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Volume 102, Issue 11
Displaying 1-8 of 8 articles from this issue
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Hirotaka Ito, Shigeru Takagi, Yoshihisa Nakamura, Jo Nishimura, Motohi ...1999 Volume 102 Issue 11 Pages 1221-1226
Published: November 20, 1999
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSMany have reported on the effectiveness of laser surgery therapy for perennial allergic rhinitis. However, the suppressive effects of laser irradiation on allergic rhinitis and its symptoms have not been reported in patients with pollinosis. This is because therapeutic effects on pollinosis are difficult to evaluate. The amount of pollen in the air varies during the year, and from year to year. Also, allergic symptoms develop due to exposure to the amount of pollen which is markedly influenced by the weather. In this study, the severity of allergic symptoms in the pollen season was compared between patients treated with early medication, non-treated patients and patients treated with preseasonal contact Nd: YAG laser surgery.
Results suggests that laser surgery was effective in reducing the severity of symptoms in patients with cedar pollinosis. Symptoms were milder in the laser group than in the medication group and non-treated group for 3-4 weeks after the start of seasonal pollinosis, although no differences were noted in the early weeks. This may be explained by the fact that laser irradiation reduces the lamina propria of the nasal mucosa, the site of allergic reactions. This also suggests that allergic pollen can't penetrate the mucosal surface which shows squamous epithelization after laser irradiation.View full abstractDownload PDF (530K) -
Hiroshi Iwai, Toshio Yamashita, Masahiko Izumikawa, Toshiyuki Tsutsumi ...1999 Volume 102 Issue 11 Pages 1227-1233
Published: November 20, 1999
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSA retrospective study is presented comparing the results of 167 frozen section diagnoses of surgical extirpated parotid gland tumors with permanent-section diagnoses. Percentages of correct diagnosis for malignancy (cases correctly classified as benign or malignant tumors) and of correct diagnosis for histopathology (cases in which frozen section diagnosis and permanent-section diagnosis were identical) were calculated. Percentages of correct diagnosis for malignancy in all cases, benign cases, and malignant cases were 98.8%, 99.3%, and 95.8%, respectively. Percentages of correct diagnosis for histopathology in all cases, benign cases, and malignant cases were 94.0%, 97.2%, and 75.0%, respectively. These results are superior to the previous reports both of frozen section diagnosis and of fine-needle aspiration biopsy diagnosis although the data for histopathological diagnosis in malignant tumors are average compared to previous reports. We conclude that diagnoses of most parotid gland tumors based on frozen section examination are reliable and accurate, but caution should be exercised in malignant tumors diagnosis.View full abstractDownload PDF (4305K) -
Michiya Matsumura, Eiji Chida, Masaaki Kashiwamura, Satoshi Fukuda, No ...1999 Volume 102 Issue 11 Pages 1234-1241
Published: November 20, 1999
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSTransient evoked otoacoustic emissions (TEOAEs) were measured and evaluated in 194 ears of 101 subjects under 4 years old who were suspected of hearing loss, using a ILO88 Otoacoustic Emission Analyzer, to study the basic characteristics of this measure and its utility for hearing screening. The mean time necessary to record TEOAEs in both ears was short, about 3 minutes. In 58 ears judged as normal hearing within 30 dB in ABR, TEOAE levels in infants aged less than 2 months were significantly higher than in those aged more than 1 year, especially in the high-frequency bands (4-kHz and 5-kHz bands). One case which had been judged as bilateral moderate-toprofound hearing impairment in initial ABR testing showed good responses in TEOAEs, indicating normal cochlear function, and obvious wave Vs in follow-up ABRs recorded at 30 dB nHL confirmed normal auditory function. Therefore, in a case like this one, suspected of retardation in brain stem maturation, TEOAE is more useful than ABR as a hearing screening technique. Since external and middle-ear factors caused poor TEOAE responses in some cases which had been judged as normal hearing by ABR, TEOAE seems to be more sensitive in detecting external and middle ear problems than ABR. Moreover, TEOAE measurement of infants was easy and noninvasive. We conclude that TEOAE is an excellent tool for screening auditory function in infants.View full abstractDownload PDF (697K) -
Chihiro Hatta, Hiroshi Ogasawara, Masakazu Tsuyu, Jun Okita, Masafumi ...1999 Volume 102 Issue 11 Pages 1242-1248
Published: November 20, 1999
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSBetween 1986 and 1997, 72 patients (47 males, 25 females) with previously untreated tongue cancer were treated at our institution (surgery: 67, interstitial radiotherapy: 3, palliative therapy: 2). These patients, especially T2 tongue cancer, were classified into two groups (early T2: ≤3cm, late T2: >3cm) according to the maximum diameter of the primary lesion, and were analyzed for treatment outcome and cervical lymphnode metastasis.
(1) The cumulative 5-year survival rates were 65.9% for all cases, 95.0% for T1 cases, 77.5% (94.1% for early T2, 59.7% for late T2) for T2 cases, 24.3% for T3 cases (4-year survival rate), and 0% for T4 cases.
(2) The cumulative 5-year survival rates were 90.8% for pN-patients and 21.7% for pN+ patients and the difference was statistically significant (p<0.05%). In prognosis, pN- patients were better than pN+ patients. Since the N factor was related to the cause of death in 87.5% (7/8) of T2 tongue cancer, control of regional lymph node involvement was the most important prognostic factor.
(3) The overall incidence of cervical lymph node metastasis (pN+ or secondary nodal metastasis) was 35.3% for early T2 and 750% for late T2. The control rate of secondary nodal metastasis was 75.0% for early T2 and 33.3% for late T2.
Partial glossectomy only (observation for occult lymphnode metastasis) is recommended for treatment of T2N0, whereas glossectomy with selective neck dessection by the pull-through method is recommended for treatment of late T2.View full abstractDownload PDF (550K) -
Hiroe Miyasaka1999 Volume 102 Issue 11 Pages 1249-1257
Published: November 20, 1999
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSSevere sesorineural deafness develops occasionally after tympanoplasty. Since a vibration induced by the drill during surgery is thought to be one of the cause, we examined its effect on the inner ear in this study.
Five guinea pigs aged about 1 month were used. The right ear of each animal was used as the control, and the left ear underwent stimulation with the drill-induced vibration. The vibration was applied to the temporal bone for 60 seconds using a cutting bur. After the vibration, the stria vascularis and hair cells in the cochlea were examined. For the investigation of the permeability of the stria vascularis, horseradish peroxidase (HRP) was injected intravenously as a tracer, and the tissue was observed with a light and an electron microscopes. Three sections of the stria vascularis from each of the superior turn (the third turn) and the inferior turn (the basal turn) of bilateral cochleae were randomly prepared, and they were classified into Types I to IV according to the degree of HRP leakage. When a hair cell had even one vacuole inside, it was classified as a vacuole-positive cell.
After stimulation with the drill-induced vibration, about 10% of the blood vessels of the stria vascularis showed severe leakage of HRP (Types III, IV). In the intermediate cells, partial degeneration of mitochondria was found. No significant difference in the permeability of the blood vessels was found between the turns. The route of leakage of HRP from blood vessels of the stria vascularis was neither the transport via pinocytotic vesicle nor passage through the intercellular space of endothelial cells. The leakage through a tubular-like structure in the endothelial cells was observed. Since no HRP was found in this tubular-like structure ordinarily, a channel might have been opened by injury due to the vibration. The leakage from the blood vessels of the stria vascularis in the control side could scarcely be observed. Many hair cells in the drill-stimulaion side in both the first and the third turns showed vacuoles with loss of intracellular structure. Slight loss of auditory hairs was found in this study, suggesting that the development of a vacuole was the first reaction to the drill-stimulation. Since the sensitivity toward stimulation of the drill-induced vibration was different among individual animals, it appears possible that the inner ear is injured in some cases without direct touch to the auditory ossicles owing to technical failure.View full abstractDownload PDF (10425K) -
Kiyoto Shiga, Masaru Tateda, Jyunkichi Yokoyama, Shigeru Saijo1999 Volume 102 Issue 11 Pages 1258-1261
Published: November 20, 1999
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSWe report an adult case of asymptomatic congenital tracheal stenosis. A 42-year-old woman was admitted to our hospital, whose chief complaint was tongue pain. Clinical examination revealed a tumor 35×20mm in diameter along the middle, right edge of the tongue, and histopathological examination determined a diagnosis of squamous cell carcinoma of the tongue. She had no history of dyspnea, stridor nor recurrent pneumonia, and enjoyed playing table tennis in her daily life. Physical examination, electrocardiogram, spirogram and laboratory data showed no abnormal signs although chest roentgenogram revealed a narrowed trachea 6mm in diameter, however, the tracheal stenosis was not noted at the time. On the 10th hospital day, radical operation for cancer of the tongue including right hemiglossectomy and supraomohyoid neck dissection, were performed. Oral intubation was not successful, and a tracheostomy was conducted. The trachea was incised, and revealed that complete tracheal rings existed without posterior membraneous tissue. The operation time was limited because of high airway pressure for a narrow tracheal tube (5mm in diameter). The main postoperative complication was one crust formation in the tracheal lumen that resulted in CO2 narcosis due to check valve obstruction of the trachea on the 4th postoperative day. A nebulizer provided continuous moisture and was effective in preventing recurrence of the crust attachment to the tracheal membrane, thus, the tracheostoma was closed by the 17th postoperative day. This case indicates that among healthy people there are extremely rare patients with congenital tracheal stenosis who survive their postnatal and infantile periods, and who experience no trouble in their daily lives. As physicians, we must be aware of this disease in adult patients in our clinics.View full abstractDownload PDF (3455K) -
[in Japanese]1999 Volume 102 Issue 11 Pages 1262-1265
Published: November 20, 1999
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSDownload PDF (6562K) -
[in Japanese]1999 Volume 102 Issue 11 Pages 1266-1267
Published: November 20, 1999
Released on J-STAGE: October 22, 2010
JOURNAL FREE ACCESSDownload PDF (204K)
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