Nippon Jibiinkoka Gakkai Kaiho
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
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Volume 117, Issue 7
Displaying 1-18 of 18 articles from this issue
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Review article
Original article
  • The Accuracy of Evaluating the Response of Metastatic Lymph Nodes after Concurrent Chemoradiotherapy in Patients with Head and Neck Squamous Cell Carcinoma
    Goshi Nishimura, Masanori Komatsu, Takahide Taguchi, Masahiro Takahash ...
    2014 Volume 117 Issue 7 Pages 899-906
    Published: July 20, 2014
    Released on J-STAGE: August 08, 2014
    DOIhttps://doi.org/10.3950/jibiinkoka.117.899
    JOURNAL FREE ACCESS
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    Background: Concurrent chemoradiotherapy (CCRT) is used to treat advanced head and neck cancer. The accuracy of evaluating lymph nodes metastases following CCRT is important for subsequent therapy. Patients and Methods: Patients were divided into two groups according to the nodal status, the complete response (CR) and the non-CR groups, as determined by imaging and fine-needle aspiration cytology (FNAC) performed 4-8 weeks after the CCRT, and the findings were compared with the status 6 months after the treatment completion. Results: The sensitivity, the specificity, positive predictive value, negative predictive value and accuracy of each evaluation method were as follows: 66.7%, 73.5%, 26.7%, 93.8% and 72.5%, respectively, for computer tomography (CT) and magnetic resonance imaging (MRI); 91.7%, 69.9%, 30.6%, 98.3% and 72.6% for ultrasonography (US); 50.0%, 96.4%, 66.7%, 93.0% and 90.5% for fluorodeoxyglucose-positron emission tomography (FDG-PET) or PET-CT; and 68.4%, 96.1%, 81.3%, 92.5% and 90.6% for FNAC. Conclusion: To evaluate the response of lymph node(s) treated by CCRT, US is useful as a positive screening tool and FDG-PET and PET-CT as negative screening tools. FNAC is useful in evaluating suspicious lymph nodes in both positive and negative cases.
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  • Outcome of Tongue Cancer Treated with Surgery and Postoperative Radiotherapy
    Motoyuki Suzuki, Kunitoshi Yoshino, Takashi Fujii, Masashi Yoshii, Tos ...
    2014 Volume 117 Issue 7 Pages 907-913
    Published: July 20, 2014
    Released on J-STAGE: August 08, 2014
    DOIhttps://doi.org/10.3950/jibiinkoka.117.907
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    A retrospective analysis of 263 patients with previously untreated squamous cell carcinoma of the tongue between 2000 and 2010 was performed. Those patients, who received preoperative chemotherapy, had a history of head and neck cancer or had previously received radiotherapy for the other disease, were excluded. All patients underwent a surgical procedure as a part of the initial treatment. Patients with close or microscopically involved margins of resection, INF (Infiltrative growth pattern) γ or at least two involved nodes were classified as high risk patients. Postoperative radiotherapy (PORT) was undertaken for the high risk patients. After a median follow-up of 72 months, the 5-year overall survival and 5-year cause-specific survival were as follows: 79.1%, 85.0% in all stages, 82.7%, 91.2% in Stage I (n=76), 86.7%, 89.0% in Stage II (n=98), 71.5%, 78.6% in Stage III (n=57), and 61.5%, 69.1% in Stage IV (n=32). Patients without high risk features had significantly higher overall survival rate than those in the case of high risk patients, despite receiving no PORT. For high risk patients, PORT significantly improved the locoreginal control rate, but the overall survival rate did not improve.
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  • Usefulness of Thyroid and Neck Lymph Node Screening with Carotid Artery Ultrasonography
    Nobuyuki Bandoh, Takashi Goto, Yasuaki Harabuchi
    2014 Volume 117 Issue 7 Pages 914-921
    Published: July 20, 2014
    Released on J-STAGE: August 08, 2014
    DOIhttps://doi.org/10.3950/jibiinkoka.117.914
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    Ultrasonography of the carotid artery is routinely used to diagnose carotid artery stenosis and to screen the severity of atherosclerosis. During the performance of the ultrasonography, thyroid lesions or neck lymph node swelling are often observed. In this study, a total of 30,351 persons underwent carotid artery ultrasonography for thyroid and neck lesions as well as the carotid artery from 2008 to 2012. Criteria for further examination were either nodules with high echoic lesions indicating calcification, nodules 2cm or greater in diameter, malignant findings such as irregular shape, ill-defined border character, low and heterogeneous internal echoes, or diffuse swelling in the thyroid. Furthermore, neck lymph node swelling was also included in the criteria. Further examination was required in 650 (2.2%) of all 30,351 persons. In our hospital, 394 (60.6%) patients of the 650 were able to be examined with detailed ultrasonography and/or fine needle aspiration biopsy for thyroid and neck lesions. Finally, 73 patients (0.24%) were diagnosed as having malignant tumors consisting of 67 thyroid papillary carcinoma, two malignant lymphoma, one laryngeal carcinoma, one oropharyngeal carcinoma, one hypophryngeal carcinoma and one parathyroid carcinoma. Findings of the carotid artery ultrasonography for further examination were nodules with high echoic lesion in 370 (56.8%), nodules of 2cm or greater in diameter in 197 (30.2%), malignant findings in 120 (18.4%), diffuse swelling in 38 (5.8%) in the thyroid, and neck lymph node swelling in 38 (5.8%) of the 650 patients. The frequency of the malignant findings and neck lymph node swelling in the carotid artery ultrasonographic findings in thyroid carcinoma patients was significantly higher compared to those in patients with benign thyroid lesion. The tumors in 56 thyroid carcinoma patients which were detected with the carotid artery ultrasonography showed a significantly smaller and earlier stage in pT and pN compared to those in 21 thyroid carcinoma patients who consulted with subjective symptoms. These findings suggested that screening for thyroid and neck lesions in the performance of carotid artery ultrasonography is useful and needs to be widely adopted to reveal head and neck malignant tumors and early stage thyroid carcinomas.
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  • Surgical Approach of Lateral Temporal Bone Resection for Treatment of Head and Neck Cancer with Invasion Surrounding the Jugular Foramen
    Akiteru Maeda, Yoshihisa Ueda, Takeharu Ono, Buichiro Shin, Shun-ichi ...
    2014 Volume 117 Issue 7 Pages 922-927
    Published: July 20, 2014
    Released on J-STAGE: August 08, 2014
    DOIhttps://doi.org/10.3950/jibiinkoka.117.922
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    We herein present a review of the surgical approach of lateral temporal bone resection (LTBR) in the treatment of 5 cases of head and neck cancers invading the jugular foramen between 2008 to 2013.
    The patients comprised 3 males and 2 females with ages ranging from 25 to 76 and observation times were between 13 and 22 months. In this study we reviewed the method of operation and treatment. Four patients are alive, but one patient died from the primary disease. Complications occurred including postoperative facial nerve palsy and hearing loss. Although the LTBR with jugular foramen approach can cause postoperative facial nerve palsy and hearing loss, this method would be recommended as a safe surgical procedure for its wide surgical field. We therefore propose that this LTBR technique is useful for patients with head and neck cancer extending to the jugular foramen.
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  • A Case of Swelling of Salivary Gland due to Drug Treatment for Threatened Premature Labor
    Hiroshi Kimura, Hiroyoshi Yuki
    2014 Volume 117 Issue 7 Pages 928-931
    Published: July 20, 2014
    Released on J-STAGE: August 08, 2014
    DOIhttps://doi.org/10.3950/jibiinkoka.117.928
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    Ritodrine hydrochloride (luteonin®), a β-agonist with predominant effects on βadrenoreceptors such as those of the uterus, is effective in suppressing premature uterine contractions. This medicine was used in drug treatment in the case of threatened premature labor. A 26-year-old female who complained of acute swelling of the bilateral salivary glands was consulted to our otorhinolaryngological department. The soft swelling of the bilateral parotid and submandibular glands had developed after intravenous administration of ritodrine hydrochloride for treatment of her threatened premature labor. In addition, serum amylase levels were elevated. The swelling of the salivary glands and the elevation of the serum amylase subsided following discontinuation of the ritodrine hydrochloride. In salivary glands, too, the β-adrenoreceptors exist. Following stimulation of those receptors in those glands increased secretion of amylase occurs. Our findings suggested that β-stimulation by ritodrine hydrochloride led to the swelling of the salivary glands and the elevation of the serum amylase. To our knowledge, in Japan, our case is the first otorhinolaryngological report of swelling of the salivary glands due to ritodrine hydrochloride. Otolaryngologist should therefore have full knowledge regarding swelling of salivary glands due to ritodrine hydrochloride.
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  • A Case Report of Parkinson's Disease Presenting with Olfactory Disturbance as a Primary Symptom in the Early Stage
    Hisami Fujio, Go Inokuchi, Yuriko Fukuda, Shingo Hasegawa, Naoki Ootsu ...
    2014 Volume 117 Issue 7 Pages 932-935
    Published: July 20, 2014
    Released on J-STAGE: August 08, 2014
    DOIhttps://doi.org/10.3950/jibiinkoka.117.932
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    We report herein on a 71 year-old male who presented with olfactory disturbance at the early stage of Parkinson's disease (PD). Due to a persistent olfactory disturbance for 5 years, the patient visited our clinic and showed disorientation between the olfactory detection threshold and recognition in T&T olfactometry and scored 3 out of 12 points in OE. During the follow-up period, the typical symptoms of PD, including mask-like face and motor disturbance emerged, which led to the diagnosis of PD by the neurologist. Since it is generally accepted that olfactory disturbance precedes the appearance of motor disturbance in the early stage of PD, otolaryngologists should be aware of the necessity of olfactory tests for the patients with reported persistent olfactory disturbance, especially in elderly patients. In those cases where the patients present positive findings in olfactory tests without any particular cause, referral to neurologists is recommended.
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