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Volume 111, Issue 7
Displaying 1-4 of 4 articles from this issue
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Original article
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Rieko Yamamoto, Seiji Hosokawa, Takashi Yamatodani, Sho Morita, Jun Ok ...2008 Volume 111 Issue 7 Pages 517-522
Published: 2008
Released on J-STAGE: September 01, 2009
JOURNAL FREE ACCESSSmall cell neuroendocrine carcinoma of the head and neck is rare, and diagnosis may be difficult. Malignancy is high, as is the incidence of distant metastasis. We reported eight cases of stage IV small cell neuroendocrine carcinoma of the head and neck, all in men with a mean onset age of 62 years (range: 45 to 80 years). Three cases arose from the maxillary sinus, two from the ethmoid sinus, one from the parotid gland, one from the tonsil, and one from the larynx. Histological analysis by hematoxylin-eosin staining tentatively revealed malignant lymphoma and undifferentiated carcinoma in two cases each, while immunohistological and/or electron microscopy analysis confirmed histological diagnosis. All were treated by chemotherapy (VP-16, CDDP) and seven cases with radiotherapy based on the schedule of small cell carcinoma of the lung and two cases with lesional resection. Chemotherapy and radiotherapy were effective locally. Five patients died of distant metastasis to the brain, bone, lung, liver, or skin within 12 months. One is alive with liver metastasis. Two have no evidence of disease, -one for eight years and the other for one year. Long-term survival thus requires the effective treatment of distant metastasis.View full abstractDownload PDF (1919K) -
Satoshi Yoshioka, Kensei Naito, Naoko Fujii, Kazuhiro Katada, Kenji Ta ...2008 Volume 111 Issue 7 Pages 523-532
Published: 2008
Released on J-STAGE: September 01, 2009
JOURNAL FREE ACCESSWe clarified the disease pathophysiology caused by Eustachian tube disfunction by examining the difference in each age of the Eustachian tube form. We measured the living human Eustachian tube using multislice CT (MSCT). Comparing without skew or contraction in case of cadaveric spesimens the length of each part of the Eustachian tube, the diameter, and the angle based on the image data obtained by MSCT for all age groups in our study, which involved 48 samples from adults and 31 from chidren (23 ears under 7 years old). We classified specimens from those less than 6 years old as the infant-youngchildren group, and from those 7 years or older as the schoolchildren-adult group.
Mean total length, cartilage part length, and bony part length was, as expected, longer in schoolchildren-adult group than infant-youngchildren group, as was the pharyngeal orifice diameter. The mean angle between the bony part and cartilage part was more acute in schoolchildren-adult group, as was the cartilage part steepness. We proved a characteristic of three-dimensional anatomy of a child Eustachian tube in living human organism.View full abstractDownload PDF (962K) -
Akira Okoshi, Kiyoto Shiga, Kazuha Sasaki, Yukinori Asada, Hitoshi Nis ...2008 Volume 111 Issue 7 Pages 533-536
Published: 2008
Released on J-STAGE: September 01, 2009
JOURNAL FREE ACCESSWe report two cases of radiation-induced sarcoma after chemoradiation therapy in nasopharyngeal carcinoma.
Case 1: A 40-year-old man developed a malignant peripheral nerve sheath tumor (MPNST) in the posterior floor of the nasal cavity 10 years after treatment for nasopharyngeal cancer. Case 2: A 64 year-old man developed a malignant fibrous histiocytoma (MFH) of the lower gum 10 years after treatment of nasopharyngeal cancer. Despite radical surgery, the man with MPNST had a recurrent tumor and died of the disease.View full abstractDownload PDF (1290K)
Educational lecture
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[in Japanese]2008 Volume 111 Issue 7 Pages 542-545
Published: 2008
Released on J-STAGE: September 01, 2009
JOURNAL FREE ACCESSDownload PDF (195K)
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