Nippon Jibiinkoka Gakkai Kaiho
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
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Volume 111, Issue 11
Displaying 1-5 of 5 articles from this issue
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Review article
Original article
  • Usefulness of Cephalometry and Pharyngeal Findings in the Primary Diagnosis of Obstructive Sleep Apnea Syndrome
    Takuro Kitamura, Akiko Sakabe, Narihisa Ueda, Teruo Shiomori, Tsuyoshi ...
    2008 Volume 111 Issue 11 Pages 695-700
    Published: 2008
    Released on J-STAGE: February 25, 2010
    DOIhttps://doi.org/10.3950/jibiinkoka.111.695
    JOURNAL FREE ACCESS
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    We studied the usefulness of cephalometry and pharyngeal findings in determining efficient primary diagnosis of obstructive sleep apnea syndrome (OSAS).
    Subjects were 171 adult men with sleep-disordered breathing, who underwent cephalometry and polysomnography (PSG) and had pharyngeal findings evaluated by modified Mallampati grade (MMP) and palatine tonsil size. An apnea-hypopnea index (AHI) of ≥15 in PSG was considered to indicate OSAS. We analyzed the correlation between AHI and other parameters and conducted stepwise multiple regression analysis to predict AHI, and studied the screening performance of prediction equations using a receiver operating characteristic (ROC) curve.
    Of the 8 cephalometric parameters examined, the length of the soft palate (PNS-P; p=0.011) and the distance from the mandibular plane to the hyoid bone (MP-H; p<0.001) correlated significantly with AHI. Two indices of the pharyngeal finding and body mass index (BMI) also significantly correlated with the AHI (MMP; p<0.001, tonsil size; p=0.005, BMI; p<0.001). We next set up three prediction equations including (a) two significant cephalometric parameters (PNS-P and MP-H), (b) two pharyngeal indices (MMP and tonsil size), or (c) both. BMI was included in all three. ROC curve analysis showed that the screening performance of prediction equations was (c)>(a)>(b). Sensitivity and of equation (c) with a cutoff of 15 were 0.95 and specificity 0.25.
    These results indicate that both cephalometric parameters and pharyngeal indices should be included in conducting an efficient primary diagnosis for OSAS.
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  • A Case of Laryngeal Sarcoidosis Difficult to Diagnose
    Jirou Iimura, Wataru Konno, Saori Koizumi, Satsuki Yasumura, Masatsugu ...
    2008 Volume 111 Issue 11 Pages 701-704
    Published: 2008
    Released on J-STAGE: February 25, 2010
    DOIhttps://doi.org/10.3950/jibiinkoka.111.701
    JOURNAL FREE ACCESS
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    Sarcoidosis is a multiorgan granulomatous disease of unknown cause, named after the characteristic histopathological findings of the disease. In this article, we shall report a case in which biopsy needed to be repeated three times until a final diagnosis of laryngeal sarcoidosis could be made.
    Since sarcoidosis associated with only a laryngeal pathology may not be associated with any laboratory abnormalities in many cases, first priority should be attached in suspected cases to detect the presence of noncaseating epithelioid cell granulomas. In this case, the results of the first and second laryngeal biopsies did not show non-caseating epithelioid cell granulomas, while the third biopsy showed noncaseating epithelioid cell granulomas with giant cells. Finally, the diagnosis of laryngeal sarcoidosis was made after the results of whole-body imaging became available.
    Laryngeal sarcoidosis must be borne in mind as a suspected diagnosis in cases where the larynx shows yellowish-white diffuse swelling.
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Educational lecture
Erratum
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