jibi to rinsho
Online ISSN : 2185-1034
Print ISSN : 0447-7227
ISSN-L : 0447-7227
Volume 48, Issue 6
Displaying 1-10 of 10 articles from this issue
  • Tomoyuki NAGAI
    2002 Volume 48 Issue 6 Pages 377-380
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    We herein demonstrate that the inflow of mucin into the lymphatic vessels causes lymphedema resulting in inflammation of the cholesteatoma perimatrix. The mucous epithelium in the mastoid cavity must communicate with the middle ear cavity, and therefore the intact canal wall technique is the best method for performing cholesteatoma surgery. If a reconstruction of the auditory meatus or an obliteration of the mastoid cavity is planned, then rich blood supplied pedicle flaps such as the temporalis fascia must be used. Seven cases of middle ear cholesteatoma with an open cavity were operated on using the vascularized temporalis fascia flap. The auditory meatus was either reconstructed or the mastoid cavity was obliterated in these cases. The anterior tympanic route was used for aeration of the mastoid cavity for a reconstruction of the auditory meatus. The surgical procedures successfully relieved the symptoms of cholesteatoma, ear discharge and vertigo in all patients.
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  • Noboru SAKAI, Takehiko KOKUBUN, Ken-ichi KOICHI, Yoshihiko TERAYAMA
    2002 Volume 48 Issue 6 Pages 381-384
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    We have recently developed a new measuring method using fine materials during ear surgery. This method uses sliced silicon mesh fragments to easily and accurately measure various things in the narrow operating field of ear surgery. We herein describe our experience in measuring ear-drum perforations, grafts for myringoplasty, tympanomeatal flaps, defects in the ossicular chain, reconstruction materials and Teflon wire pistons. This measurement method is also applicable to laryngeal surgery as well as ear surgery and is expected to become increasingly more popular in the future.
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  • Shinichiro ASAKUMA
    2002 Volume 48 Issue 6 Pages 385-390
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Three hundred and eighty-four patients with acute low-tone sensorineural hearing loss (ALSH) who consulted my clinic from 1987 to 2001 are herein retrospectively investigated. The results are as follows. 1) In 1999, I reported that the number of ALSH patients had gradually increased from 1987 to 1996. This tendency continued from 1997 to 2001.2) The number of female patients continued to increase while, on the otherhand, the number of male patients showed no significant increase. 3) Of the 212 patients, 81.1% and 6.6% showed a complete and partial recovery of hearing, respectively. 4) Aetiologically, ALSH may be due to a dysfunction in either the autonomic nervous system or a hormone inbalance in the patients probably caused by some type of social anxiety. 5) Comparing the therapeutic effects of yoryzanol, isosorbide and steroids on ALSH, yoryzanol showed the best results. 6) The patients whose hearing level in high frequency regions decreased tended to show a poor recovery. 7) Recently, the recovery rate of ALSH is gradually declining. This is considered to be due to the increase in the number of patients whose hearing levels in high frequency regions decreased.
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  • Naoko MATSUBARA, Toshiro UMEZAKI, Kazuo ADACHI, Kouji KOIKE, Naoya HIR ...
    2002 Volume 48 Issue 6 Pages 391-396
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Laryngeal necrosis occurs rarely after radiation therapy for laryngeal cancer. We performed radiation therapy with a total dose of 68.2Gy on a 61-year-old man, whose larynx revealed partial necrosis two months later. Thyroid cartilage was exposed from the inside of the larynx and a piece of cartilage was also destroyed. We performed laryngomicrosurgery to remove the necrotic tissue and to confirm that there was no residual cancer. We administered clarithromycin and beraprost sodium for 102 days. Beraprost sodium is the first orally active prostacyclin analogue, and it has various biological activities including a vasodilation effect and a cytoprotective effect on endothelial cells. As a result, the inside of the larynx was covered by a healthy mucosa six months after radiation therapy. We cured the laryngeal necrosis without using steroids and thus were able to successfully preserve the function of the larynx.
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  • Nobusuke HOUCHI, Masafumi YOSHIDA, Tsuyoshi UDAKA, Nobuaki HIRAKI, Gun ...
    2002 Volume 48 Issue 6 Pages 397-403
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    Fifty-eight patients with hypopharyngeal carcinoma, who were treated at our hospital (UOEH) from 1990 to 1999, were retrospectively analyzed regarding the treatment modalities and survival. Following induction chemotherapy (CBDCA+5-FU), 36 operable cases underwent surgery (with or without a total- laryngectomy) and/or radiation therapy and 22 inoperable cases received 2 courses of chemotherapy followed by radiation therapy. The overall 5-year survival rate was 35.3% for all patients, 70% for stage I (n=2) and stage 11 (n=8), 25% for stagal (n=12), and 28.3% for stage IV (n=36). In 10 patients whose larynx was preserved because of a successful response to the induction chemotherapy, 8 cases survived more than 3 years without recurrence, and only one case died due to local failure. A more effective induction treatment such as a combination of chemotherapy and radiation were thought to make larygeal preservation possible in patients with early stage disease. Of 26 patients who underwent surgery including a total laryngectomy, 11 cases had postoperative radiation therapy (30 to 70Gy) because their surgical margin was not sufficient. The 5-year survival rate for the radiation group was 63.3%, while the rate for the non-radiation group was 31.3%. These results indicated that postoperative radiation therapy should therefore be performed in all patients with hypopharyngeal carcinoma even after undergoing successful surgery.
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  • A high blood flow of the external carotid artery due to internal carotid artery stenosis
    Kyoichi TERAO, Kazunori MORI, Keisuke URANO, Takeshi KUSUNOKI, Masahir ...
    2002 Volume 48 Issue 6 Pages 404-407
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    We herein report the findings of a 74-year-old male with intractable epistaxis. The bleeding point was unknown and epistaxis could not be controlled by conventional packing and Bellocq's tampon method. MR angiography revealed a low blood flow in the left internal carotid artery (ICA). Angiography by Seldinger's procedure revealed 99% stenosis of the left ICA and a moderate blush of the sphenopalatine artery. We consider the cause of intractable epistaxis to be a high blood flow of the external carotid artery due to ICA stenosis. We performed a selective embolization of the sphenopalatine artery using a coil and the treatment was successful. No recurrent epistaxis has been observed in the patient for 1 year. Selective intraarterial embolization is thus considered to be an effective therapy for intractable severe epistaxis.
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  • Takumi OKUDA, Hirokazu KAWANO, Tetsuya TONO, Shizuo KOMUNE, Tadahide S ...
    2002 Volume 48 Issue 6 Pages 408-411
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    A 74-year-old female with malignant melanoma of the nasal cavity and no metastasis was treated with combination therapy consisting of local injections of interferon-β and radiotherapy. The treatment resulted in a remarkable decrease in the size of the tumor. After 15 intranasal injections of interferon-β, the nasal cavity tumor completely disappeared. She had no serious side effects during the treatment. Although local recurrence occurred one month after the initial treatment, it disappeared after local injections of interferon-β. The patient has demonstrated no recurrence for 2 years after the initial treatment. Taking the patient's quality of life into consideration, the combination therapy which we used is therefore considered to be useful for the treatment of malignant melanoma. In addition, local injections of interferon-β are also considered useful for the control of local recurrence.
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  • Kimihiro OHKUBO, Ryuta TAKIZAWA, Tokunari RAI, Sanae SHIMADA, Shunkich ...
    2002 Volume 48 Issue 6 Pages 412-420
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    The efficacy of combination therapy consisting of anti-histamine and anti-leukotriene drugs was compared with the monotherapy of each drug for Japanese Cedar Pollinosis patients. Fifty-one patients were randomized into 3 groups: cetirizine 10mg once a day, planlukast 225mg twice a day, or the combination of both, for more than 6 weeks during the pollen season of 2000. The symptom score, medication score and the symptom-medication score were calculated based on the daily symptoms which the patients recorded in diaries. The nasal symptoms improved in all groups, but no synergic effect of the combination therapy was observed in this study. Additional studies are required to confirm the usefulness of this combination therapy using anti-histamine and anti-leukotriene drugs for the treatment of seasonal allergic rhinitis.
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  • Satoshi OGINO, Noriaki TAKEDA, Tamotsu HARADA, Katsuhiko NAKAMURA, Koi ...
    2002 Volume 48 Issue 6 Pages 421-431
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    The effectiveness of cetirizine prophylactic treatment for patients with Japanese cedar pollinosis was investigated by measuring the nasal symptom score during peak pollen exposure speriods. This study was performed in at least 3 areas in Japan: Osaka, Tokushima and Okayama for 2 weeks from March 5 to 19, 2001, and the self-evaluated nasal symptom scores were measured. Patients who had been taking cetirizine 10mg once daily prior to entering the study were classified as the treated group, and patients without any previous treatments were classified as the non-treated group. A total of 73 patients from treated group and 210 from the non-treated group were thus analyzed in this study. According to the findings, all nasal symptom scores measured for the treated group (including sneezing, nose blows, nasal obstruction, interference with daily living, and the symptoms compared to the previous year) showed significantly less symptom severity than the non-treated group. These results showed cetirizine prophylactic treatment for Japanese cedar pollinosis to be effective for improving nasal symptoms.
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  • A follow-up study using a scoring system
    Yusuke ABE, Miki TAKAHARA, Isamu KUNIBE, Nobuyuki BANDOU, Ryo OHOTA, H ...
    2002 Volume 48 Issue 6 Pages 432-438
    Published: November 20, 2002
    Released on J-STAGE: May 10, 2013
    JOURNAL FREE ACCESS
    We conducted a follow-up study using a scoring system consisted of tonsil findings and clinical symptoms in order to compare the clinical efficacy of levofloxacin (300mg/day divided into 3 daily doses) for 7 days with that of amoxicillin (750mg/day divided into 3 daily doses) for 7 days in 30 adults with acute tonsillitis. After 8 days, the overall clinical score and score in the tonsil findings of the levofloxacin-treated patients were significantly lower than that of the amoxicillin-tereated patients (p=0.04, p=0.04 ; Mann-Whitney U-test). These results indicate that levofloxacin is an effective treatment which results in an earlier improvement in the tonsil findings. In addition, we also analyzed the relationship between the bacteriological investigations and the clinical scores. These results suggest that the presence of beta-hemolytic streptococcus is associated with more severe symptoms and a prolongation of this disease.
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