic space. A teflon piston measuring (0.3×3.5mm in diameter) was thus placed between the long process of the incuss and the oval window after stapedectomy. However, the patient's hearing did notimproved. At the second operation both the malleus head and incus was found to have again become refixed. The incus and head of malleus were thus removed. A teflon piston was then again placed between the chorda tympani nerve and oval window. After the operation, the patient's hearing improved. A pathological examination revealed all the ossicles to be the result of otosclerosis.View full abstractDownload PDF (11816K) -
Masafumi NAKAGAWA, Hiroyuki TAKEZAWA, Masako WATANABE, Ryoukichi IMAI, ...1997 Volume 43 Issue 5 Pages 590-593
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA case of basal cell adenocarcinoma of the submandibular gland is reported. The patient was a 7-month pregnant 25-year-old female who presented with a painless mass in the right submandibular gland area. In her past history she had previously noticed a swelling in the same area and had undergone biopsied at another hospital 4 years previously. A histological examination indicated her normal salivary glands to have no tumorous lesion. After a natural delivery the patient underwent a surgical excision and the histological diagnosis was basal cell adenoma.
18 months later, the tumor reccurred in the same area. At this time she was at again 7 months pregnant. A surgical excision was again performed after the second delivery. This histological diagnosis was basal cell adenoma, with a suspected infiltration to the musle structures. 6 months later the tumor once again reccurred locally and thus was immediately surgically removed. Histopathologically, the tumor cells were extended infiltrated to the adjacent tissues, and were diagnosed as basal cell adenocarcinoma. The patient underwent postoperative radiotherapy with 50Gy and there has since been no sign of either local reccurence or metastasis for 18 months.View full abstractDownload PDF (8538K) -
Yorikazu TOYOZUMI, Toshimi MIYAZAKI, Minoru HIRANO, Takao MITUMASU1997 Volume 43 Issue 5 Pages 594-607
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSIt is traditionally thought that laryngeal muscles evolved from the M. laryngeus ventralis et dorsalis to the laryngeal muscles of the human larynx. However, based on our investigation of bullfrogs, trionychidae and domestic fowl (hens), we did not observe such muscles but instead observed different muscles. Our findings thus suggest that there is no direct evolution of the laryngeal muscles from lungfish to mammals. Study method
The laryngeal muscles excluding the extrinsic muscles of the bullfrog, trionychidae and domestic fowl (hens) were next comparatively analyzed under a binocular microscope after the larynx was removed. The results are summarized as follows
1. In all animals studied, fan shaped muscles were confirmed to be laryngeal muscles running in a direction from the front of the middle area of the arytenoid-cartilage on both sides.
2. According to the traditional theory, the Mm. laryngeus ventralis et dorsalis of the primitive laryngeal muscles evolved into the M. laryngeal muscles of the mammalia.
3. Based on our findings, the systematic evolution of the laryngeal muscles is thus considered to be as follows (except for the extrinsic muscle):
a) primitive type (lung-fish, primitive bullfrog type)Mm. laryngeus ventralis et dorsalis and M. sphincter larygnis (from Goeppet; fixer of theglottis)
b) transitional type (bullfrog, trionychidae and domestic fowl type) fan shaped laryngeal muscles (fixer of the glottis)
c) Mammal type-M. intrinsic laryngeal muscles (closer to theglottis)It was therefore concluded that the evolution of the laryngeal muscles progressed from primitive type (No.1) to transitional type (No.2) and finally reaching mammal type (No.3).View full abstractDownload PDF (22931K) -
An analysis based on the results of a cytodiagnosis of nasal secretionShinichiro ASAKUMA1997 Volume 43 Issue 5 Pages 608-613
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSRhinitis can basically be divided into two groups consisting of infectious rhinitis and allergic rhinitis groups. This is clinically important because the appropriate medication differs for the two groups. Many clinical tests for nasal allergies, for example the skin scratch test, RISA and RAST, may show us that the patient is sensitized with some antigens. However, such a finding dose not necessarily indicate that the rhinitis is caused by an allergic reaction. If nasal eosinophilia is found in the cytodiagnosis findings of nasal secretion, a nasal allergy is thus strongly suggested. From this point of view cytodiagnoses of nasal secretion were thus carried out on numerous rhinitis patients. The number of cytodiagnosis tend to increses in April whichi thus implies an increase rate of rhinitis patients in April. A cytodiagnosis shows that not only allergic rhinitis but also infectious rhinitis therefore appears to increase simultaneously.View full abstractDownload PDF (9661K) -
An early phase II studyMinoru OKUDA, Hiroshi TOMITA, Nobuo USUI, Akikatsu KATAURA, Kouji ASAK ...1997 Volume 43 Issue 5 Pages 614-630
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSTo examine the efficacy, safety and usefulness of ONO-1078 in patients with perennial allergic rhinitis due to house dust, a comparative study using the envelope method was conducted.
The total number of subjects was 64. These subjects were divided into a 150mg/day group (Group L, 33 patients) and a 450mg/day group (Group H, 31 patients).
Concerning the final global improvement rating, a moderate improvement or better was achieved in 48.4 % of the patients in Group L and in 60.7% of the patients in Group H. The rate of improvement was higher in Group H although the defference was not significant between the two groups. With respect to symptoms, ONO-1078 markedly improved the nasal congestion, in particular. In Group L, the rate of improvement in nasal congestion was 50.0% two weeks after the start of administration and 61.3% four weeks after the start of administration. In Group H, the rate was 69.0% and 73.1% two and four weeks after the start of administration, respectively. ONO-1078 inhibited the increased Nasal Airway Resistance (NAR) related to antigen induction. The nasal mucosal swelling improved in 50.0% of the patients 4 weeks after the start of drug administration. Concerning the ovevall safety rating, this drug was evaluated as safe in 90.9% of the patients in Group L and in 90.3% of the patients in Group H. The incidence of side effects was 9.1% in Group L and 9.7% in Group H. The degree of adverse experiences was mild in all patients. Either discontinuing drug administration or the completion of the full regimen resulted in the disappearance of all adverse experiences, however, no serious adverse experiences were observed. Concerning usefulness rating, the drug was evaluated as being useful in 43.8% of the patients in Group L and in 58.6% of the patients in Group H. This drug was thus more useful in Group H, although there was no significant difference between the two groups.
These findings thus suggest that ONO-1078 is effective for the treatment of perennial allergic rhinitis due to house dust, especially regarding the control of nasal congestion, and it can also be safety administered.View full abstractDownload PDF (29602K) -
A double-blind, dose finding study (late phase II study)Minoru OKUDA, Tokuji UNNO, Tetsuharu WADA, Yukio INUYAMA, Shiroh MAGUC ...1997 Volume 43 Issue 5 Pages 631-657
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSA multi-center, double-blind group-comparison study of ONO-1078 (pranlukast hydrate) was performed at 3 different doses to evaluate its efficacy, safety, and optimal dosage in patients with perennial nasal allergy.
A total of 198 subjects were enrolled in the study, and pranlukast was administered at 75mg/day to 66 subjects (Group L) at 225mg/day to 68 subjects (Group M) and at 450mg/day to 64 subjects (Group H).
The final global improvement rating was 44.8% in Group L, 46.7% in Group M and 64.3% in Group H. The rate was dose dependent and was significantly higher in Group H than in Group L. According to the nasal allergy diary, the three principal symptoms, namely sneezing, nasal secretion and nasal congestion, progressively and significantly decreased in all three groups, while the decreases in nasal secretion and nasal congestion were both significantly greater in Group H than in Group L. The overall safety rating was “safe” in 93.8% in Group L, 86.6% in Group M, and 88.5% in Group H, and adverse experiences were observed in 4.6% of Group L, 13.4% of Group M, and 11.5% in Group H, with no significant difference observed among the three groups. The usefulness rate was 44.1% in Group L, 45.9% in Group M, and 59.6% in Group H, and these findings were also dose-dependent.View full abstractDownload PDF (45841K) -
Masato YOKOYAMA, Natsuhiko MITOMI, Katsuhiko TEZUKA, Niro TAYAMA, Seij ...1997 Volume 43 Issue 5 Pages 661-665
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSSixteen asymptomatic volunteers (8 young and 8 elderly) and 8 elderly patients with pharyngo-laryngo-esophageal neuralgia (PLEN) were studied by manofluorography. Compared with the young, elderly volunteers results in a significant increase in the pharyngeal and oropharyngeal transit times. Transit time of upper esophageal sphincter (UES) was increased and UES preparatory time (duration of pre-bolus-arrival relaxation of UES) was decreased in the elderly volunteers compared with young group. Decrease of tongue motility and delay of UES relaxation by aging were suggested. In elderly patient with PLEN, bolus with high viscosity resulted in a significant decrease in the UES transit time, compared with barium and Conlay 60®View full abstractDownload PDF (8037K) -
Ibuki HAYASHI, Yoshiko HAYASHI, Isao UNO, Yuki FUJIWARA, Hiroaki TAKAH ...1997 Volume 43 Issue 5 Pages 666-672
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe submental surface electromyography (EMG) is considered non-invasive and effective technique to reveal the beginning of deglutition. However, it is not measured each muscular contraction directly. The purpose of this article is to compare the submental EMG with the muscular activities concerned with laryngeal elevation.
The subjects were five healthy young males aged 25-31 yr. The submental surface EMG and EMGs of the thyrohyoid and the geniohyoid muscles were concurrently recorded.
There were two changes on the wave of the submental EMG at deglutition. The former change had small amplitude and the latter had large amplitude. We define the onset of the former as EMG1 and the onset of the latter as EMG2.
EMG1 is most associated with the onset of the geniohyoid muscle activity. It shows that EMG1 is the beginning of the oral phase of the deglutition. EMG2 is most associated with the onset of the thyrohyoid muscle activity. It shows that EMG2 is the beginning of the pharyngeal phase of the deglutition. We conclude that the submental EMG is useful to reveal the onset of the oral and pharyngeal phases of deglutition.View full abstractDownload PDF (9242K) -
Yasushi SUZUKI, Mineko TSUCHIDA, Satoshi HORIGUCHI1997 Volume 43 Issue 5 Pages 673-679
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSIn this study we measured the maximum amount of bolus for one nomal swallow and defined the maximum swallowing as this amount of bolus. We examined the physiological significance of the maximum swallowing in two boluses of different viscositis.
A total of 24 non-dysphagic individuals were included in the study. Subjects were given trial volumes of water and 2% Throsoft S® (an aqueous solution of a starch powder) that were increased at 10ml intervals, and we measured volumes of bolus for one swallow to decide the maximum swallowing.
During the study we were able to determine the maximum swallowing of water for 15 subjects (63%), and of 2% Throsoft S® for 11 cases (46%). We noted that as viscosity increased the maximum swallow decreased. In some cases we observed as the trial volume exceeded the maximum swallowing the actual amount swallowed decreased. We are thus able to advocate the curve between the trial volume and the volume swallowed at one time.View full abstractDownload PDF (8664K) -
Atsushi KAWASAKI, Hiroyuki FUKUDA, Hideki NAKAGAWA, Jin KANZAKI1997 Volume 43 Issue 5 Pages 680-683
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSIt is well known that that the larynx has principally the protection of airway in addition to respiration and phonation.
In this study, we observed the movement of vocal folds during swallowing from the frontal plane and recorded videographically to evaluate and analyze the data obtained.
(Method)
Object: Healthy young adults
Contrast medium: one fifth diluted Omnipark 300
The volume of the medium for one swallowing: 15cc
System: The views from the frontal plane were observed with an X-ray fluorography and the images that had be recorded at 30 frames per second were subtructed by digital subtraction system. Then the images were captured into a personal computer and a frame-by-frame analysis was performed.
(Results)
The observations and analysis we have performed are summarized as follow.
1: We observed laryngeal closure from the frontal plane during swallowing.
2: The movement of vocal folds during swallowing was observed.
3: We observed that the closure of vocal fold level follows that of false vocal fold level and that vocal fold level opened first, then false vocal fold level.View full abstractDownload PDF (6519K) -
[in Japanese]1997 Volume 43 Issue 5 Pages 684-685
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSDownload PDF (3961K) -
Yukio OHMAE, Satoshi KITAHARA, Etuyo TAMURA, Masarni OGURA, Takehiro K ...1997 Volume 43 Issue 5 Pages 686-689
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSThe purpose of this study was to determine the effects and limitations of transcutaneous silicon injection on swallowing function in the unilateral vocal cord paralysis with aspiration. The preoperative and postoperative swallowing function were evaluated by mean of videofluoroscopy in ten patients who were performed silicon injection into the laryngeal vestibule, ventricle, vocal cord as a whole. Data analysis comparedl) types of aspiration and pharyngeal clearance, 2) timing of laryngeal closure. In eight of the 10 patients, a favorable clinical response was achieved after the silicon injection. Timing of laryngeal closure could be quantified in eight patients, and the timing was significantly earlier in seven patients. Pharyngeal clearance was improved in seven of the 10 patients. On the other hand, in two of the 10 patients, silicon injection produced the improvement of the timing on laryngeal closure, but pharyngeal clearance did not changed and aspiration have been observed on videofluoroscopy. These results suggested that silicon injection therapy produce useful effects on laryngeal closure and pharyngeal closure during the swallow, but there are limitation to prevent aspiration in individuals with the impairment of bolus propulsion and/or driving force.View full abstractDownload PDF (6846K) -
Hiroyuki YAMASHITA, Yuichiro KURATOMI, Yoshihiko KUMAMOTO, Tomoya YAMA ...1997 Volume 43 Issue 5 Pages 690-695
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSCricopharyngeal myotomy was applied to twenty-eight in-patient with dysphagia. Twenty-one (75%) patients were regarded as successful. No significant difference was observed between patients who underwent cricopharyngeal myotomy and patients who underwent cricopharyngeal myotomy and laryngeal suspension. Successful rate was best in laryngeal trauma and CVA (cereberovascular accident) followed. Two of four were free from dyspagia in patients with amyotrophic lateral sclerosis and one of two was free from dysphagia in patients with progressive bulbar palsy. Results in patients with thoracic disease were poor. One patient underwent total laryngectomy and another patient underwent closure of larynx. Results were satisfactory in patients under 65 years old, that is, twelve of thirteen (92%) were regarded as successful. However, results were unsatisfactory in patients over 65 years old, that is, only nine of fifteen (63 %) were regarded as successful. Significant difference was observed between two groups (p<0.05). Cricopharyngeal myotomy was less effective for patients over 65 years old.View full abstractDownload PDF (10473K) -
1997 Volume 43 Issue 5 Pages 696-701
Published: September 20, 1997
Released on J-STAGE: May 10, 2013
JOURNAL FREE ACCESSDownload PDF (7898K)
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