To disclose the association of house dust antigen with chronic tonsillitis, studies were made on the procedure of preparing house dust extract and on its properties as an antigen. The association was confirmed by clinical, investigation of intradermal reaction conducted in cases of chronic tonsillitis along with diseases of the nose and sinuses.
Extract prepared from home dust in Japanese houses contains undoubtedly an antigenic substance and intradermal reaction following to injection of the extract results from antigen-antibody reaction. Since the skin reaction may be caused also by non-specific irritant contained in the extract, the reaction due to the antigenic substance is hardly differentiated by making use of Solution No. 1 and No. 2 (containing 0.1mg and 0.02mg of nitrogen, respectively). Tne sensitization with house dust should be determined by making use of Solution No. 3 which contains only 0.01mg of nitrogen.
Nitrogen content in the house dust extract may be regarded as an index of antigen titer.
The extract is preserved well with little decrease in potency for a considerable period of time at room temperature, so long as it was sealed in ampule, following to the extraction from Coca's alkaline solution and neutralization with phenolphthalein as an indicator.
In cases of chronic tonsillitis complicated with focal infection, the rate of positive reactors to the extract averaged 59.0 per cent, while those without complications gave a positive rate of 42.5 per cent. The difference was proved evident. As to the complications of focal infection, the skin reaction was positive in 63.6 per cent of chronic cases of tonsillitis with rheumatism and in 58.8per cent of those with nephritis. The same result was obtained by employing extract of higher dilution.
As to diseases of the nose and sinuses, the rates of positive intradermal reaction in allergic rhinitis, chronic sinusitis and chronic rhinitis were 55.0 per cent, 37.3 per cent, respectively.
Positive rate of skin reaction before and after tonsillectomy differed little from each other.
Mechanism of focal infection has never beestudied from the standpoint of antigenic substance introduced from the outside. Although home dust antigen which was inhaled through the respiratory passages was found not to be primary causes of focal infection, the present paper suggests some relation at least to manifestation of focal infection, and elucidation of the particular relationship depends much upon further studies.

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The influence of tonsillar massage and ultra-short-wave irradiation upon the body temperature was observed in 320 patients with chronic tonsillitis. Following to the tonsillar massage for 5 minutes, the temperture war examined 5 minutes, 15 minutes, 45 minutes, 1 hour and 3 hours offer the stimulation. Also, after ultra-short-wave irradiation to both tonsillar regions for 5 or for 5 minutes, the examination of thetemperature was made 5 minutes, 15 minutes, 45 minutes, 1 hour and 3 hours after the irradiation.
The control group was also studied.
Provocative responses of the temperature was most remarkable in the patients with tonsillar systemic diseases, such as slight fever, rheumatoid arthritis and nephritis.
In patients with tonsilar complications, the temperature increase was maximum at 15 minutes after tonsillar massage and the patients without such complications showed the highest rise 45 minutes after that stimulation while after the irradiation by ultra-short-wave the temperature increase was most remarkable at 15 minutes in those either with or without secondary complications.
Ultra-short-wave irradiation was preferable to tosillar massage and the irradiatioh for 15 minutes was most advisable.
The stimulations upon the patients with systemic diseases showed their greatest effects in 45 minutes and the effects after one to 3 hours were of no significance.
In control group, rise of the temperature after both provocations never exceeded more than 0.5°C.
From the results above mentioned, in patients with chronic tonsillitis the temporary rise of body temperature more than 0.5°C 15 minutes after the stimulation may be admitted to be diagnostically significant.

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The influence of tonsillar massage and ultra-short-wave irradiation upon the leukocyte count was observed for 3 hours after provocations.
Results obtained were as follows:
Changes at 3 hours after the provocation by the massage were most remarkable also, changes 45 minutes after five-minute-irradiation and 3 hours after 15 minute irradiation were remarkable.
Ultra-short-wave stimulation was preferable than tousillar massage and irradiation for 15 minutes was most desirable.
The stimulation upon the patients with tonsillar systemic diseases showed great effects but the examination 5 minutes and at 15 minutes after the provocation was of little significance.
As for tonsillar systemic diseases, the temporary increase in lenkocyte count through provocation was recognized especially in patients with slight fever, rheumatoid arthritis and nephritis, being not so remarkable with the other systemic diseases.
In the control group, temporary increase of leukocyte count due to provocation was not more than 1000 cells per cu. mm, whereas in the case of chronic tonsillitis without any tonsillar diseases, the increase of leukocyte count was higher than 1000 cells per cu. mm., but not more than 2000 per cu. mm. In those with some tonsillar complications, the increase of lenkocyte count was 2000 to 3000 in 9 to 14% by the massage and in 14 to 17% by the ultra-short-wave irradiation.
From the results above mentioned, in patients with chronic tonsillitis (either those who have some systemic disease or not), the temporary increase of leukocyte count more than 1000 cu. mm., examined 15 minutes after ultra-short-wave stimulation may be one of the most favorable diagnostic standards.
The changes of the differential leukoyte count by the provocation were as follows:
Before the stimulation, in patients of chronic tonsillitis with some or without any tonsillar diseases, increase of lymphocytes, neutrophils and eosinophils were observed and but there was no increase of monocytes and basophils. Increase of plasma cells was found in those who had sytemic complicatioes.
After the stimuiation, in patients of chronic tonsillitis with some or without any tonsillar diseases, increase of lymphocytes, neutrophils and eosinophils were most remarkable 3 hours after the stimulation in those who had systemic cemplications. The plasma cells were also increased.
In the patients of the rheumatoid arthritis increase of lymphocytes and neutrophils were observed after the stimulation and in those who had rheumatoid arthritis, slight fever and heart disease, the plasma cells were increased.
From the results above mentioned, the apdearance of plasma cells and the increase of neutrophils 3 hours after the provocation were proved to be diagnostically significant.

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The temporary accelaration of blood sedimentation rate due to tonsillar provocation was observed.
The results obtained were as follows:
The best provocative response was obtained 3 hours after the stimulation and the effects in patients with tonsillar systemic diseases were more distinct than that in those without any secondory diseases. The use of ultra-short-wave were preferable than massage and the irradiation for 15 minutes was most adivisable.
Regarding tonsillar systemic diseases, by both method of stimulation, the remarkable responses were seen in patients of tonsillar rheumatoid arthritis and nephritis, but not in other systemic diseases.
In control group, the temporary accelaration of the blood sedimentation rate due to provocation was always less than 10mm. in one hour.
From the results above mentioned, the acceleration more than 10mm. of the blood sedimentation rate was proved to be the diagnostic standards.
As for the difference between before and at 3 hours after the provocations, changes of about 1mm. in one hour after tonsillar massage, 0.7mm after the ultra-short-wave irradiation for 5 minutes, 1.2mm for 15 minutes inadiation in the patients of chronic tonsillitis without any systemic diseases, 1.6mm after tonsillar massage, 2.2mm after ultra-short-wave irradiation for 5 minutes, 2.5mm for 15minutes irradiation in those who had tonsillar complication were admitted to be significant respectively.

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Applying provocative stimulation to the patient of chronic tonsillitis with or without tonsillar systemic complications, changes in urine were examined.
In patients of chronic tonsillitis especially with tonsillar systemic dideases, the increase of albumin and erythrocytes was recognized, and it was most remarkable 3 hours after provocation.
Both the provocative stimulation made no remarkable changes with regard to glucose, leukocytes, desquamative cells and cast in urine while the appearance of cast in urine after tonsillar massage on the patients with tonsillar systemic diseases were considered to be diagnostically significant.
Concerning provocation, either ultra-short-wave irradiation or tonsillar massage will do for the provocative use.
In patients of chronic tonsillitis without any systemic complications, no distinguishing provocative responses in urine were observed.
From the results above mentioned, after the provocative stimulations, the increase and appearance of albumin and erythrocytes in urine of the patients who have systemic diseases were admitted to be diagonstically useful, while changes in urine of those without any tonsillar diseases were of little significance.

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Provocative responses of 30 tonsillectomized patients, who had been determined as positive in the series of our tests, were reprovocated within one to six months after the operation.
Resnlts obtained and evaluated were as follows:
In 7 patients of chronic tonsillitis without any systemic diseases who had been determined as positive in the series of our tests reprovocative responses turned to negative within 3 months after the operation.
In 23 patients of chronic tonsillitis with some systemic diseases who had been diagnosed as positive in our provocative tests, all of them revealed negative responses within 6 months after the operation.
As for tonsillar systemic complications, all 23 patients who had been suspected to be accomponied with tonsillar systemic diseases recovered from their illness when the tests turning into negative after the operation. At any rate, our tests before the operation was proved to be a very useful guide for tonsillectomy.

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Inflammatory changes in the fine blood vessels in various parts of the nose of rabbits were studied. As a preliminary experiment, cast models of the capillary plexus in the nose of the normal rabbit were made by injecting latex, which served as the control. The capillary plexus in anterior portion of the septum and lateral wall, maxillo-turbinal, and free edge of ethmo-turbinal was dense and that in the posterior portion of the septum and lateral wall, and maxillary sinus was sparse. The capillaries, forming more or less regular network, were not intermitted or destructed. The net blood capillaries were about 20μ in diameter, and those in maxillary sinus, 8μ in diameter, were extremely thin.
The experimental rhino-sinusitis was induced in rabbits by injecting staphylococci into maxillary sinus. The cast models were made as described. Capillaries in acute inflammation and acutely exacerbated stage of chronic inflammation were markedly intermitted, and destructed and the latex wereleaked out from blood vessels. Dilatation of the vessels continued for a little while after the cessation of acute symptoms. In both acute and chronic inflammation, regeneration of the vessels occured in the middle of septum, the ethmo-turbinal and the maxillo-turbinal. In chronic inflammation, the capillary walls were irregular and the vessels ran windingly, but were not intermitted, destructed, and leaked so markedly as seen in acute stage. Generally speaking, pathologic changes were severe in the dense parts of capillary plexus, but subdued rapidly, and mild in the sparse parts, but prolon ged. It took more than a week for inflammatory changes to abate. After several repeated attacks of acute inflammation for about four months, the lesion became irreversible.
Findings of the cast model in every condition of rhino-sinusitis were well in accord with the histopathologic changes.

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Fifty-two patients with atrophic rhinitis were divided into 3 groups, Iab, Ic and II, according to Kitamura's classification. The functional activities of some of the epidermal organs and mesenchymal tissue, as well as of the autonomic norve, were investigated, and the factors affecting the course of atrophic degeneration of nasal construction were examined from constitutional point of view. Patients with chronic sinusitis, who served as controls, were also examined.
As for the function of epidermal organs, the amount of secretion from the salivary glands and sweat glands was less in atrophic rhinitis than in chronic sinusitis. There was no difference in excitability of the vagus nerve between the two diseases. Atrophic rhinitis showed a higher incidence of abnormal sialographic findings in the parotid gland than chronic sinusitis. This observation may indicate some organic changes in the glands. As for the function of mesenchymal tissue, instability of the vasomotor nerve and fragility of the capillaries, as well as delayed reaction of the skin to Cantharidin, were specific in atrophic rhinitis. Review of consititutionl history revealed that patients with atrophic rhinitis were more predisposed to mucosal infections, with a higher incidence of other otorhinolaryngeal diseases. It seemed that they were slow in reacting to inflammatin and that inflammatory changes tend to become chronic.
Nasal sinuses were more poorly developed in patients with type Iab atrophic rhinitis than that in those with chronic sinusitis, indicating that congenital local factors might be concerned in the course of atrophic rhinitis of this type. Nasal mucosa of type II had atrophied after long severe rhinosinusitis, in spite of congenital local hyperplastic constitution of nasal mucosa, which had appeared in good developed paranasal sinuses. This seems to indicate that general factors are concerned in the development of atrophic rhinitis of this type. It was considered most likely that, in the development of type Ic atrophic rhinitis local unknown factors other than those that were found in the other two types were concerned, and that the same general factors as were found in the other two types were concerned in its development.

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In order to find the relation of the diseases of nose and pharynx to V.A metabolism, the quantities of V. A in the blood of 108 patients (including 34 children) were measured and comparing them with those of 22 healthy adults and those of 17 healthy children the following result was obtained:
The average value of V.A in the blood of the patients of atrpphio rhinitis was 122.5±10.71I.U. and that of thoase of chronic sinuitis maxillaris 138.7±5.84I.U. These values were lower than 158.2±4.60I.U. of the healthy adults and the tendency was more significant in the group of the patients of atrophic rhinitis.
By the fact that, after the operation of chronic sinuitis maxillaris, the rise of V. A quantity was not always apparent and through the observation of referential literatures it was presumable that at least some of the disease had a certain relation original in its cause.
The average V.A value of the patients of palatine tonsillar lrypertrophy was found to be 112.4±6.69I.U. and that of those of adenoi d 116.3±12.96I.U. and it was noted that these values were not much different from 128.1±7.12I.U. of thehe althy children. The average V.A value of the group of the patients of simple chronic tonsillitis was 182.3±7.07I.U. (161.4±10.84I.U. for children), which were sensibly high compared with thos eof the healthy adults and children, respectively. In the group of the patients of tonsillar focal infection it wasp resumable that these patients were in a conditioe likely liable to the affection of a secondary disease. The patients of low fever (119.0±4.52I.U.) and articular rheumatism (122.2±9.32I.U.) had an average value sensibly lower and those of heart troubles (152.9±7.14I.U.) had an average value apparently lower than that of the healthy adults. In the patients of chronic nephritis (222.2±12.69I.U.) only howevera high a verage value of V.A was recognized as an exception.
Looking at the group distribution of various patients whose average V.A value was lower than the normal, comparing with 23.6% in the healthy children, 46.6% among the patients of chronic tonsillitis and 40% among the patient with adenoid vegetation. On the other hand, in the case of the adult patients of chronic tonsillitis it was not found so in the group of the patients of simple chronic tonsillitis, but there were 29% in the group of the patients of tonsillar focal infection only. High values above 150I.U., however, compared with 67.7% in contrast, it was as high as 80% in the group of the patients of chronic tonsillitis, and in the group of those of focal infections, with an exception of 85.7% for those of chronic nephritis, 50% for heart troubles, 12.5% for articular rheumatism and 0% for low fever, respectively.
In the cases of palatine tonsillar hypertrogslry and adenoid vegetation of children, no clear correlation was found between the value of V.A quantity in the blood and the degree of nuturition appraised by means of the measurement of the upper arm circumference.

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In order to find the relation of the diseases of nose and pharynx to V.A metabolism, the quantities of V. A in the blood of 108 patients (including 34 children) were measured and comparing them with those of 22 healthy adults and those of 17 healthy children the following result was obtained:
The average value of V.A in the blood of the patients of atrpphio rhinitis was 122.5±10.71I.U. and that of thoase of chronic sinuitis maxillaris 138.7±5.84I.U. These values were lower than 158.2±4.60I.U. of the healthy adults and the tendency was more significant in the group of the patients of atrophic rhinitis.
By the fact that, after the operation of chronic sinuitis maxillaris, the rise of V. A quantity was not always apparent and through the observation of referential literatures it was presumable that at least some of the disease had a certain relation original in its cause.
The average V.A value of the patients of palatine tonsillar lrypertrophy was found to be 112.4±6.69I.U. and that of those of adenoi d 116.3±12.96I.U. and it was noted that these values were not much different from 128.1±7.12I.U. of thehe althy children. The average V.A value of the group of the patients of simple chronic tonsillitis was 182.3±7.07I.U. (161.4±10.84I.U. for children), which were sensibly high compared with thos eof the healthy adults and children, respectively. In the group of the patients of tonsillar focal infection it wasp resumable that these patients were in a conditioe likely liable to the affection of a secondary disease. The patients of low fever (119.0±4.52I.U.) and articular rheumatism (122.2±9.32I.U.) had an average value sensibly lower and those of heart troubles (152.9±7.14I.U.) had an average value apparently lower than that of the healthy adults. In the patients of chronic nephritis (222.2±12.69I.U.) only howevera high a verage value of V.A was recognized as an exception.
Looking at the group distribution of various patients whose average V.A value was lower than the normal, comparing with 23.6% in the healthy children, 46.6% among the patients of chronic tonsillitis and 40% among the patient with adenoid vegetation. On the other hand, in the case of the adult patients of chronic tonsillitis it was not found so in the group of the patients of simple chronic tonsillitis, but there were 29% in the group of the patients of tonsillar focal infection only. High values above 150I.U., however, compared with 67.7% in contrast, it was as high as 80% in the group of the patients of chronic tonsillitis, and in the group of those of focal infections, with an exception of 85.7% for those of chronic nephritis, 50% for heart troubles, 12.5% for articular rheumatism and 0% for low fever, respectively.
In the cases of palatine tonsillar hypertrogslry and adenoid vegetation of children, no clear correlation was found between the value of V.A quantity in the blood and the degree of nuturition appraised by means of the measurement of the upper arm circumference.

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During one year from August, 1957 until August, 1958, the authors obtained 129 strains of Staphylococcus aureus (Coagulase Positive, Hemolytic) from earfuruncle patients in three districtsin Kyushu (Ureshino Town in Saga Prefecture, Moji City in Fukuoka Prefecture & Ooita. City in Ooita Prefecture) and we investigated the sensitivity of each strain to Penicillin, Streptomycin, Chloramphenocol, Tetracyclin, Erythromycin, then examined the regional differences in sensitivity.
In sensitivity to PC, the authors could not recognizo any significant differences among three districts. Sensitivity to SM declined in the order of Ureshino, Ooita, and Moji, Many of the Ooita strains were significantly low in sensitivity to TC compared with those from the other two districts, Moji, and Ureshino. In CM & EM, the authors did not recognize any differences at all among three districts.
Here in Kyushu area, Staphylococcus aureus has been gaining resistance against in the order of PC→SM→TC and the authors have not seen the strains resistance against CM & EM yet.

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The author conducted experiments with objective audiometry using psychogalvanic skin response, applying endsomatic method with balanced negative feed-back amplifier system. This apparatus could eliminate the disadvantages of exosomatic method which has been in use. Using this apparatus author tested 85 cases (7 months-62 years of age) with from normal hearing to severe hearing loss.
The results obtained were as follows:
1) Thirty-six cases, 68 ears (5.1-62 years of age) were tested by both P. G. S. R. audiometry and standard pure tone audiometry. Reliability in these two methods were within ±5db in 53.2%, and were within ±10db in 79.8%.
2) Average difference were 6.6db lower by P. G. S. R. audiometry than standard pure tone audiometry.
3) Eighty-five cases were classfied to three groups:
A) Cases responded to sound and shock and onditioned readily, 45 case, 52.9%.
B) Cases respoded to sound and shock and difficult or impossible or conditioning was not attempted, or threshold was not measured, 25 cases, 17.6%,
C) No response to sound or shock graphically, 15 cases, 17.6%.
4) Difficulty were increased under three years of age. The youngest subject successfully examined by P. G. S. R. audiometry was 2 years and 11 months old.
5) P. G. S. R. audiometry was successful in 80.6% over 10 years, and were successful in 37.0% under 10 years of age. Rate of successful test was higher in the group with hearing loss, especially in children under 10 years, satisfactory results were obtained in 41.8%.
6) Rate of successful test was not so high in P. G. S. R. audiometry alone. It is desirable to use several tests, such as play audiometry, speech audiometry and etc, so that more statisfactory results are obtained in clinical application.

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In order determine whether telephone deafness was caused by scoustio trauma or not, an efficiency of the telephones, auditory fatigue of the telephone operators and some conditions under which they were apt to suffer from telephone deafness were studied.
The results obtained were as follow:
1. The frequency ranges of the telephones were from 200 to 4000cps and the level of its sensitivity was 65db at 1000cps and its sensitivity: deviation between at 300cps and at 2500cps was only 10db. Therefore the sound pressure conducted to the ear of the operators was not over 70db.
2. Of 914 telephone operators, 17.7% had hearing impairment.
3. In the operators with normal hearing the level of auditory fatigue against one day work was within 15db and immunity from auditory fatigue was obtained with the increase of the years for which they worked. In operators who worked over 4 years the auditory fatigue was located in 500 to 2000cps. And in them who had worked over 8 years it was not recognized. On the other hand, in operators with telephone deafness it was from 15 to 30db.
4. As the reuslts of the function tests, of the automatic nervons system, vagotonia was observed frequently in the apprentices and operators with normal hearing, followed by the operators with deafness. Especially the difference of its frequency between in the operators with normal and impaired hearing was remarkable. Sympatheticotonia, changeable vagotonia and non-reaction were obserevd frequently in them with deafness.
5. As compaired with the operators with normal hearing, in the cases with deafness the irregular cellularityand absorption of the mastoid cells were more remarkable.
6. By using Sawada's urinalysis method, the values of vitamin-B1 in blood were measured. Thirty percent of the cases with normal hearing and 62% of them with deafness were foued to be deficient in vitamin-B1.
7. It is resonable to presume that telephone deafness is not caused by directors. As based on thase findings, it must be distinguished from usual occupational deafness.

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In 1008 cases of patients with nasal disease, their subjctive symptoms were observed statitically. Patients complained of disturbance of olfactory sense were 61 cases (6.0%), more frequent in chronic sinuitis and deviations of the septum, and had no sexual difference.
Child and old ages scarcely complained chiefly of disturbance of olfactory sense.

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1) The olfactory sense measured by dilution test decreasen in the older than 60 ages normal in health and in order of sinuitis, rhinitis atrophicans, deviatio septi nasi and rhinitis hypertrophicans. We found no significant; difference between male and female in the sense of smell normal in health.
2) Patients with nasal disease except severer hyposmie had the same taste as normal in health.

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1) Initial and terminal time of sense of smell surveyed by venous injection of Alinamine (Vitamine B1 preparate) were the following;
(a) Normal in health : 9.3sec, 170sec Hyposmia: 11.1sec, 60.5sec so-called Anosmia: 13.9sec, 48sec(the former: initial time, The latter: terminal time)
(b) The longer terminal time was the more sensitive olfactory mucous membrane.
2) In 15 cases with chronic sinuitis, we performed the venous olfactory test at a week and a month before and after its operation.
The results were followed; sense of smell had the tendency to improve a month postoperatively and only in patients whose mucous membranes of paranasal cavities were fibrous, and naaal findiugs improved corresponding with the result of its test.
At last, we stated that in 10cases of datients with deviations of the septum sense of smell improved only in r, ght indication of the operation.

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1) As the results of several examinations, we made the olfactorymeter almost satisfied various conditions, which made the basis inventing the smell tests.
2) The smell tests were divided in three; pressure, dilution and venous olfactoiy test. Principle, apparatus and method of each of these tests were stated.
3) From the results os these examinations, we could know of ihe olfactory disturbance dependent upon in nasal forms by pressure test and upon sensibility of olfactory mucous membrane by dilution test. venous olfactory test could survey for patients compelelty lost of nasal olfactory sense.

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The results of the olfactory test in mense, pregnancy anp climacterium were follower: subjective hyposmia and hyperosmia in each sexual phenomena weren't caused by change of the olfactory mechanism from the fact that there was not very masked difference in measures of the test, but were based on the peculiarity of a state of mind in each sexual phenomena; that is disturbance of the olfactory sense may be complained in tne individials presented a state of mind when we pay in such stages specitic allention to sense of smell in which we have not usually aninterest.

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The mucous memhrane of palate in adulte human is almost covered with cornificated stratified squamous epithelium and partially the ablation of stratum corneum is found. Thickness of the epithelium at hard palate is different due to its situation and runs mostly parallel with degree of the papillae-formation in lamina propria. At the intraepithelium of the frontolateral portion that has. large papillae at hard palate in human, the tastebuds which have not yet been reported judging from the literature available on this subject were discovered; and the fact is very interesting from the view•point of the organ of taste.
The nerve elements distributing in the mucous membrane of human palate are composed of thick myelinated sensory nerve fibres and fine unmyelinated ones. Sympathetic and parasympathetic fibres. are histologically indistinguishable, because they anastomose each other in places and have no differance in its structur. In general the nerve plexuses in the mucous membrane of palate are relatively well developed and chiefly consist of two large plexuses. The nerve plexus formed within tunica submucosa is loose netted, whereas the plexus in lamina propria is fine netted. The vessels and the nerve bundles emanating from these plexuses run mostly within loose connective tissue.
The terminal endings of sensory nerve fibres and the vegetative terminal reticulum distributing within papillae and adjacent to basal membrane are sent forth from the plexus of lamina propria, these developments are almost parallel with grade of the papillae-formation. These terminations have been investigated systematically in detail at the various regions of the mucous membrane of palate.
As the result the author classified respectively several forms about the ending-formations of intraepithelial nerve and the sensory nerve fibres and moreover succeeded in staining of the fine terminal reticulum of the vegetative fibres.
The relation between sensory and vegetative nerve fibres has been histologically investigated. The author found that the sensory nerve fibres farmed various complicated terminatians accompanying with the fine vegetative ones, and published in detail on the distribution.of the vegetative nerve fibres within the mucous membrane of palate of which the reports have been systematically very few.
Namely, appearance of the vegatative terminal reticulum towards the walls of blood vessels and capillary tubes as well as that within glandular. fatty and connective tissues etc. has been made clear.
The vegetative nerve anastomosis between perivascular plexuses and vegetative nerve fibres and the double networks between vegetative terminal reticulum and the net of capillary tubes are considered. to be the interesting fact clinically.

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The patient was a 58 years old male who had complained of left facial paralysis and hoarseness. An autopsy revealed craniopharyngioma which main tumor mass was located at left ventral portin. of the pons.
This tumor has grown up from diaphragm of Sella turcica, not from pituitary gland and pressed and invaded into sinistro-ventral portion of the pons from the left side, invading along dura mata into the surrounding tissues and the both side of tentrium cerebelli and has formed main tumor in it.
This of growth is rare and interesting as craniopharyngioma.
Histologically, the tumor is atypical craniopharyngioma showing the loss of ameloblast layer or incomplete adamantinomous type in most areas and simple squamous epithelioma in some areas.
The relationship between various nervous symptoms and extension of the tumor is discussed. with the literatures.

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Forty case which complained no sense of smell subjectively and did not respond to diluted solution of smell substance were studied. Venous olfactory test, X-ray with contrast medium (40% Molijodol) in either side of the olfactory clefts, and general observation were made.
Anosmia was divided into 3 types;
(A) morphorgenic, (B) neurogenic and (C) combined type.
The results obtained were as follows;
Group (A) was positive for venous olfoctory test. In 75%, molijodol was shown poorly on X-ray both olfactory clefts were obstructed due to severe swelling of inferior turbinates. The course was relatively short and intermittent.
Group (B) was negative for venous olfactory test. Molijodol was shown well and olfactory clefts were open. Middle turbinates were slightly swollen and the course of the disease was indefinite and continuous.
Group (C) was negative for venous olfactory test. Molijodol was shown poorly. In 70% of the cases, complete obstruction of both olfactory clefts was present due to severe swelling of middle turbinates and moderate atrophy of inferior turbinates was also seen. The course was relatively long and mainly continuous.
The order of diognostic tests for anosmia in clinical practice was discussed. It was tated that diagnosis of hyposmia can be performed in the same method and manner as for anosmia.

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A case of the Lermoyez's syndrome was reported. A 33 years old of man complained of the attack of vertigo, tinnitus, and deafness occuring at the rate of about once a month. Obviously these three symptoms were the syndrome of the Meniere's disease, but in this patient the order of the appearance of these symptoms was very characteristic, coinciding with the Williams's expression about the Lermoyez's syndrome: "increasing illuness, progressive deafness, then sudden vertigo and good hearing".
According to the observations and considerations about this case, the following conclusions were obtained. Previously, as the Lermoyez's syndrome the following characteristics has been recognized, that is, (1) in the pause between attacks the hearing of the patient remains approximate normal, and (2) in the course of attack, the apperence of three cardinal symptoms is in the inverted order of that of the Meniere's disease. Now the author add the one remark, namely, the patient's depressed hearing abruptly returns to the normal level instantly at the biginning of the vertigo.

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