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Volume 105, Issue 7
Displaying 1-5 of 5 articles from this issue
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Enatsu Shibuya, Norihiko Asahina, Emiko Suzuki, Harumi Suzaki2002 Volume 105 Issue 7 Pages 783-789
Published: July 20, 2002
Released on J-STAGE: March 19, 2008
JOURNAL FREE ACCESSUsing 1952 dysosmia patients, we studied the difference in olfactory response to 5 types of odorous substances used in the standard olfactory acuity test in Japan-β-phenyl ethyl alcohol, methyl cyclopentenolone, isovaleric acid, γ-undecalactone, and scatol.
Olfactory dysfunctions included 887 patients with chronic paranasal sinusitis, 255 with allergic rhinitis, 326 with common cold sequela, 77 with omplications from head injuries, 28 with drug-induced dysosmia, 39 with congenital dysosmia, 257 with dysosmia of unknown etiology, and 83 miscellaneous.
The standard olfactory acuity test before treatment indicated that 82 patients detected only one odor within the detection threshold and 157 within the recognition threshold;40 responded only to isovaleric acid at the detection threshold and 101 at the recognition threshold. Both figures were ignificantly greater than those who responded to other odors(p<0.01). No specific trends were noted in etiologies of dysosmia that allowed smelling of isovaleric acid only either at the detection or recognition threshold.
Among those whose olfactory thresholds were judged to be scaled out against all 5 odorous substances, 552 were rated as scaled out at the detection threshold and 630 at the recognition threshold. During post treatment, 33 scaled out at the detection threshold and 32 scaled out at the recognition threshold improved enough to smell 1 type of odor. Of these, 15 scaled out at the detection threshold and 13 scaled out at the recognition threshold became able to smell only isovaleric acid. Those becoming able to smell only isovaleric acid either at the detection or recognition threshold, significantly outnumbered those becoming able to smell other odors(p<0.01). No outstanding cause of dysosmia was seen in those able to smell isovaleric acid.
This data indicates that olfactory function for detecting isovaleric acid is relatively resistant to disease and is most likely to be restared. The difference in olfactory response of patients with olfactory dysfunction such as those above may be due to variations in the number of olfactory receptor proteins for specific odors within olfactory cells or different responses to the type of molecules of odor-emitting substances.View full abstractDownload PDF (1190K) -
Hiroshi Miyahara, Katsunari Yane, Yoshihiro Tsuruta, Hirokazu Uemura2002 Volume 105 Issue 7 Pages 790-798
Published: July 20, 2002
Released on J-STAGE: December 15, 2008
JOURNAL FREE ACCESSWe retrospectively analyzed 213 patients-197 men and 14 women aged 40 to 87 years-with laryngeal cancer treated at our department from September 1986 to December 1997. The male to female ratio was about 12:1. Cases included 120 glottic (56.3%), 90 supraglottic (42.3%), and 3 subglottic (1.4%). Radiotherapy for early cases and surgery, mainly total laryngectomy for T3 and T4 were conducted first. The 5-year cause-specific survival by site was 97.6% glottic and 77.5% supraglottic. The five-year survival was 88.6% overall. Local control was 83.8% in glottic T1a and 84.6% in glottic Tib. The 3-year preservation of the larynx was 89.1% in glottic T1a and 92.3% in glottic T1b. Distant metastases were observed in 14 cases, mostly to the lung, bones, and liver. At high risk for distant metastasis were those with supraglottic T3-T4, N1, N2b, or pN2c.View full abstractDownload PDF (2146K) -
Masakazu Hanamitsu, Mikio Suzuki, Hiroya Kitano, Tsuyoshi Kitanishi2002 Volume 105 Issue 7 Pages 799-803
Published: July 20, 2002
Released on J-STAGE: March 19, 2008
JOURNAL FREE ACCESSDownload PDF (908K) -
Shinichi Yoshida, Hiromi Orihara, Touru Tanino, Takeshi Oshima2002 Volume 105 Issue 7 Pages 804-811
Published: July 20, 2002
Released on J-STAGE: March 19, 2008
JOURNAL FREE ACCESSDownload PDF (1322K) -
Hiroo Umeda, Akira Takagi, Shinichi Sato, Kazuhiro Yamakawa2002 Volume 105 Issue 7 Pages 812-815
Published: July 20, 2002
Released on J-STAGE: March 19, 2008
JOURNAL FREE ACCESSWe report a unique case of neurinoma originating from the tympanic plexus. A 23-year-old man reparting hearing impairment was found in otoscopic examination to have a tumor contour identified through the ear drum. Computed tomography showed that the tumor extended from the hypotympanum to the mesotympanum, eroding the promontory. A small specimen obtained after myringotomy indicated neurinoma. The man did not report facial weakness or taste disturbance. When we operated to remove the tumor, we found the long crus of Incus had disappeared and the stapes superstructure was dislocated upward due to the tumor expanse. Pathologically, the extirpated tumor was neurinoma of Antom A. A postoperative salivary gland function test using Tc showed hypofunction at the lesion side of the parotid gland. We surmise that neurinoma originated from the tympanic plexus because of its location and its lack of a relationship to the chorda tympanic nerve or facial nerve.View full abstractDownload PDF (1902K)
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